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clathrin-mediated endocytosis and lysosomal cleavage of hepatitis b virus capsid-like core particles
structural basis of reduction-dependent activation of human cystatin f
mutagenesis and molecular modeling reveal the importance of the 5-ht3 receptor f-loop
regulation of nr1/nr2c n-methyl-d-aspartate (nmda) receptors by phosphorylation
regulation of cell adhesion by protein-tyrosine phosphatases
functional analysis of recombinant mutants of maxadilan with a pac1 receptor-expressing melanophore cell line
identification of far upstream element-binding protein-1 as an authentic parkin substrate
a random-sequential mechanism for nitrite binding and active site reduction in copper-containing nitrite reductase
functional implication of neuronal calcium sensor-1 and phosphoinositol 4-kinase- interaction in regulated exocytosis of pc12 cells
characterization of native retinal fluorophores involved in biosynthesis of a2e and lipofuscin-associated retinopathies
novel mutants of the human 1-adrenergic receptor reveal amino acids relevant for receptor activation
the swi2/snf2 bromodomain is required for the displacement of saga and the octamer transfer of saga-acetylated nucleosomes
complete structures of bordetella bronchiseptica and bordetella parapertussis lipopolysaccharides
metastatic potential of mouse lewis lung cancer cells is regulated via ganglioside gm1 by modulating the matrix metalloprotease-9 localization in lipid rafts
active and passive mechanisms drive secretory granule biogenesis during differentiation of the intestinal parasite giardia lamblia
local unfolding in a destabilized, pathogenic variant of superoxide dismutase 1 observed with h/d exchange and mass spectrometry
activated jak2 with the v617f point mutation promotes g1/s phase transition
evolutionarily conserved allosteric network in the cys loop family of ligand-gated ion channels revealed by statistical covariance analyses
crystal structure of the herpes simplex virus 1 dna polymerase
regulation of bruton tyrosine kinase by the peptidylprolyl isomerase pin1
the carboxyl-terminal nucleoplasmic region of man1 exhibits a dna binding winged helix domain
structural, biochemical, and dynamic characterizations of the hrpb8 subunit of human rna polymerases
the multi-kh domain protein of saccharomyces cerevisiae scp160p contributes to the regulation of telomeric silencing
the phosphotyrosine peptide binding specificity of nck1 and nck2 src homology 2 domains
the estrogen-responsive b box protein is a novel regulator of the retinoid signal
identification and characterization of versican/pg-m aggregates in cartilage
role of nf-b in regulation of pxr-mediated gene expression
cholesterol accumulation sequesters rab9 and disrupts late endosome function in npc1-deficient cells
genetic requirements for growth of escherichia coli k12 on methyl--d-glucopyranoside and the five -d-glucosyl-d-fructose isomers of sucrose
identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity
molecular analysis of ulilysin, the structural prototype of a new family of metzincin metalloproteases
amino acid starvation induces the snat2 neutral amino acid transporter by a mechanism that involves eukaryotic initiation factor 2 phosphorylation and cap-independe..
neprilysin-sensitive synapse-associated amyloid- peptide oligomers impair neuronal plasticity and cognitive function
hyaluronan oligosaccharides induce matrix metalloproteinase 13 via transcriptional activation of nfb and p38 map kinase in articular chondrocytes
vascular endothelial growth factor-d activates vegfr-3 expressed in osteoblasts inducing their differentiation
dissecting the biological functions of drosophila histone deacetylases by rna interference and transcriptional profiling
lys-d48 is required for charge stabilization, rapid flavin reduction, and internal electron transfer in the catalytic cycle of dihydroorotate dehydrogenase b of lac..
