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a multifunctional acyl-acyl carrier protein desaturase from hedera helix l. (english ivy) can synthesize 16- and 18-carbon monoene and diene products
a critical control element for interleukin-4 memory expression in t helper lymphocytes
resistance to the antimicrobial peptide polymyxin requires myristoylation of escherichia coli and salmonella typhimurium lipid a
dramatic broadening of the substrate profile of the aeromonas hydrophila cpha metallo--lactamase by site-directed mutagenesis
transactivation-dependent and -independent regulation of p73 stability
determination of the functionality of common apoa5 polymorphisms
adenylate kinase of escherichia coli, a component of the phage t4 dntp synthetase complex
delayed mechanism for induction of -glutamylcysteine synthetase heavy subunit mrna stability by oxidative stress involving p38 mitogen-activated protein kinase sign..
phosphorylation of grk1 and grk7 by camp-dependent protein kinase attenuates their enzymatic activities
changes in ribosomal binding activity of eif3 correlate with increased translation rates during activation of t lymphocytes
the use of calnexin and calreticulin by cellular and viral glycoproteins
3‘-untranslated region of phosphoenolpyruvate carboxykinase mrna contains multiple instability elements that bind auf1
the evolutionarily related -barrel polypeptide transporters from pisum sativum and nostoc pcc7120 contain two distinct functional domains
leukocyte function-associated antigen 1-mediated adhesion stability is dynamically regulated through affinity and valency during bond formation with intercellular a..
physiological regulation of phospholipid methylation alters plasma homocysteine in mice
experimental and in silico analyses of glycolytic flux control in bloodstream form trypanosoma brucei
impact, a protein preferentially expressed in the mouse brain, binds gcn1 and inhibits gcn2 activation
a novel polymorphic cytochrome p450 formed by splicing of cyp3a7 and the pseudogene cyp3ap1
the pgr1 mutation in the rieske subunit of the cytochrome b6f complex does not affect pgr5-dependent cyclic electron transport around photosystem i
cyclooxygenase-2-mediated dna damage
a lipomannan variant with strong tlr-2-dependent pro-inflammatory activity in saccharothrix aerocolonigenes
cell adhesion status-dependent histone acetylation is regulated through intracellular contractility-related signaling activities
photoactivation perturbs the membrane-embedded contacts between sensory rhodopsin ii and its transducer
proteolytic excision of a repressive loop domain in tartrate-resistant acid phosphatase by cathepsin k in osteoclasts
role of the n-terminal domain of the human dmc1 protein in octamer formation and dna binding
the hydrophobic hinge region of rat dna polymerase is critical for substrate binding pocket geometry
tripeptide mimetics inhibit the 20 s proteasome by covalent bonding to the active threonines
phospholipase c-erk axis in vascular endothelial growth factor-induced eukaryotic initiation factor 4e phosphorylation and protein synthesis in renal epithelial cells
protein kinase c ii plays an essential role in dendritic cell differentiation and autoregulates its own expression
prostaglandin signaling in the renal collecting duct
nrf2 possesses a redox-insensitive nuclear export signal overlapping with the leucine zipper motif
diacylglycerol kinase regulates the secretion of lethal exosomes bearing fas ligand during activation-induced cell death of t lymphocytes
control of creb-binding protein signaling by nuclear fibroblast growth factor receptor-
cyclin d1 is not an immediate target of -catenin following apc loss in the intestine
molecular and pharmacological properties of a potent and selective novel nonsteroidal progesterone receptor agonist tanaproget
tudor domains bind symmetrical dimethylated arginines
crystal structure of isoaspartyl aminopeptidase in complex with l-aspartate
the non-catalytic chitin-binding protein cbp21 from serratia marcescens is essential for chitin degradation
dilated cardiomyopathy mutations in three thin filament regulatory proteins result in a common functional phenotype
functional characterization of jmjd2a, a histone deacetylase- and retinoblastoma-binding protein
checkpoint kinase 1 regulates diallyl trisulfide-induced mitotic arrest in human prostate cancer cells
the six zinc fingers of metal-responsive element binding transcription factor-1 form stable and quasi-ordered structures with relatively small differences in zinc a..
