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structural and functional properties of a single domain hemoglobin from the food-borne pathogen campylobactor jejuni
three-dimensional localization of serine 2808, a phosphorylation site in cardiac ryanodine receptor
jnk3 signaling pathway activates ceramide synthase leading to mitochondrial dysfunction
characterization and structure of a zn2+ and [2fe-2s]-containing copper chaperone from archaeoglobus fulgidus
phosphorylation of timap by glycogen synthase kinase-3 activates its associated protein phosphatase 1
induction of apoptosis is driven by nuclear retention of protein kinase c
promotion of cancer cell migration
a conserved mechanism for steroid receptor translocation to the plasma membrane
chaperone functions of the e3 ubiquitin ligase chip
enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products
glyceraldehyde-3-phosphate dehydrogenase enhances transcriptional activity of androgen receptor in prostate cancer cells
the human mucin muc4 is transcriptionally regulated by caudal-related homeobox, hepatocyte nuclear factors, forkhead box a, and gata endodermal transcription factor..
conformational changes that effect oligomerization and initiate pore formation are triggered throughout perfringolysin o upon binding to cholesterol
phenotypic and structural analyses of hepatitis c virus ns3 protease arg155 variants
elevated zeaxanthin bound to oligomeric lhcii enhances the resistance of arabidopsis to photooxidative stress by a lipid-protective, antioxidant mechanism
nucleotide excision repair eliminates unique dna-protein cross-links from mammalian cells
trpv6 is a ca2+ entry channel essential for ca2+-induced differentiation of human keratinocytes
the early growth response factor-1 is involved in stem cell factor (scf)-induced interleukin 13 production by mast cells, but is dispensable for scf-dependent mast ..
an integrin-tetraspanin interaction required for cellular innate immune responses of an insect, manduca sexta
translational repression of mcl-1 couples stress-induced eif2 phosphorylation to mitochondrial apoptosis initiation
a conserved cysteine is essential for pex4p-dependent ubiquitination of the peroxisomal import receptor pex5p
biochemical characterization of the atpase and helicase activity of uap56, an essential pre-mrna splicing and mrna export factor
differential regulation of atp binding cassette protein a1 expression and apoa-i lipidation by niemann-pick type c1 in murine hepatocytes and macrophages
insulin-like growth factor type-i receptor internalization and recycling mediate the sustained phosphorylation of akt
phosphorylation of stard10 on serine 284 by casein kinase ii modulates its lipid transfer activity
regulation of ergic-53 gene transcription in response to endoplasmic reticulum stress
phosphorylation of the -opioid receptor regulates its -arrestins selectivity and subsequent receptor internalization and adenylyl cyclase desensitization
loss of n-terminal charged residues of mouse cd3 chains generates isoforms modulating antigen t cell receptor-mediated signals and t cell receptor-cd3 interactions
pias3 interacts with atf1 and regulates the human ferritin h gene through an antioxidant-responsive element
characterizing early events associated with the activation of target genes by 1,25-dihydroxyvitamin d3 in mouse kidney and intestine in vivo
oleamide synthesizing activity from rat kidney
in vitro synthesis of oleoylglycine by cytochrome c points to a novel pathway for the production of lipid signaling molecules
identification of clec12b, an inhibitory receptor on myeloid cells
anti-a1–11 antibody binds to different -amyloid species, inhibits fibril formation, and disaggregates preformed fibrils but not the most toxic oligomers
atp-driven malk dimer closure and reopening and conformational changes of the “eaa“ motifs are crucial for function of the maltose atp-binding cassette transporte..
defects in the leptin axis reduce abundance of the abcg5-abcg8 sterol transporter in liver
n-terminal cleavage of gsk-3 by calpain
oxidative stress modulates complement factor h expression in retinal pigmented epithelial cells by acetylation of foxo3
structural basis for binding of plasmodium falciparum erythrocyte membrane protein 1 to chondroitin sulfate and placental tissue and the influence of protein polymo..