oep37 is a new member of the chloroplast outer membrane ion channels
protective effects of catalase overexpression on uvb-induced apoptosis in normal human keratinocytes
contributions of phenylalanine 335 to ligand recognition by human surfactant protein d
nrf2 negatively regulates osteoblast differentiation via interfering with runx2-dependent transcriptional activation
structure of rhlg, an essential -ketoacyl reductase in the rhamnolipid biosynthetic pathway of pseudomonas aeruginosa
aspartyl-trna synthetase is the target of peptide nucleotide antibiotic microcin c
identification of a co-repressor that inhibits the transcriptional and growth-arrest activities of ccaat/enhancer-binding protein
kappa opioid receptor activation of p38 mapk is grk3- and arrestin-dependent in neurons and astrocytes
inhibition of the mitotic kinesin eg5 up-regulates hsp70 through the phosphatidylinositol 3-kinase/akt pathway in multiple myeloma cells
apoptosis induction by activator protein 2 involves transcriptional repression of bcl-2
pseudomonas aeruginosa porin oprf exists in two different conformations
pseudomonas aeruginosa porin oprf
intracellular actions of group iia secreted phospholipase a2 and group iva cytosolic phospholipase a2 contribute to arachidonic acid release and prostaglandin produ..
new insights into bs69 functions
one single in-frame aug codon is responsible for a diversity of subcellular localizations of glutaredoxin 2 in saccharomyces cerevisiae
evidence against functionally significant aquaporin expression in mitochondria
modulation of kv3.1b potassium channel phosphorylation in auditory neurons by conventional and novel protein kinase c isozymes
arginine-vasopressin activates the jak-stat pathway in vascular smooth muscle cells
orphan nuclear receptor nur77 induces zinc finger protein giot-1 gene expression, and giot-1 acts as a novel corepressor of orphan nuclear receptor sf-1 via recruit..
highly selective hydrolysis of fatty acyl-coas by calcium-independent phospholipase a
mitochondrial localization and putative signaling function of sucrose synthase in maize
stat3 as a downstream mediator of trk signaling and functions
the nuclear localization of erk2 occurs by mechanisms both independent of and dependent on energy
identification of a novel arabinofuranosyltransferase (afta) involved in cell wall arabinan biosynthesis in mycobacterium tuberculosis
arabidopsis thaliana vtc4 encodes l-galactose-1-p phosphatase, a plant ascorbic acid biosynthetic enzyme
differential sorting of the vesicular glutamate transporter 1 into a defined vesicular pool is regulated by light signaling involving the clock gene period2
the mure synthetase from thermotoga maritima is endowed with an unusual d-lysine adding activity
heme oxygenase-1 enhances renal mitochondrial transport carriers and cytochrome c oxidase activity in experimental diabetes
receptor specificity of the fibroblast growth factor family
rhodobacter capsulatus xdhc is involved in molybdenum cofactor binding and insertion into xanthine dehydrogenase
seca supports a constant rate of preprotein translocation
identification of the mll2 complex as a coactivator for estrogen receptor
binding of a single rb+ increases na+/k+-atpase, activating dephosphorylation without stoichiometric occlusion
the substrate radical of escherichia coli oxygen-independent coproporphyrinogen iii oxidase hemn
a high mobility group protein binds to long cag repeat tracts and establishes their chromatin organization in saccharomyces cerevisiae
the fatc domains of pikk proteins are functionally equivalent and participate in the tip60-dependent activation of dna-pkcs and atm
phospholipase d1 regulates cell migration in a lipase activity-independent manner
composition of perineuronal net extracellular matrix in rat brain
characterization of a novel protein kinase d
conserved domains subserve novel mechanisms and functions in dkf-1, a caenorhabditis elegans protein kinase d
adamts1 interacts with, cleaves, and modifies the extracellular location of the matrix inhibitor tissue factor pathway inhibitor-2
energetics of interaction between the g-protein chaperone, meab, and b12-dependent methylmalonyl-coa mutase
na+/h+ exchanger nhe3 activity and trafficking are lipid raft-dependent
the glucocorticoid receptor represses cyclin d1 by targeting the tcf--catenin complex
structural role for tyr-104 in escherichia coli isopentenyl-diphosphate isomerase
functional repression of camp response element in 6-hydroxydopamine-treated neuronal cells
caspase-2 triggers bax-bak-dependent and -independent cell death in colon cancer cells treated with resveratrol
a g316a mutation of manganese lipoxygenase augments hydroperoxide isomerase activity
the stimulus-induced tyrosine phosphorylation of munc18c facilitates vesicle exocytosis
the constitutive expression of anticoagulant protein s is regulated through multiple binding sites for sp1 and sp3 transcription factors in the protein s gene promo..