biosynthesis of vitamin b
the role and mechanism of diacylglycerol-protein kinase c1 signaling in melanogenesis by cryptococcus neoformans
dual roles of p2 purinergic receptors in insulin-stimulated leptin production and lipolysis in differentiated rat white adipocytes
generation and characterization of mutant cell lines defective in -secretase processing of notch and amyloid precursor protein
gene disruption of spred-2 causes dwarfism
the sterol-sensing domain of the niemann-pick c1 (npc1) protein regulates trafficking of low density lipoprotein cholesterol
crystal structure of phosphorylcholine esterase domain of the virulence factor choline-binding protein e from streptococcus pneumoniae
triadins are not triad-specific proteins
insights into interactions between the -helical region of the salmon calcitonin antagonists and the human calcitonin receptor using photoaffinity labeling
contributions of ca2+ to galectin-1-induced exposure of phosphatidylserine on activated neutrophils
fusogenic domains in herpes simplex virus type 1 glycoprotein h
biophysical characterization of the interaction domains and mapping of the contact residues in the xpf-ercc1 complex
ena/vasp proteins enhance actin polymerization in the presence of barbed end capping proteins
the cxcr1 and cxcr2 receptors form constitutive homo- and heterodimers selectively and with equal apparent affinities
structural and biochemical analysis reveal pirins to possess quercetinase activity
the unstructured n-terminal tail of parg modulates assembly of a quaternary nucleoprotein complex in transcription repression
a novel mechanism for the suppression of a voltage-gated potassium channel by glucose-dependent insulinotropic polypeptide
a phd finger motif in the c terminus of rag2 modulates recombination activity
a mechanism for assembly of complexes of vitronectin and plasminogen activator inhibitor-1 from sedimentation velocity analysis
tyrosine phosphorylation regulates the proteolytic activation of protein kinase c in dopaminergic neuronal cells
immortalized mouse mammary fibroblasts lacking dioxin receptor have impaired tumorigenicity in a subcutaneous mouse xenograft model
detection and identification of stable oligomeric protein complexes in escherichi coli inner membranes
alternative pre-mrna splicing governs expression of a conserved acidic transactivation domain in myocyte enhancer factor 2 factors of striated muscle and brain
global loss of set1-mediated h3 lys4 trimethylation is associated with silencing defects in saccharomyces cerevisiae
functional profiling of recombinant ns3 proteases from all four serotypes of dengue virus using tetrapeptide and octapeptide substrate libraries
oxidative stress-dependent structural and functional switching of a human 2-cys peroxiredoxin isotype ii that enhances hela cell resistance to h2o2-induced cell death
progressive accumulation of mitochondrial dna mutations and decline in mitochondrial function lead to -cell failure
insulin regulates the membrane arrival, fusion, and c-terminal unmasking of glucose transporter-4 via distinct phosphoinositides
fibronectin‘s central cell-binding domain supports focal adhesion formation and rho signal transduction
heteromeric protein complexes mediate zinc transport into the secretory pathway of eukaryotic cells
analysis of the large inactive p-tefb complex indicates that it contains one 7sk molecule, a dimer of hexim1 or hexim2, and two p-tefb molecules containing cdk9 pho..
inhibition of vascular permeability factor/vascular endothelial growth factor-mediated angiogenesis by the kruppel-like factor klf2
bcrc from bacillus subtilis acts as an undecaprenyl pyrophosphate phosphatase in bacitracin resistance
investigation of the lateral light-induced migration of photosystem ii light-harvesting proteins by nano-high performance liquid chromatography electrospray ionizat..
sp1/sp3-dependent regulation of human telomerase reverse transcriptase promoter activity by the bioactive sphingolipid ceramide
plant -glutamyl hydrolases and folate polyglutamates
role of upstream stimulatory factor phosphorylation in the regulation of the prostaglandin g/h synthase-2 promoter in granulosa cells
excitotoxic injury to mitochondria isolated from cultured neurons
cdna cloning and expression of the cardiac na+/ca2+ exchanger from mozambique tilapia (oreochromis mossambicus) reveal a teleost membrane transporter with mammalian..