the size exclusion characteristics of type i collagen
hyperphagia-mediated obesity in transgenic mice misexpressing the rna-editing enzyme adar2
proteasome function is regulated by cyclic amp-dependent protein kinase through phosphorylation of rpt6
biogenesis of the essential tim9–tim10 chaperone complex of mitochondria
molecular and biochemical analysis of the plastidic adp-glucose transporter (zmbt1) from zea mays
the role of the poly(adp-ribose) polymerase tankyrase1 in telomere length control by the trf1 component of the shelterin complex
a kinase-anchoring protein 150 and calcineurin are involved in regulation of acid-sensing ion channels asic1a and asic2a
suppression of diacylglycerol acyltransferase-2 (dgat2), but not dgat1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance
species-specific differences in the intermediate states of human and syrian hamster prion protein detected by high pressure nmr spectroscopy
nmr shows hydrophobic interactions replace glycine packing in the triple helix at a natural break in the (gly-x-y)n repeat
rodent a modulates the solubility and distribution of amyloid deposits in transgenic mice
tlr-4 and sustained calcium agonists synergistically produce eicosanoids independent of protein synthesis in raw264.7 cells
interferon regulatory factor 3 is regulated by a dual phosphorylation-dependent switch
differentially spliced isoforms of fat1 are asymmetrically distributed within migrating cells
mechanistic studies of mdm2-mediated ubiquitination in p53 regulation
nucleotide-dependent allostery within the abc transporter atp-binding cassette
constitutive phosphorylation mutation in fas-associated death domain (fadd) results in early cell cycle defects
spatially segregated snare protein interactions in living fungal cells
allosteric activation of human glucokinase by free polyubiquitin chains and its ubiquitin-dependent cotranslational proteasomal degradation
liver-specific knockdown of jnk1 up-regulates proliferator-activated receptor coactivator 1 and increases plasma triglyceride despite reduced glucose and insulin le..
extracellular phosphorylation of collagen xvii by ecto-casein kinase 2 inhibits ectodomain shedding
receptor occupancy and channel-opening kinetics
a conserved physical and functional interaction between the cell cycle checkpoint clamp loader and dna ligase i of eukaryotes
nfbd1/mdc1 associates with p53 and regulates its function at the crossroad between cell survival and death in response to dna damage
mitochondrial fission and fusion mediators, hfis1 and opa1, modulate cellular senescence
a functional role for p38 mapk in modulating mitotic transit in the absence of stress
akt1 signaling regulates integrin activation, matrix recognition, and fibronectin assembly
dna internalized via caveolae requires microtubule-dependent, rab7-independent transport to the late endocytic pathway for delivery to the nucleus
the mre11-rad50-nbs1 complex acts both upstream and downstream of ataxia telangiectasia mutated and rad3-related protein (atr) to regulate the s-phase checkpoint fo..
the putative moss 3‘-phosphoadenosine-5‘-phosphosulfate reductase is a novel form of adenosine-5‘-phosphosulfate reductase without an iron-sulfur cluster
atp-induced structural transitions in pan, the proteasome-regulatory atpase complex in archaea
hcn2 and hcn4 isoforms self-assemble and co-assemble with equal preference to form functional pacemaker channels
differentiation of human circulating fibrocytes as mediated by transforming growth factor- and peroxisome proliferator-activated receptor
receptor-mediated regulation of tomosyn-syntaxin 1a interactions in bovine adrenal chromaffin cells
the transition to an elongation complex by t7 rna polymerase is a multistep process
effects of the isoform-specific characteristics of atf6 and atf6 on endoplasmic reticulum stress response gene expression and cell viability
neural precursor cells are protected from apoptosis induced by trophic factor withdrawal or genotoxic stress by inhibitors of glycogen synthase kinase 3
two alternative conformations of s-adenosyl-l-homocysteine bound to escherichia coli dna adenine methyltransferase and the implication of conformational changes in ..
the soxyz complex carries sulfur cycle intermediates on a peptide swinging arm
werner helicase-interacting protein 1 binds polyubiquitin via its zinc finger domain
structure of the complex of the colicin e2 r-domain and its btub receptor
opioid receptor pharmacological chaperones act by binding and stabilizing newly synthesized receptors in the endoplasmic reticulum
the different intermolecular interactions of the soluble copper-binding domains of the menkes protein, atp7a
the localization and activity of sphingosine kinase 1 are coordinately regulated with actin cytoskeletal dynamics in macrophages
activation of inhibitors by sortase triggers irreversible modification of the active site
g12/13-mediated up-regulation of trpc6 negatively regulates endothelin-1-induced cardiac myofibroblast formation and collagen synthesis through nuclear factor of ac..
functional links between the fusion peptide-proximal polar segment and membrane-proximal region of human immunodeficiency virus gp41 in distinct phases of membrane ..