differential regulation of the human tyrosine hydroxylase isoforms via hierarchical phosphorylation
mitogenic responses of vascular smooth muscle cells to lipid peroxidation-derived aldehyde 4-hydroxy-trans-2-nonenal (hne)
role of glutaredoxin-3 and glutaredoxin-4 in the iron regulation of the aft1 transcriptional activator in saccharomyces cerevisiae
zinc transport complexes contribute to the homeostatic maintenance of secretory pathway function in vertebrate cells
adenomatous polyposis coli (apc) differentially regulates -catenin phosphorylation and ubiquitination in colon cancer cells
urokinase signaling through its receptor protects against anoikis by increasing bcl-xl expression levels
identification and characterization of a new class of bilin lyase
identification of proteins cleaved downstream of caspase activation in monocytes undergoing macrophage differentiation
constitutive receptor-independent low density lipoprotein uptake and cholesterol accumulation by macrophages differentiated from human monocytes with macrophage-col..
evidence that dna (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus
probes of the catalytic site of cysteine dioxygenase
distinct subcellular localization for constitutive and agonist-modulated palmitoylation of the human opioid receptor
functional interactions of phospholemman (plm) (fxyd1) with na+,k+-atpase
adamts-12 associates with and degrades cartilage oligomeric matrix protein
rankl stimulates inducible nitric-oxide synthase expression and nitric oxide production in developing osteoclasts
hyaluronan synthesis induces microvillus-like cell surface protrusions
structure of severe acute respiratory syndrome coronavirus receptor-binding domain complexed with neutralizing antibody
perilipin promotes hormone-sensitive lipase-mediated adipocyte lipolysis via phosphorylation-dependent and -independent mechanisms
phosphatidylinositol phosphates as co-activators of ca2+ binding to c2 domains of synaptotagmin 1
evidence that fibulin family members contribute to the steroid-dependent extravascular sequestration of sex hormone-binding globulin
phospholipase d couples survival and migration signals in stress response of human cancer cells
characterization of a family of nucleolar sumo-specific proteases with preference for sumo-2 or sumo-3
generation of a stable activated thrombin activable fibrinolysis inhibitor variant
specific regulation of irs-2 expression by glucose in rat primary pancreatic islet -cells
cystatin m/e is a high affinity inhibitor of cathepsin v and cathepsin l by a reactive site that is distinct from the legumain-binding site
solution structure of human peptidyl prolyl isomerase-like protein 1 and insights into its interaction with skip
interaction between rax and pkr modulates the effect of ethanol on protein synthesis and survival of neurons
expression and characterization of full-length human huntingtin, an elongated heat repeat protein
loss of a primordial identity element for a mammalian mitochondrial aminoacylation system
smpb triggers gtp hydrolysis of elongation factor tu on ribosomes by compensating for the lack of codon-anticodon interaction during trans-translation initiation
atp binding to a unique site in the type-1 s2- inositol 1,4,5-trisphosphate receptor defines susceptibility to phosphorylation by protein kinase a
two-photon imaging of glutathione levels in intact brain indicates enhanced redox buffering in developing neurons and cells at the cerebrospinal fluid and blood-bra..
neuroprotection of tat-glur6-9c against neuronal death induced by kainate in rat hippocampus via nuclear and non-nuclear pathways
dna and rna as new binding targets of green tea catechins
jab1 induces the cytoplasmic localization and degradation of p53 in coordination with hdm2
repletion of atypical protein kinase c following rna interference-mediated depletion restores insulin-stimulated glucose transport
hepatitis b virus capsid-like particles can display the complete, dimeric outer surface protein c and stimulate production of protective antibody responses against ..
