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interleukin-12-induced interferon- production by human peripheral blood t cells is regulated by mammalian target of rapamycin (mtor)
insulin-induced -arrestin1 ser-412 phosphorylation is a mechanism for desensitization of erk activation by gi-coupled receptors
characterization of the alzheimer‘s disease-associated clac protein and identification of an amyloid -peptide-binding site
characterization of a second arabidopsis thaliana prolyl 4-hydroxylase with distinct substrate specificity
c-jun n-terminal kinase 3 deficiency protects neurons from axotomy-induced death in vivo through mechanisms independent of c-jun phosphorylation
stat5b-mediated growth hormone signaling is organized by highly dynamic microtubules in hepatic cells
the role of an activating peptide in protease-mediated suicide of escherichia coli k12
myc antagonizes ras-mediated growth arrest in leukemia cells through the inhibition of the ras-erk-p21cip1 pathway
cyclin-dependent kinase 9 is required for tumor necrosis factor--stimulated matrix metalloproteinase-9 expression in human lung adenocarcinoma cells
role of serine 10 phosphorylation in p27 stabilization revealed by analysis of p27 knock-in mice harboring a serine 10 mutation
identification and characterization of a novel vitamin b12 (cobalamin) biosynthetic enzyme (cobz) from rhodobacter capsulatus, containing flavin, heme, and fe-s cof..
integrin-mediated adhesion and soluble ligand binding stabilize cox-2 protein levels in endothelial cells by inducing expression and preventing degradation
mutational analysis of the -1 repeat of the cardiac na+-ca2+ exchanger
the v-atpase subunit c binds to polymeric f-actin as well as to monomeric g-actin and induces cross-linking of actin filaments
mnt1p and mnt2p of candida albicans are partially redundant -1,2-mannosyltransferases that participate in o-linked mannosylation and are required for adhesion and v..
histone h2a and spt10 cooperate to regulate induction and autoregulation of the cup1 metallothionein
distinct molecular mechanisms for agonist peptide binding to types a and b cholecystokinin receptors demonstrated using fluorescence spectroscopy
ric-3 promotes functional expression of the nicotinic acetylcholine receptor 7 subunit in mammalian cells
peptide yy and neuropeptide y induce villin expression, reduce adhesion, and enhance migration in small intestinal cells through the regulation of cd63, matrix meta..
the snare proteins snap-25 and snap-23 display different affinities for lipid rafts in pc12 cells
activation of peroxisome proliferator-activated receptor increases the expression and activity of microsomal triglyceride transfer protein in the liver
reconstitution of regulated phosphorylation of fcri by a lipid raft-excluded protein-tyrosine phosphatase
role for protein kinase c (pkc) in tcr/cd28-mediated signaling through the canonical but not the non-canonical pathway for nf-b activation
calcium-binding crystallins from yersinia pestis
a novel repressive e2f6 complex containing the polycomb group protein, epc1, that interacts with ezh2 in a proliferation-specific manner
assignment of the binding site for haptoglobin on apolipoprotein a-i
ataxia telangiectasia mutated (atm) and atm and rad3-related protein exhibit selective target specificities in response to different forms of dna damage
dna topoisomerase ii poison tas-103 transactivates gc-box-dependent transcription via acetylation of sp1
mutant copper-zinc superoxide dismutase binds to and destabilizes human low molecular weight neurofilament mrna
kinetics of nucleotide incorporation opposite dna bulky guanine n2 adducts by processive bacteriophage t7 dna polymerase (exonuclease-) and hiv-1 reverse transcript..
a role for rat inositol polyphosphate kinases ripk2 and ripk1 in inositol pentakisphosphate and inositol hexakisphosphate production in rat-1 cells
distinct roles for the and subunits in the functions of integrin m2
extended neck regions stabilize tetramers of the receptors dc-sign and dc-signr
novel mechanism of interaction of p85 subunit of phosphatidylinositol 3-kinase and erbb3 receptor-derived phosphotyrosyl peptides
aminopeptidase n (cd13) is a molecular target of the cholesterol absorption inhibitor ezetimibe in the enterocyte brush border membrane
role of the sc c terminus in transcriptional activation and e(spl) repressor recruitment
membrane type 1-matrix metalloproteinase is regulated by chemokines monocyte-chemoattractant protein-1/ccl2 and interleukin-8/cxcl8 in endothelial cells during angi..
suppression of wild-type rhodopsin maturation by mutants linked to autosomal dominant retinitis pigmentosa
altered interaction and expression of proteins involved in neurosecretion in scrapie-infected gt1-1 cells
pdilt, a divergent testis-specific protein disulfide isomerase with a non-classical sxxc motif that engages in disulfide-dependent interactions in the endoplasmic r..