targeting and retention of type 1 ryanodine receptors to the endoplasmic reticulum
mechanical stretching stimulates smooth muscle cell growth, nuclear protein import, and nuclear pore expression through mitogen-activated protein kinase activation
alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor
plap-1/asporin, a novel negative regulator of periodontal ligament mineralization
rat liver peroxisomes after fibrate treatment
nitric oxide down-regulates caveolin-3 levels through the interaction with myogenin, its transcription factor
structurally unique yeast and mammalian serine-arginine protein kinases catalyze evolutionarily conserved phosphorylation reactions
transient kinetic studies support refinements to the chemical and kinetic mechanisms of aminolevulinate synthase
ube1l2, a novel e1 enzyme specific for ubiquitin
improved stability of the jun-fos activator protein-1 coiled coil motif
structural analysis of conserved oligomeric golgi complex subunit 2
activation of glycogen synthase kinase 3 promotes the intermolecular association of tau
a novel approach for enzyme replacement therapy
functional genomic analysis reveals cross-talk between peroxisome proliferator-activated receptor and calcium signaling in human colorectal cancer cells
crystallographic and spectroscopic studies of peroxide-derived myoglobin compound ii and occurrence of protonated feiv–o
trafficking of a secretory granule membrane protein is sensitive to copper
solution structure of yaeo, a rho-specific inhibitor of transcription termination
mitofusin-2 is a major determinant of oxidative stress-mediated heart muscle cell apoptosis
fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition
the existence of multiple conformers of interleukin-21 directs engineering of a superpotent analogue
effect of calcium on calmodulin bound to the iq motifs of myosin v
regulation of pten activity by its carboxyl-terminal autoinhibitory domain
role of the guanine nucleotide exchange factor ost in negative regulation of receptor endocytosis by the small gtpase rac1
regulation of hyperoxia-induced nadph oxidase activation in human lung endothelial cells by the actin cytoskeleton and cortactin
functional implication of nucleolin in the mouse first molar development
functional promiscuity correlates with conformational heterogeneity in a-class glutathione s-transferases
a novel extrapallial fluid protein controls the morphology of nacre lamellae in the pearl oyster, pinctada fucata
interaction of integrin-linked kinase with the kidney chloride/bicarbonate exchanger, kae1
crystal structure of the n-terminal nc4 domain of collagen ix, a zinc binding member of the laminin-neurexin-sex hormone binding globulin (lns) domain family
crystal structure of human estrogen-related receptor in complex with a synthetic inverse agonist reveals its novel molecular mechanism
genetic evidence for a protective role for heat shock factor 1 and heat shock protein 70 against colitis
suppression of tubulin polymerization by the lkb1-microtubule-associated protein/microtubule affinity-regulating kinase signaling
structural basis of sterol binding by npc2, a lysosomal protein deficient in niemann-pick type c2 disease
co-chaperone fkbp38 promotes herg trafficking
paratope and epitope mapping of the antithrombotic antibody 6b4 in complex with platelet glycoprotein ib
rac1 signaling stimulates n-cadherin expression, mesenchymal condensation, and chondrogenesis
identification of peripherin as a akt substrate in neurons
regulation of c-src activity in glutamate-induced neurodegeneration
structural insights into catalysis and inhibition of o-acetylserine sulfhydrylase from mycobacterium tuberculosis
stabilization of hyperdynamic microtubules is neuroprotective in amyotrophic lateral sclerosis
structural and functional basis for (s)-allantoin formation in the ureide pathway
structural and functional characterization of a secreted hookworm macrophage migration inhibitory factor (mif) that interacts with the human mif receptor cd74
interdomain interaction in the fimh adhesin of escherichia coli regulates the affinity to mannose
vimentin is the specific target in skin glycation
p-rex1 links mammalian target of rapamycin signaling to rac activation and cell migration
differential association of hemoglobin with proinflammatory high density lipoproteins in atherogenic/hyperlipidemic mice
a novel form of 6-phosphofructokinase
high circulating leptin receptors with normal leptin sensitivity in liver-specific insulin receptor knock-out (lirko) mice
the effects of mtor-akt interactions on anti-apoptotic signaling in vascular endothelial cells
the carboxyl-terminal extension of yeast trna m5c methyltransferase enhances the catalytic efficiency of the amino-terminal domain
suppression of trpc3 leads to disappearance of store-operated channels and formation of a new type of store-independent channels in a431 cells
-secretase substrate concentration modulates the a42/a40 ratio