nuclear ataxia-telangiectasia mutated (atm) mediates the cellular response to dna double strand breaks in human neuron-like cells
autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine to lysophosphatidic acid
a new motif necessary and sufficient for stable localization of the 2 glutamate receptors at postsynaptic spines
a novel, topologically constrained dna molecule containing a double holliday junction
lysosomal localization of trpml3 depends on trpml2 and the mucolipidosis-associated protein trpml1
mechanism of proliferating cell nuclear antigen clamp opening by replication factor c
inhibiting bacterial fatty acid synthesis
biogenesis of functional antigenic peptide transporter tap requires assembly of pre-existing tap1 with newly synthesized tap2
gadd45a and gadd45b protect hematopoietic cells from uv-induced apoptosis via distinct signaling pathways, including p38 activation and jnk inhibition
s-trityl-l-cysteine is a reversible, tight binding inhibitor of the human kinesin eg5 that specifically blocks mitotic progression
the monomer/dimer transition of enzyme i of the escherichia coli phosphotransferase system
properties of the c-terminal domain of enzyme i of the escherichia coli phosphotransferase system
additional sex comb-like 1 (asxl1), in cooperation with src-1, acts as a ligand-dependent coactivator for retinoic acid receptor
dimeric dnm1-g385d interacts with mdv1 on mitochondria and can be stimulated to assemble into fission complexes containing mdv1 and fis1
reversible membrane interaction of bad requires two c-terminal lipid binding domains in conjunction with 14-3-3 protein binding
metal ion site engineering indicates a global toggle switch model for seven-transmembrane receptor activation
ca2+-dependent control of the permeability properties of the mitochondrial outer membrane and voltage-dependent anion-selective channel (vdac)
cyanidin-3-glucoside, a natural product derived from blackberry, exhibits chemopreventive and chemotherapeutic activity
selective inhibition of endoplasmic reticulum-associated degradation rescues f508-cystic fibrosis transmembrane regulator and suppresses interleukin-8 levels
the role of calmodulin recruitment in ca2+ stimulation of adenylyl cyclase type 8
roles of the active site water, histidine 303, and phenylalanine 396 in the catalytic mechanism of the elongation condensing enzyme of streptococcus pneumoniae
crystal structure of the human foxk1a-dna complex and its implications on the diverse binding specificity of winged helix/forkhead proteins
activity-based protein profiling implicates urokinase activation as a key step in human fibrosarcoma intravasation
a conformational switch in vinculin drives formation and dynamics of a talin-vinculin complex at focal adhesions
ubiquitous calpains promote caspase-12 and jnk activation during endoplasmic reticulum stress-induced apoptosis
puma dissociates bax and bcl-xl to induce apoptosis in colon cancer cells
transformation by the rho-specific guanine nucleotide exchange factor dbs requires rock i-mediated phosphorylation of myosin light chain
differential binding of erythroid krupple-like factor to embryonic/fetal globin gene promoters during development
nitric oxide signaling via nuclearized endothelial nitric-oxide synthase modulates expression of the immediate early genes inos and mpges-1
regulation of albumin endocytosis by psd95/dlg/zo-1 (pdz) scaffolds
control of intrinsically disordered stathmin by multisite phosphorylation
a conditional mutant deficient in hypoxanthine-guanine phosphoribosyltransferase and xanthine phosphoribosyltransferase validates the purine salvage pathway of leis..
nf-y and ccaat/enhancer-binding protein synergistically activate the mouse amelogenin gene
the 19 s proteasomal subunit poh1 contributes to the regulation of c-jun ubiquitination, stability, and subcellular localization
identification of a ph sensor in the furin propeptide that regulates enzyme activation
specification of sumo1- and sumo2-interacting motifs
phosphatidylinositol 3-kinase signaling through protein kinase c induces nadph oxidase-mediated oxidant generation and nf-b activation in endothelial cells
plasma membrane domains specialized for clathrin-mediated endocytosis in primary cells
optineurin increases cell survival and translocates to the nucleus in a rab8-dependent manner upon an apoptotic stimulus
domain interactions within fzo1 oligomers are essential for mitochondrial fusion
the c5 domain of the collagen vi 3(vi) chain is critical for extracellular microfibril formation and is present in the extracellular matrix of cultured cells
identification of the expressed form of human cytosolic phospholipase a2 (cpla2)