the familial dementia bri2 gene binds the alzheimer gene amyloid- precursor protein and inhibits amyloid- production
extracellular trafficking of myocilin in human trabecular meshwork cells
coactivator-associated arginine methyltransferase 1, carm1, affects pre-mrna splicing in an isoform-specific manner
binding of pten to specific pdz domains contributes to pten protein stability and phosphorylation by microtubule-associated serine/threonine kinases
isoform-specific interaction of golgin-160 with the golgi-associated protein pist
characterization of a thermostable uvrd helicase and its participation in helicase-dependent amplification
antigenic properties of peptide mimotopes of hiv-1-associated carbohydrate antigens
compensation for a defective interaction of the hsp70 ssq1 with the mitochondrial fe-s cluster scaffold isu
an intramolecular interaction between sh2-kinase linker and kinase domain is essential for the catalytic activity of protein-tyrosine kinase-6
identification of ser153 in icl2 of the gonadotropin-releasing hormone (gnrh) receptor as a phosphorylation-independent site for inhibition of gq coupling
protein phosphatase 5 is a negative modulator of heat shock factor 1
regulation and surveillance of normal and 3‘-extended forms of the yeast aci-reductone dioxygenase mrna by rnase iii cleavage and exonucleolytic degradation
the modification of the conserved gxxxg motif of the membrane-spanning segment of subunit g destabilizes the supramolecular species of yeast atp synthase
a novel pathophysiological mechanism for osteoporosis suggested by an in vivo gene expression study of circulating monocytes
regulation of the pis1-encoded phosphatidylinositol synthase in saccharomyces cerevisiae by zinc
human t cell leukemia virus envelope binding and virus entry are mediated by distinct domains of the glucose transporter glut1
dna joint dependence of pol x family polymerase action in nonhomologous end joining
radical s-adenosylmethionine enzyme coproporphyrinogen iii oxidase hemn
the 3‘-azido group is not the primary determinant of 3‘-azido-3‘-deoxythymidine (azt) responsible for the excision phenotype of azt-resistant hiv-1
a cell-permeable, activity-based probe for protein and lipid kinases
the ca2+/calmodulin-dependent protein kinase kinases are amp-activated protein kinase kinases
a double mutation in the extracellular ca2+-sensing receptor‘s venus flytrap domain that selectively disables l-amino acid sensing
the crystal structure of mlc, a global regulator of sugar metabolism in escherichia coli
human serum igm glycosylation
architecture of the human ndc80-hec1 complex, a critical constituent of the outer kinetochore
mutant protein kinase c found in spinocerebellar ataxia type 14 is susceptible to aggregation and causes cell death
std and trnoesy nmr studies on the conformation of the oncogenic protein -catenin containing the phosphorylated motif dpsgxxps bound to the -trcp protein
identification of the ankyrin repeat proteins ankra and rfxank as novel partners of class iia histone deacetylases
a novel phospholipase c, plc2, is a neuron-specific isozyme
varicella-zoster virus ie63 protein phosphorylation by roscovitine-sensitive cyclin-dependent kinases modulates its cellular localization and activity
functional homology among human and fission yeast cdc14 phosphatases
mutations in mto2 related to trna modification impair mitochondrial gene expression and protein synthesis in the presence of a paromomycin resistance mutation in mi..
nuclear import and export signals in control of nrf2
the apical targeting signal of the p2y2 receptor is located in its first extracellular loop
structural basis for interaction between the ubp3 deubiquitinating enzyme and its bre5 cofactor
the calcium-binding protein s100a2 interacts with p53 and modulates its transcriptional activity
superoxide dismutase/catalase mimetics are neuroprotective against selective paraquat-mediated dopaminergic neuron death in the substantial nigra
trka induces apoptosis of neuroblastoma cells and does so via a p53-dependent mechanism
epitope mapping of monoclonal antibody to integrin l 2 hybrid domain suggests different requirements of affinity states for intercellular adhesion molecules (icam)-..