novel phosphorylation sites in tau from alzheimer brain support a role for casein kinase 1 in disease pathogenesis
protein kinase c (pkc) and src control pkc activation loop phosphorylation in cardiomyocytes
repression by binding of h-ns within the transcription unit
compartment-specific phosphorylation of phosducin in rods underlies adaptation to various levels of illumination
the neutrophil-specific antigen cd177 is a counter-receptor for platelet endothelial cell adhesion molecule-1 (cd31)
cytosolic aspartate aminotransferase, a new partner in adipocyte glyceroneogenesis and an atypical target of thiazolidinedione
a udp-glucose:isoflavone 7-o-glucosyltransferase from the roots of soybean (glycine max) seedlings
spermidine/spermine-n1-acetyltransferase 2 is an essential component of the ubiquitin ligase complex that regulates hypoxia-inducible factor 1
regulation of the gene encoding gpr40, a fatty acid receptor expressed selectively in pancreatic cells
the selective rna-binding protein quaking i (qki) is necessary and sufficient for promoting oligodendroglia differentiation
regulation of root nitrate uptake at the nrt2.1 protein level in arabidopsis thaliana
rb loss promotes aberrant ploidy by deregulating levels and activity of dna replication factors
importance of leu99 in transmembrane segment m1 of the na+,k+-atpase in the binding and occlusion of k+
structural variation governs substrate specificity for organic anion transporter (oat) homologs
protein-tyrosine phosphatase 1b deficiency reduces insulin resistance and the diabetic phenotype in mice with polygenic insulin resistance
accelerating amyloid- fibrillization reduces oligomer levels and functional deficits in alzheimer disease mouse models
abca3 is critical for lamellar body biogenesis in vivo
different t cell receptor affinity thresholds and cd8 coreceptor dependence govern cytotoxic t lymphocyte activation and tetramer binding properties
mitofusin 2 protects cerebellar granule neurons against injury-induced cell death
post-translational regulation of human indoleamine 2,3-dioxygenase activity by nitric oxide
selenoprotein h is a redox-sensing high mobility group family dna-binding protein that up-regulates genes involved in glutathione synthesis and phase ii detoxificat..
new insights into the reductive half-reaction mechanism of aromatic amine dehydrogenase revealed by reaction with carbinolamine substrates
binding of netrin-4 to laminin short arms regulates basement membrane assembly
the calponin homology domain of vav1 associates with calmodulin and is prerequisite to t cell antigen receptor-induced calcium release in jurkat t lymphocytes
the outer mitochondrial membrane protein mitoneet contains a novel redox-active 2fe-2s cluster
mir-221 and mir-222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27kip1
myosin vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in rab11a-specific apical recycling endosomes in polarized human ai..
drosophila ctr1a functions as a copper transporter essential for development
asparaginyl hydroxylation of the notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor
knock down of -glutamylcysteine synthetase in rat causes acetaminophen-induced hepatotoxicity
synapsis of loxp sites by cre recombinase
immediate-early and delayed primary response genes are distinct in function and genomic architecture
a receptor-binding site as revealed by the crystal structure of cfae, the colonization factor antigen i fimbrial adhesin of enterotoxigenic escherichia coli
elucidation of substrate specificity in the cobalamin (vitamin b12) biosynthetic methyltransferases
locking the kink in the influenza hemagglutinin fusion domain structure
cysteine scanning mutagenesis and disulfide mapping studies of the tata component of the bacterial twin arginine translocase
n-terminal truncation of antiapoptotic mcl1, but not g2/m-induced phosphorylation, is associated with stabilization and abundant expression in tumor cells
angiopoietin-1 requires p190 rhogap to protect against vascular leakage in vivo
roles of alternative splicing in the functional properties of inner ear-specific kcnq4 channels
the cb1 cannabinoid receptor mediates excitotoxicity-induced neural progenitor proliferation and neurogenesis
core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport
serum response factor contributes selectively to lymphocyte development
the cytosolic protein talin induces an intermediate affinity integrin l2
molecular architecture and divalent cation activation of tvok, a prokaryotic potassium channel
patch clamp and phenotypic analyses of a prokaryotic cyclic nucleotide-gated k+ channel using escherichia coli as a host
identification and characterization of vnx1p, a novel type of vacuolar monovalent cation/h+ antiporter of saccharomyces cerevisiae
missense mutations in apob within the 1 domain of human apob-100 result in impaired secretion of apob and apob-containing lipoproteins in familial hypobetalipoprote..