contribution of amino acid side chains to sugar binding specificity in a galactokinase, gal1p, and a transcriptional inducer, gal3p
a dishevelled-1/smad1 interaction couples wnt and bone morphogenetic protein signaling pathways in uncommitted bone marrow stromal cells
alternative splicing controls neuronal expression of v-atpase subunit a1 and sorting to nerve terminals
focal adhesions in (myo)fibroblasts scaffold adenylyl cyclase with phosphorylated caveolin
histone h3 lysine 4 dimethylation signals the transcriptional competence of the adiponectin promoter in preadipocytes
a plant locus essential for phylloquinone (vitamin k1) biosynthesis originated from a fusion of four eubacterial genes
conformational features of a natural break in the type iv collagen gly-x-y repeat
conserved loop sequence of helix 69 in escherichia coli 23 s rrna is involved in a-site trna binding and translational fidelity
lim mineralization protein-1 potentiates bone morphogenetic protein responsiveness via a novel interaction with smurf1 resulting in decreased ubiquitination of smads
heat shock protein 25 or inducible heat shock protein 70 activates heat shock factor
a truncated p2x7 receptor variant (p2x7-j) endogenously expressed in cervical cancer cells antagonizes the full-length p2x7 receptor through hetero-oligomerization
the importance of the strictly conserved, c-terminal glycine residue in phosphoenolpyruvate carboxylase for overall catalysis
a serpin from the gut bacterium bifidobacterium longum inhibits eukaryotic elastase-like serine proteases
soluble adenylyl cyclase mediates nerve growth factor-induced activation of rap1
a zinc-binding region in vif binds cul5 and determines cullin selection
affinity-defining domains in the na-cl cotransporter
distinct properties of the five udp-d-glucose/udp-d-galactose 4-epimerase isoforms of arabidopsis thaliana
laminin 3 forms a complex with 3 and 3 chains that serves as the ligand for 61-integrin at the apical ectoplasmic specialization in adult rat testes
functional expression of thermo-transient receptor potential channels in dental primary afferent neurons
estrogen receptor mediates 17-ethynylestradiol causing hepatotoxicity
a second thylakoid membrane-localized alb3/oxai/yidc homologue is involved in proper chloroplast biogenesis in arabidopsis thaliana
a structure-based approach to retinoid x receptor- inhibition
the presenilin-2 loop peptide perturbs intracellular ca2+ homeostasis and accelerates apoptosis
catch bond-mediated adhesion without a shear threshold
sumoylation delimits klf8 transcriptional activity associated with the cell cycle regulation
sp1 is up-regulated in cellular and transgenic models of huntington disease, and its reduction is neuroprotective
ghrelin and the growth hormone secretagogue receptor constitute a novel autocrine pathway in astrocytoma motility
metalloprotease inhibitors gm6001 and tapi-0 inhibit the obligate intracellular human pathogen chlamydia trachomatis by targeting peptide deformylase of the bacterium
identification of the mitochondrial targeting signal of the human equilibrative nucleoside transporter 1 (hent1)
membrane accumulation of influenza a virus hemagglutinin triggers nuclear export of the viral genome via protein kinase c-mediated activation of erk signaling
erm/thyroid transcription factor 1 interactions modulate surfactant protein c transcription
heteromeric, but not homomeric, connexin channels are selectively permeable to inositol phosphates
subcellular localization and structural function of endogenous phosphorylated phosphatidylinositol 4-kinase (pi4k92)
a pool of extramitochondrial frataxin that promotes cell survival
up-regulation of the angiotensin ii type 1 receptor by the mas proto-oncogene is due to constitutive activation of gq/g11 by mas
differential metabolomics reveals ophthalmic acid as an oxidative stress biomarker indicating hepatic glutathione consumption
functional consequences of a mutation in an expressed human -cardiac actin at a site implicated in familial hypertrophic cardiomyopathy
the structure of g protein-coupled receptor kinase (grk)-6 defines a second lineage of grks
all but the shortest polymorphic forms of the viral receptor dc-signr assemble into stable homo- and heterotetramers
differential interactions between transforming growth factor-3/tr1, tab1, and cd2ap disrupt blood-testis barrier and sertoli-germ cell adhesion
hdm2 nuclear export, regulated by insulin-like growth factor-i/mapk/p90rsk signaling, mediates the transformation of human cells
erk8 down-regulates transactivation of the glucocorticoid receptor through hic-5
apobec3b and apobec3f inhibit l1 retrotransposition by a dna deamination-independent mechanism
a novel enzyme conferring streptothricin resistance alters the toxicity of streptothricin d from broad-spectrum to bacteria-specific