key role of conserved histidines in recombinant mouse -carotene 15,15‘-monooxygenase-1 activity
regulation of homeodomain-interacting protein kinase 2 (hipk2) effector function through dynamic small ubiquitin-related modifier-1 (sumo-1) modification
nibp, a novel nik and ikk-binding protein that enhances nf-b activation
myd88 is pivotal for the early inflammatory response and subsequent bacterial clearance and survival in a mouse model of chlamydia pneumoniae pneumonia
recoverin undergoes light-dependent intracellular translocation in rod photoreceptors
induction of nr4a orphan nuclear receptor expression in macrophages in response to inflammatory stimuli
increased levels of inositol hexakisphosphate (insp6) protect hek293 cells from tumor necrosis factor - and fas-induced apoptosis
crystal structures of the hiv-1 inhibitory cyanobacterial protein mvl free and bound to man3glcnac
a pest deletion mutant of abca1 shows impaired internalization and defective cholesterol efflux from late endosomes
cdk2-dependent inhibition of p21 stability via a c-terminal cyclin-binding motif
structural basis for autoinhibition and mutational activation of eukaryotic initiation factor 2 protein kinase gcn2
identification of s-hydroxylysyl-methionine as the covalent cross-link of the noncollagenous (nc1) hexamer of the 112 collagen iv network
methionine sulfoxide and proteolytic cleavage contribute to the inactivation of cathepsin g by hypochlorous acid
n-methyl-d-aspartate receptor subtype mediated bidirectional control of p38 mitogen-activated protein kinase
processing of viral dna ends channels the hiv-1 integration reaction to concerted integration
the auucu repeats responsible for spinocerebellar ataxia type 10 form unusual rna hairpins
the p53-induced gene-6 (proline oxidase) mediates apoptosis through a calcineurin-dependent pathway
biphasic functions of the kinase-defective ephb6 receptor in cell adhesion and migration
down-regulation of 7sl rna expression and impairment of vesicular protein transport pathways by leishmania infection of macrophages
identification of topbp1 as a c-abl-interacting protein and a repressor for c-abl expression
myosin x is a high duty ratio motor
thrombin functions through its rgd sequence in a non-canonical conformation
a role for glycogen synthase kinase-3 in the mammalian circadian clock
cardiolipin is essential for organization of complexes iii and iv into a supercomplex in intact yeast mitochondria
ras-erk mapk cascade regulates gata3 stability and th2 differentiation through ubiquitin-proteasome pathway
microtubule regulation of n-methyl-d-aspartate receptor channels in neurons
the proximal carboxyl-terminal domains of adamts13 determine substrate specificity and are all required for cleavage of von willebrand factor
depolarization of neural cells induces transcription of the down syndrome critical region 1 isoform 4 via a calcineurin/nuclear factor of activated t cells-dependen..
the redox state of the baculovirus single-stranded dna-binding protein lef-3 regulates its dna binding, unwinding, and annealing activities
the isoprenoid substrate specificity of isoprenylcysteine carboxylmethyltransferase
role of sphingosine kinase 2 in cell migration toward epidermal growth factor
a high throughput screen to identify substrates for the ubiquitin ligase rsp5
the sarcolemmal calcium pump inhibits the calcineurin/nuclear factor of activated t-cell pathway via interaction with the calcineurin a catalytic subunit
organic cation permeation through the channel formed by polycystin-2
physical and functional mapping of the replication protein a interaction domain of the werner and bloom syndrome helicases
glycosylation of eag1 (kv10.1) potassium channels
multiple turnover transfer of [2fe2s] clusters by the iron-sulfur cluster assembly scaffold proteins iscu and isca
protein phosphatase 2a regulates estrogen receptor (er) expression through modulation of er mrna stability
cloning of the rat pyruvate dehydrogenase kinase 4 gene promoter
mapk-mediated phosphorylation of gata-1 promotes bcl-xl expression and cell survival
myristic acid stimulates endothelial nitric-oxide synthase in a cd36- and an amp kinase-dependent manner
tbp-taf complex sl1 directs rna polymerase i pre-initiation complex formation and stabilizes upstream binding factor at the rdna promoter
endogenous trpc1, trpc3, and trpc7 proteins combine to form native store-operated channels in hek-293 cells
ccr5 n-terminal region plays a critical role in hiv-1 inhibition by toxoplasma gondii-derived cyclophilin-18
caspase-12 and caspase-4 are not required for caspase-dependent endoplasmic reticulum stress-induced apoptosis
identification of two critical amino acid residues of the severe acute respiratory syndrome coronavirus spike protein for its variation in zoonotic tropism transiti..