fibroblast growth factor 13 is essential for neural differentiation in xenopus early embryonic development
the human angiotensin ii type 1 receptor +1166 a/c polymorphism attenuates microrna-155 binding
concerted protonation of key histidines triggers membrane interaction of the diphtheria toxin t domain
dissection of a signaling pathway by which pathogen-associated molecular patterns recruit the jnk and p38 mapks and trigger cytokine release
kelch repeat protein interacts with the yeast g subunit gpa2p at a site that couples receptor binding to guanine nucleotide exchange
dual regulation of sirp phosphorylation by integrins and cd47
arabidopsis nip2;1, a major intrinsic protein transporter of lactic acid induced by anoxic stress
asymmetric and redox-specific binding of quinone and quinol at center n of the dimeric yeast cytochrome bc1 complex
glutamate-induced exocytosis of glutamate from astrocytes
the transcription factor runx3 represses the neurotrophin receptor trkb during lineage commitment of dorsal root ganglion neurons
identification of a serum component that regulates cyclooxygenase-2 gene expression in cooperation with 4-hydroxy-2-nonenal
detection of polyglutamine protein oligomers in cells by fluorescence correlation spectroscopy
neuropilin-1 binds to vegf121 and regulates endothelial cell migration and sprouting
distribution and structure-function relationship of myosin heavy chain isoforms in the adult mouse heart
hop/necc1, a novel regulator of mouse trophoblast differentiation
trb2, a mouse tribbles ortholog, suppresses adipocyte differentiation by inhibiting akt and c/ebp
soluble cd23 monomers inhibit and oligomers stimulate ige synthesis in human b cells
shuttling of g protein subunits between the plasma membrane and intracellular membranes
a family of g protein subunits translocate reversibly from the plasma membrane to endomembranes on receptor activation
acute lung injury edema fluid decreases net fluid transport across human alveolar epithelial type ii cells
glucocorticoids induce osteocyte apoptosis by blocking focal adhesion kinase-mediated survival
p62/sqstm1 binds directly to atg8/lc3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
mechanism of cell death caused by complex i defects in a rat dopaminergic cell line
-aminobutyric acid type b receptors are constitutively internalized via the clathrin-dependent pathway and targeted to lysosomes for degradation
potential new antibiotic sites in the ribosome revealed by deleterious mutations in rna of the large ribosomal subunit
the cyclin-dependent kinase inhibitors p15ink4b and p21cip1 are critical regulators of fibrillar collagen-induced tumor cell cycle arrest
cd98hc (slc3a2) interaction with the integrin subunit cytoplasmic domain mediates adhesive signaling
inhibition of mammalian target of rapamycin signaling by 2-(morpholin-1-yl)pyrimido[2,1-]isoquinolin-4-one
prerequisites for terminal processing of thylakoidal tat substrates
nuclear protein tia-1 regulates col2a1 alternative splicing and interacts with precursor mrna and genomic dna
6-s-cysteinylation of bi-covalently attached fad in berberine bridge enzyme tunes the redox potential for optimal activity
heme induces neutrophil migration and reactive oxygen species generation through signaling pathways characteristic of chemotactic receptors
the heparin/heparan sulfate sequence that interacts with cyclophilin b contains a 3-o-sulfated n-unsubstituted glucosamine residue
catalase takes part in rat liver mitochondria oxidative stress defense
involvement of cystic fibrosis transmembrane conductance regulator in mouse sperm capacitation
4-methyl sterols regulate fission yeast srebp-scap under low oxygen and cell stress
ptpl1/fap-1 negatively regulates trip6 function in lysophosphatidic acid-induced cell migration
zinc irreversibly damages major enzymes of energy production and antioxidant defense prior to mitochondrial permeability transition
modulation of intracellular signaling pathways to induce apoptosis in prostate cancer cells
g12 stimulates apoptosis in epithelial cells through jnk1-mediated bcl-2 degradation and up-regulation of ib
molecular cloning of a brain-specific, developmentally regulated neuregulin 1 (nrg1) isoform and identification of a functional promoter variant associated with sch..