metabolism of myeloperoxidase-derived 2-chlorohexadecanal
the ubiquitin-like protein mnsf regulates erk-mapk cascade
transcriptional regulation of the xenopus laevis stromelysin-3 gene by thyroid hormone is mediated by a dna element in the first intron
characterization of the exchangeable protons in the immediate vicinity of the semiquinone radical at the qh site of the cytochrome bo3 from escherichia coli
the two-stage pathway of ataxin-3 fibrillogenesis involves a polyglutamine-independent step
o-glycosylation regulates autolysis of cellular membrane type-1 matrix metalloproteinase (mt1-mmp)
second messenger function of nicotinic acid adenine dinucleotide phosphate revealed by an improved enzymatic cycling assay
structural and functional characterization of an essential rtx subdomain of bordetella pertussis adenylate cyclase toxin
steroid and xenobiotic receptor sxr mediates vitamin k2-activated transcription of extracellular matrix-related genes and collagen accumulation in osteoblastic cells
physiological consequences of loss of allosteric activation of yeast nad+-specific isocitrate dehydrogenase
excess hdm2 impacts cell cycle and apoptosis and has a selective effect on p53-dependent transcription
regulation of cgmp-dependent protein kinase expression by rho and krüppel-like transcription factor-4
carboxyl terminus of plakophilin-1 recruits it to plasma membrane, whereas amino terminus recruits desmoplakin and promotes desmosome assembly
purification and initial biochemical characterization of atp:cob(i)alamin adenosyltransferase (eutt) enzyme of salmonella enterica
the two plasmodium falciparum nucleosome assembly proteins play distinct roles in histone transport and chromatin assembly
novel anti-inflammatory role for glycogen synthase kinase-3 in the inhibition of tumor necrosis factor-- and interleukin-1-induced inflammatory gene expression
heat shock induces apoptosis independently of any known initiator caspase-activating complex
redox balance mechanisms in schistosoma mansoni rely on peroxiredoxins and albumin and implicate peroxiredoxins as novel drug targets
identification of distinct inhibin and transforming growth factor -binding sites on betaglycan
plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses nf-b activation and nf-b-regulated gene products through modulation of p65 and ib kinase activation, le..
an asymmetric contribution to -aminobutyric type a receptor function of a conserved lysine within tm2-3 of 1, 2, and 2 subunits
kinetic mechanisms of the oxygenase from a two-component enzyme, p-hydroxyphenylacetate 3-hydroxylase from acinetobacter baumannii
adp-ribosyltransferase-specific modification of human neutrophil peptide-1
limited mutations in full-length tetrameric human 2-macroglobulin abrogate binding of platelet-derived growth factor-bb and transforming growth factor-1
an expanded ww domain recognition motif revealed by the interaction between smad7 and the e3 ubiquitin ligase smurf2
identification of snap-47, a novel qbc-snare with ubiquitous expression
the genetic stability of a conditional live hiv-1 variant can be improved by mutations in the tet-on regulatory system that restrain evolution
absence of dysferlin alters myogenin expression and delays human muscle differentiation “in vitro“
family 6 carbohydrate binding modules in -agarases display exquisite selectivity for the non-reducing termini of agarose chains
a common site of the fc receptor subunit interacts with the unrelated immunoreceptors fcri and fcri
transcription regulation of ompf and ompc by a single transcription factor, ompr
moz-tif2 alters cofactor recruitment and histone modification at the rar2 promoter
crystal structure of the severe acute respiratory syndrome (sars) coronavirus nucleocapsid protein dimerization domain reveals evolutionary linkage between corona- ..
membrane localization of adenomatous polyposis coli protein at cellular protrusions
activation of tyk2 and stat3 is required for the apoptotic actions of interferon- in primary pro-b cells
cyclin d1-cdk4 induce runx2 ubiquitination and degradation
nadp-dependent mannitol dehydrogenase, a major allergen of cladosporium herbarum
depletion of hsp90 induces multiple defects in b cell receptor signaling
nmr and alanine scan studies of glucose-dependent insulinotropic polypeptide in water
a protein in crude cytosol regulates glucose-6-phosphatase activity in crude microsomes to regulate group size in dictyostelium
identification of a ca2+-atpase in brown adipose tissue mitochondria
post-translational modifications of the four conserved lysine residues within the collagenous domain of adiponectin are required for the formation of its high molec..