a proteoglycan undergoes different modifications en route to the apical and basolateral surfaces of madin-darby canine kidney cells
hepatitis c virus ns2/3 processing is required for ns3 stability and viral rna replication
molecular mechanism for divergent regulation of cav1.2 ca2+ channels by calmodulin and ca2+-binding protein-1
flow activates erk1/2 and endothelial nitric oxide synthase via a pathway involving pecam1, shp2, and tie2
h19 mrna-like noncoding rna promotes breast cancer cell proliferation through positive control by e2f1
cd47 augments fas/cd95-mediated apoptosis
the tetra-aspartate motif in the activation peptide of human cationic trypsinogen is essential for autoactivation control but not for enteropeptidase recognition
human t-lymphotropic virus, type 1, tax protein triggers microtubule reorientation in the virological synapse
androgen receptor gene knockout male mice exhibit impaired cardiac growth and exacerbation of angiotensin ii-induced cardiac fibrosis
human keratinocytes release atp and utilize three mechanisms for nucleotide interconversion at the cell surface
cd2-associated protein (cd2ap) expression in podocytes rescues lethality of cd2ap deficiency
time-dependent changes in the denatured state(s) influence the folding mechanism of an all -sheet protein
unraveling the mechanism of a potent transcriptional activator
specification of the direction of adhesive signaling by the integrin cytoplasmic domain
conserved structural and functional control of n-methyl-d-aspartate receptor gating by transmembrane domain m3
differential regulation of dentin sialophosphoprotein expression by runx2 during odontoblast cytodifferentiation
cyclin d1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanism
effect of inhibition of the bc1 complex on gene expression profile in yeast
dna adduct bypass polymerization by sulfolobus solfataricus dna polymerase dpo
interdomain communication in hepatitis c virus polymerase abolished by small molecule inhibitors bound to a novel allosteric site
aberrantly increased hydrophobicity shared by mutants of cu,zn-superoxide dismutase in familial amyotrophic lateral sclerosis
c-jun/activator protein-1 mediates interleukin-1-induced dedifferentiation but not cyclooxygenase-2 expression in articular chondrocytes
the conformation, location, and dynamic properties of the endocannabinoid ligand anandamide in a membrane bilayer
mutations remote from the human gonadotropin-releasing hormone (gnrh) receptor-binding sites specifically increase binding affinity for gnrh ii but not gnrh i
the homeobox protein msx2 interacts with tax oncoproteins and represses their transactivation activity
structure and properties of the c-terminal domain of insulin-like growth factor-binding protein-1 isolated from human amniotic fluid
repulsive guidance molecule (rgma), a dragon homologue, is a bone morphogenetic protein co-receptor
mechanisms for the apoptosis of small cell lung cancer cells induced by anti-gd2 monoclonal antibodies
energetics of substrate binding and catalysis by class 1 (glycosylhydrolase family 47) -mannosidases involved in n-glycan processing and endoplasmic reticulum quali..
wave2 signaling mediates invasion of polarized epithelial cells by salmonella typhimurium
vascular endothelial growth factor receptor-
forkhead transcription factors inhibit vascular smooth muscle cell proliferation and neointimal hyperplasia
the retinal g protein-coupled receptor (rgr) enhances isomerohydrolase activity independent of light
heat shock protein 27 is the major differentially phosphorylated protein involved in renal epithelial cellular stress response and controls focal adhesion organizat..