a marriage of convenience: -subunits and voltage-dependent k+ channels
structural basis for the function of dcn-1 in protein neddylation
physical interaction between aldolase and vacuolar h+-atpase is essential for the assembly and activity of the proton pump
insensitivity to a42-lowering nonsteroidal anti-inflammatory drugs and -secretase inhibitors is common among aggressive presenilin-1 mutations
pras40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex
computer modeling of mitochondrial tricarboxylic acid cycle, oxidative phosphorylation, metabolite transport, and electrophysiology
glucose-induced cytosolic ph changes in -cells and insulin secretion are not causally related
voltage-independent sodium-binding events reported by the 4b-4c loop in the human glutamate transporter excitatory amino acid transporter 3
loss of huntingtin function complemented by small molecules acting as repressor element 1/neuron restrictive silencer element silencer modulators
female gender-specific inhibition of kcnq1 channels and chloride secretion by 17-estradiol in rat distal colonic crypts
elevation of cellular nad levels by nicotinic acid and involvement of nicotinic acid phosphoribosyltransferase in human cells
the birt-hogg-dube and tuberous sclerosis complex homologs have opposing roles in amino acid homeostasis in schizosaccharomyces pombe
interaction of cartilage oligomeric matrix protein/thrombospondin 5 with aggrecan
ceramide is a potent activator of plasma membrane ca2+-atpase from kidney proximal tubule cells with protein kinase a as an intermediate
activation of bile acid biosynthesis by the p38 mitogen-activated protein kinase (mapk)
variety of nucleotide sugar transporters with respect to the interaction with nucleoside mono- and diphosphates
protein phosphatase 2a and separase form a complex regulated by separase autocleavage
sirna screening of the kinome identifies ulk1 as a multidomain modulator of autophagy
anaerobic acclimation in chlamydomonas reinhardtii
the length dependence of the polyq-mediated protein aggregation
identification of a specific exosite on activated protein c for interaction with protease-activated receptor 1
a novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblast mechanotransduction
constitutively active parathyroid hormone receptor signaling in cells in osteoblastic lineage suppresses mechanical unloading-induced bone resorption
synapse specificity of calcium release probed by chemical two-photon uncaging of inositol 1,4,5-trisphosphate
intrinsic differences in the response of the human lutropin receptor versus the human follitropin receptor to activating mutations
multiple pocket recognition of snap25 by botulinum neurotoxin serotype e
heteromeric assembly of acid-sensitive ion channel and epithelial sodium channel subunits
dynamics of arrestin-rhodopsin interactions
the atpase activity of the dna transporter trwb is modulated by protein trwa
protective role of mitochondrial unsaturated lipids on the preservation of the apoptotic ability of cytochrome c exposed to singlet oxygen
novel plant-specific cyclin-dependent kinase inhibitors induced by biotic and abiotic stresses
expression and subcellular localization of a novel nuclear acetylcholinesterase protein
prr5, a novel component of mtor complex 2, regulates platelet-derived growth factor receptor expression and signaling
leaky scanning and scanning-independent ribosome migration on the tricistronic s1 mrna of avian reovirus
auto-catalytic cleavage of clostridium difficile toxins a and b depends on cysteine protease activity
cloning and characterization of the rat lysyl oxidase gene promoter
talin 1 and paxillin facilitate distinct steps in rapid vla-4-mediated adhesion strengthening to vascular cell adhesion molecule 1
lateral diffusion of the gabab receptor is regulated by the gabab2 c terminus
biliprotein chromophore attachment
proteolysis at arg740 facilitates subsequent bond cleavages during thrombin-catalyzed activation of factor viii
mosquito heparan sulfate and its potential role in malaria infection and transmission
direct and indirect interactions of the cytoplasmic region of cd244 (2b4) in mice and humans with fyn kinase
feedback inhibition of pantothenate kinase regulates pantothenol uptake by the malaria parasite
ultrasound induces hypoxia-inducible factor-1 activation and inducible nitric-oxide synthase expression through the integrin/integrin-linked kinase/akt/mammalian ta..