complementation of saccharomyces cerevisiae coq7 mutants by mitochondrial targeting of the escherichia coli ubif polypeptide
identification of functionally relevant residues of the rat ileal apical sodium-dependent bile acid cotransporter
adam10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced -secretase cleavage of amyloid precursor protein
coordinate inhibition of cytokine-mediated induction of ferritin h, manganese superoxide dismutase, and interleukin-6 by the adenovirus e1a oncogene
opposing roles for erk1/2 in neuronal oxidative toxicity
c-jun n-terminal kinase-mediated stabilization of microsomal prostaglandin e2 synthase-1 mrna regulates delayed microsomal prostaglandin e2 synthase-1 expression an..
sp1 and sp3 mediate constitutive transcription of the human hyaluronan synthase 2 gene
translocator proteins in the two-partner secretion family have multiple domains
dot1a-af9 complex mediates histone h3 lys-79 hypermethylation and repression of enac in an aldosterone-sensitive manner
expression of a functional drosophila melanogaster cmp-sialic acid synthetase
vinblastine-induced apoptosis is mediated by discrete alterations in subcellular location, oligomeric structure, and activation status of specific bcl-2 family memb..
conserved receptor-binding domains of lake victoria marburgvirus and zaire ebolavirus bind a common receptor
identification of key functional domains in the c terminus of the k+-cl- cotransporters
myelin-associated glycoprotein inhibits microtubule assembly by a rho-kinase-dependent mechanism
differential recognition of citrate and a metal-citrate complex by the bacterial chemoreceptor tcp
phosphoinositide 3-kinase in nitric oxide synthesis in macrophage
structural basis of the sphingomyelin phosphodiesterase activity in neutral sphingomyelinase from bacillus cereus
nmr structure of the full-length linear dimer of stem-loop-1 rna in the hiv-1 dimer initiation site
opposing roles of zyxin/lpp acta repeats and the lim domain region in cell-cell adhesion
distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo
caat/enhancer-binding protein and camp-response element-binding protein mediate inducible expression of the nerve growth factor gene in the central nervous system
ubiquitous calpains promote both apoptosis and survival signals in response to different cell death stimuli
screening for the preferred substrate sequence of transglutaminase using a phage-displayed peptide library
stat3 cleavage by caspases
nox1-dependent reactive oxygen generation is regulated by rac1
iron-sulfur cluster biosynthesis
the wstf-snf2h chromatin remodeling complex interacts with several nuclear proteins in transcription
estrogen-occupied estrogen receptor represses cyclin g2 gene expression and recruits a repressor complex at the cyclin g2 promoter
analysis of nucleosome repositioning by yeast iswi and chd1 chromatin remodeling complexes
transcriptional profiling reveals novel markers of liver fibrogenesis
coxsackievirus protein 2bc blocks host cell apoptosis by inhibiting caspase-3
a “petite obligate“ mutant of saccharomyces cerevisiae
molecular cloning of the leishmania major udp-glucose pyrophosphorylase, functional characterization, and ligand binding analyses using nmr spectroscopy
14-3-3 isoforms are induced by aldosterone and participate in its regulation of epithelial sodium channels
a phosphoinositide 3-kinase-akt-nitric oxide-cgmp signaling pathway in stimulating platelet secretion and aggregation
keratin 20 serine 13 phosphorylation is a stress and intestinal goblet cell marker
on the mechanism of nucleosome assembly by histone chaperone nap1
akt regulates basal and induced processing of nf-b2 (p100) to p52
protein-tyrosine phosphatase (ptp) wedge domain peptides
amide hydrogen exchange reveals conformational changes in hsp70 chaperones important for allosteric regulation
bone morphogenetic protein-2 stimulates runx2 acetylation
disease-associated sequence variations congregate in a polyanion recognition patch on human factor h revealed in three-dimensional structure
collagen plays an active role in the aggregation of 2-microglobulin under physiopathological conditions of dialysis-related amyloidosis
fret analysis of in vivo dimerization by rna-editing enzymes
nucleophosmin regulates cell cycle progression and stress response in hematopoietic stem/progenitor cells
degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity
messenger-specific role for nicotinic acid adenine dinucleotide phosphate in neuronal differentiation
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