the nipah virus fusion protein is cleaved within the endosomal compartment
hoxb13 up-regulates transglutaminase activity and drives terminal differentiation in an epidermal organotypic model
functional significance of type 1 insulin-like growth factor-mediated nuclear translocation of the insulin receptor substrate-1 and -catenin
the small gtpase rala controls exocytosis of large dense core secretory granules by interacting with arf6-dependent phospholipase d1
µ-calpain regulates receptor activator of nf-b ligand (rankl)-supported osteoclastogenesis via nf-b activation in raw 264.7 cells
structural basis for non-cognate amino acid discrimination by the valyl-trna synthetase editing domain
accelerated glucose intolerance, nephropathy, and atherosclerosis in prostaglandin d2 synthase knock-out mice
interactions of the n-terminal domain of ribosomal protein l11 with thiostrepton and rrna
fas binding to calmodulin regulates apoptosis in osteoclasts
the farnesoid x receptor modulates hepatic carbohydrate metabolism during the fasting-refeeding transition
saccharomyces cerevisiae dna polymerase
identification of vascular endothelial growth factor receptor-binding protein in the venom of eastern cottonmouth
vascular endothelial growth factor induction by prostaglandin e2 in human airway smooth muscle cells is mediated by e prostanoid ep2/ep4 receptors and sp-1 transcri..
protofibril formation of amyloid -protein at low ph via a non-cooperative elongation mechanism
-synuclein alters proteasome function, protein synthesis, and stationary phase viability
bap31 and its caspase cleavage product regulate cell surface expression of tetraspanins and integrin-mediated cell survival
set8 recognizes the sequence rhrk20vlrdn within the n terminus of histone h4 and mono-methylates lysine 20
the acute box cis-element in human heavy ferritin mrna 5‘-untranslated region is a unique translation enhancer that binds poly(c)-binding proteins
dual oxidase-2 has an intrinsic ca2+-dependent h2o2-generating activity
protein kinase a-dependent phosphorylation of lutheran/basal cell adhesion molecule glycoprotein regulates cell adhesion to laminin 5
the yoeb toxin is a folded protein that forms a physical complex with the unfolded yefm antitoxin
n1-aminopropylagmatine, a new polyamine produced as a key intermediate in polyamine biosynthesis of an extreme thermophile, thermus thermophilus
isolation of tak-779-resistant hiv-1 from an r5 hiv-1 gp120 v3 loop library
ubiquitination of keap1, a btb-kelch substrate adaptor protein for cul3, targets keap1 for degradation by a proteasome-independent pathway
scission of the lactyl ether bond of n-acetylmuramic acid by escherichia coli “etherase“
a novel -conotoxin, peia, cloned from conus pergrandis, discriminates between rat 910 and 7 nicotinic cholinergic receptors
tumor necrosis factor- convertase (adam17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (sars-cov) receptor, angioten..
loss of the von hippel lindau tumor suppressor disrupts iron homeostasis in renal carcinoma cells
superoxide radical formation by pure complex i (nadh:ubiquinone oxidoreductase) from yarrowia lipolytica
identification of a crucial histidine involved in metal transport activity in the arabidopsis cation/h+ exchanger cax1
interaction with pdzk1 is required for expression of organic anion transporting protein 1a1 on the hepatocyte surface
abcg1 redistributes cell cholesterol to domains removable by high density lipoprotein but not by lipid-depleted apolipoproteins
regions of drosophila notch that contribute to ligand binding and the modulatory influence of fringe
functionally independent au-rich sequence motifs regulate kc (cxcl1) mrna
sequential phosphorylation mediates receptor- and kinase-induced inhibition of trek-1 background potassium channels
jlp associates with kinesin light chain 1 through a novel leucine zipper-like domain
unloading induces osteoblastic cell suppression and osteoclastic cell activation to lead to bone loss via sympathetic nervous system
nadph oxidase restrains the matrix metalloproteinase activity of macrophages
specificity of protein interactions mediated by brct domains of the xrcc1 dna repair protein
a leptospira interrogans enzyme with similarity to yeast ste14p that methylates the 1-phosphate group of lipid a
renal carcinoma-associated transcription factors tfe3 and tfeb are leukemia inhibitory factor-responsive transcription activators of e-cadherin
characterization of the gs regulator cysteine string protein
cleavage of p21/waf1/cip1 by proteinase 3 modulates differentiation of a monocytic cell line
enhanced proliferative potential of hematopoietic cells expressing degradation-resistant c-myb mutants
role of the executioner caspases during lens development
nad+-dependent dna ligase (rv3014c) from mycobacterium tuberculosis
interaction of the ty3 reverse transcriptase thumb subdomain with template-primer
“natively unfolded“ vpg is essential for sesbania mosaic virus serine protease activity
ubiquitination of p27kip1 requires physical interaction with cyclin e and probable phosphate recognition by skp2
the c-terminal domain of the nucleotide-binding domain protein wzt determines substrate specificity in the atp-binding cassette transporter for the lipopolysacchari..