tissue factor coagulant function is enhanced by protein-disulfide isomerase independent of oxidoreductase activity
r3(b23–27)r/i5 chimeric peptide, a selective antagonist for gpcr135 and gpcr142 over relaxin receptor lgr
x-ray structural analysis of plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacy
role of mapk phosphatase-1 in the induction of monocyte chemoattractant protein-1 during the course of adipocyte hypertrophy
structure of substrate-free human insulin-degrading enzyme (ide) and biophysical analysis of atp-induced conformational switch of ide
discovery and characterization of a second mammalian thiol dioxygenase, cysteamine dioxygenase
the importance of n-terminal polycysteine and polybasic sequences for g14 and g16 palmitoylation, plasma membrane localization, and signaling function
domain organization and movements in heavy metal ion pumps
three surface subdomains form the vestibule of the na+/glucose cotransporter sglt1
interactions of the vitamin d receptor with the corepressor hairless
influence of the protein environment on the redox potentials of flavodoxins from clostridium beijerinckii
eif4g, eifiso4g, and eif4b bind the poly(a)-binding protein through overlapping sites within the rna recognition motif domains
reconstitution and characterization of a nicotinic acid adenine dinucleotide phosphate (naadp)-sensitive ca2+ release channel from liver lysosomes of rats
isolation and characterization of a dominant negative mutant of bacillus subtilis gtp-binding protein, ylqf, essential for biogenesis and maintenance of the 50 s ri..
group via phospholipase a2 (ipla2) participates in angiotensin ii-induced transcriptional up-regulation of regulator of g-protein signaling-2 in vascular smooth mus..
amino acid residues in transmembrane segment ix of the na+/i– symporter play a role in its na+ dependence and are critical for transport activity
n-methyl-d-aspartate (nmda) receptor subunit nr1 forms the substrate for oligomeric assembly of the nmda receptor
activation-induced cytidine deaminase-mediated sequence diversification is transiently targeted to newly integrated dna substrates
constitutive activation of tak1 by htlv-1 tax-dependent overexpression of tab2 induces activation of jnk-atf2 but not ikk-nf-b
ccr2 chemokines bind selectively to acetylated heparan sulfate octasaccharides
hydrogen bonds between nitrogen donors and the semiquinone in the qi-site of the bc1 complex
glial cell line-derived neurotrophic factor regulation of genes essential for self-renewal of mouse spermatogonial stem cells is dependent on src family kinase sign..
relationships between transforming growth factor-1, myostatin, and decorin
binding of adam28 to p-selectin glycoprotein ligand-1 enhances p-selectin-mediated leukocyte adhesion to endothelial cells
endogenous erythropoietin signaling is required for normal neural progenitor cell proliferation
global structure changes associated with ca2+ activation of full-length human plasma gelsolin
the tandem -zipper model defines high affinity fibronectin-binding repeats within staphylococcus aureus fnbpa
replisome fate upon encountering a leading strand block and clearance from dna by recombination proteins
investigation of early tailoring reactions in the oxytetracycline biosynthetic pathway
partial agonism and antagonism of the ionotropic glutamate receptor iglur
structural and membrane binding analysis of the phox homology domain of bem1p
transcriptional repression by the t-box proteins tbx18 and tbx15 depends on groucho corepressors
h-ras does not need cop i- or cop ii-dependent vesicular transport to reach the plasma membrane
protein-bound 4-hydroxy-2-nonenal
exosomes released from infected macrophages contain mycobacterium avium glycopeptidolipids and are proinflammatory
haploinsufficient prostate tumor suppression by nkx3.
modulation of androgen receptor activation function 2 by testosterone and dihydrotestosterone
molecular determinants of mg2+ and ca2+ permeability and ph sensitivity in trpm6 and trpm7
transducing agonist binding to channel gating involves different interactions in 5-ht3 and gabac receptors
conserved residue lys574 in the cavity of hiv-1 gp41 coiled-coil domain is critical for six-helix bundle stability and virus entry
the plasma membrane ca2+ pump isoform 4a differs from isoform 4b in the mechanism of calmodulin binding and activation kinetics
disruption of the insulin-like growth factor type 1 receptor in osteoblasts enhances insulin signaling and action
essential, completely conserved glycine residue in the domain iii s2–s3 linker of voltage-gated calcium channel 1 subunits in yeast and mammals
multiple and additive functions of aldh3a1 and aldh1a
critical role for the second extracellular loop in the binding of both orthosteric and allosteric g protein-coupled receptor ligands
involvement of hyaluronan in regulation of fibroblast phenotype
site-directed mutagenesis in the b-neuropilin-2 domain selectively enhances its affinity to vegf165, but not to semaphorin 3f
a novel role of brg1 in the regulation of srf/mrtfa-dependent smooth muscle-specific gene expression
intramolecular control of protein stability, subnuclear compartmentalization, and coactivator function of peroxisome proliferator-activated receptor coactivator 1
asymmetric binding of stigmatellin to the dimeric paracoccus denitrificans bc1 complex
characterization of the properties and trafficking of an anchorless form of the prion protein
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