energetic mapping of transition state analogue interactions with human and plasmodium falciparum purine nucleoside phosphorylases
evidence for a granule targeting sequence within platelet factor 4
activation of ataxia telangiectasia-mutated dna damage checkpoint signal transduction elicited by herpes simplex virus infection
domain swapping between enterococcus faecalis fabn and fabz proteins localizes the structural determinants for isomerase activity
location of the coenzyme binding site in the porcine mitochondrial nadp-dependent isocitrate dehydrogenase
a role of p73 in mitotic exit
stabilization of non-productive conformations underpins rapid electron transfer to electron-transferring flavoprotein
identification and characterization of human archaemetzincin-1 and -2, two novel members of a family of metalloproteases widely distributed in archaea
g12 interaction with snap induces ve-cadherin localization at endothelial junctions and regulates barrier function
reactivation of mutant p53 and induction of apoptosis in human tumor cells by maleimide analogs
ligand-induced dimer-tetramer transition during the activation of the cell surface epidermal growth factor receptor-a multidimensional microscopy analysis
keratin 8 phosphorylation by protein kinase c regulates shear stress-mediated disassembly of keratin intermediate filaments in alveolar epithelial cells
expression of scavenger receptors in glial cells
connexin 43 interacts with zona occludens-1 and -2 proteins in a cell cycle stage-specific manner
persistent nicotine treatment potentiates amplification of the dihydrofolate reductase gene in rat lung epithelial cells as a consequence of ras activation
thioredoxin reductase system mediates iron binding in isca and iron delivery for the iron-sulfur cluster assembly in iscu
structure of unliganded grp94, the endoplasmic reticulum hsp9
role of conformational heterogeneity in domain swapping and adapter function of the cks proteins
2 subunit contribution to 4/7 -conotoxin binding to the nicotinic acetylcholine receptor
functional metabotropic glutamate receptors on nuclei from brain and primary cultured striatal neurons
extracellular matrix proteoglycans control the fate of bone marrow stromal cells
the zebrafish retinol dehydrogenase, rdh1l, is essential for intestinal development and is regulated by the tumor suppressor adenomatous polyposis coli
structural elucidation of chalcone reductase and implications for deoxychalcone biosynthesis
structure-function analysis of the three domains of ruvb dna motor protein
identification of the amino acid residue of cyp27b1 responsible for binding of 25-hydroxyvitamin d3 whose mutation causes vitamin d-dependent rickets type 1
bcl-2 positively regulates sox9-dependent chondrocyte gene expression by suppressing the mek-erk1/2 signaling pathway
fibrillin-1 interactions with heparin
membrane fusion induced by neuronal snares transits through hemifusion
proteasome-mediated degradation of stat1 following infection of macrophages with leishmania donovani
disruption of the coenzyme binding site and dimer interface revealed in the crystal structure of mitochondrial aldehyde dehydrogenase “asian“ variant
protein import, replication, and inheritance of a vestigial mitochondrion
tumor cell pseudopodial protrusions
siderophore transport through escherichia coli outer membrane receptor fhua with disulfide-tethered cork and barrel domains
structural and chemical requirements for histidine phosphorylation by the chemotaxis kinase chea
the crystal structure of the plexin-semaphorin-integrin domain/hybrid domain/i-egf1 segment from the human integrin 2 subunit at 1.8-å resolution
myosin v from drosophila reveals diversity of motor mechanisms within the myosin v family
p300 regulates p63 transcriptional activity
ca2+/calmodulin-dependent protein kinase ii is an essential mediator in the coordinated regulation of electrocyte ca2+-atpase by calmodulin and protein kinase a
transcription-dependent association of multiple positive transcription elongation factor units to a hexim multimer
activation of nf-b by extracellular matrix is involved in spreading and glucose-stimulated insulin secretion of pancreatic beta cells
identification of conserved prolyl residue important for transport activity and the substrate specificity range of yeast plasma membrane na+/h+ antiporters
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