direct evidence that neural cell adhesion molecule (ncam) polysialylation increases intermembrane repulsion and abrogates adhesion
combinatorial transcription of herpes simplex virus and varicella zoster virus immediate early genes is strictly determined by the cellular coactivator hcf-1
67-kda laminin receptor promotes internalization of cytotoxic necrotizing factor 1-expressing escherichia coli k1 into human brain microvascular endothelial cells
monoallelic expression and asynchronous replication of p120 catenin in mouse and human cells
functional characterization in vitro of all two-component signal transduction systems from escherichia coli
phospholipase c2 binds to and inhibits phospholipase c1
the role of plasmodium falciparum food vacuole plasmepsins
structure of the dimeric pufx-containing core complex of rhodobacter blasticus by in situ atomic force microscopy
phosphorylation and sulfation of oligosaccharide substrates critically influence the activity of human 1,4-galactosyltransferase 7 (galt-i) and 1,3-glucuronosyltran..
varied mechanisms underlie the free sialic acid storage disorders
the stem cell pluripotency factor nanog activates transcription with two unusually potent subdomains at its c terminus
the structure of ralf, an adp-ribosylation factor guanine nucleotide exchange factor from legionella pneumophila, reveals the presence of a cap over the active site
use of photoaffinity labeling and site-directed mutagenesis for identification of the key residue responsible for extraordinarily high affinity binding of ucn-01 in..
structure of the ubiquitin hydrolase uch-l3 complexed with a suicide substrate
the plasma membrane q-snare syntaxin 2 enters the zymogen granule membrane during exocytosis in the pancreatic acinar cell
clostridium difficile toxin a induces expression of the stress-induced early gene product rhob
direct voltage control of signaling via p2y1 and other gq-coupled receptors
additivity in effects of vitronectin and monoclonal antibodies against -helix f of plasminogen activator inhibitor-1 on its reactions with target proteinases
the adenovirus e4orf6 protein inhibits dna double strand break repair and radiosensitizes human tumor cells in an e1b-55k-independent manner
arabidopsis haf2 gene encoding tata-binding protein (tbp)-associated factor taf1, is required to integrate light signals to regulate gene expression and growth
sumoylation of mitf and its related family members tfe3 and tfeb
tcf-4 mediates cell type-specific regulation of proglucagon gene expression by -catenin and glycogen synthase kinase-3
differential protein mobility of the -aminobutyric acid, type a, receptor and subunit channel-lining segments
four na+/h+ exchanger isoforms are distributed to golgi and post-golgi compartments and are involved in organelle ph regulation
modulation of yersinia type three secretion system by the s1 domain of polynucleotide phosphorylase
porcine dentin sialoprotein is a proteoglycan with glycosaminoglycan chains containing chondroitin 6-sulfate
molecular basis for a direct interaction between the syk protein-tyrosine kinase and phosphoinositide 3-kinase
mapping the 1 gabac receptor agonist binding pocket
pathological prion protein exposure switches on neuronal mitogen-activated protein kinase pathway resulting in microglia recruitment
analysis of transport activity of arabidopsis sugar alcohol permease homolog atplt5
angiotensin ii and epidermal growth factor induce cyclooxygenase-2 expression in intestinal epithelial cells through small gtpases using distinct signaling pathways
structural dissection of a highly knotted peptide reveals minimal motif with antimicrobial activity
evolutionarily conserved multiple c2 domain proteins with two transmembrane regions (mctps) and unusual ca2+ binding properties
severe acute respiratory syndrome coronavirus 3c-like proteinase n terminus is indispensable for proteolytic activity but not for enzyme dimerization
inositol hexakisphosphate kinase-2, a physiologic mediator of cell death
characterization of the interaction between retinoic acid receptor/retinoid x receptor (rar/rxr) heterodimers and transcriptional coactivators through structural an..
mitochondria-specific rna-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial trnas
the conserved immunoglobulin domain controls the subcellular localization of the homophilic adhesion receptor protein-tyrosine phosphatase µ
apoptosis and survival of osteoblast-like cells are regulated by surface attachment
dynamic gata factor interplay at a multicomponent regulatory region of the gata-2 locus
a stable proteinaceous structure in the territory of inactive x chromosomes
clc-3 chloride channels facilitate endosomal acidification and chloride accumulation
real-time monitoring of the pde2 activity of live cells
an intermediate form of adp-f-actin
akt2 phosphorylates ezrin to trigger nhe3 translocation and activation
stimulus-specific induction of a novel nuclear factor-b regulator, ib-, via toll/interleukin-1 receptor is mediated by mrna stabilization
determination of selectivity and efficacy of fatty acid synthesis inhibitors
an inhibitor of the f1 subunit of atp synthase (if1) modulates the activity of angiostatin on the endothelial cell surface
the membrane-associated inhibitor of apoptosis protein, bruce/apollon, antagonizes both the precursor and mature forms of smac and caspase-9
orexin-a-induced ca2+ entry
serine racemase modulates intracellular d-serine levels through an,-elimination activity
regulation of nf-b2 p100 processing by its cis-acting domain
novel parathyroid hormone (pth) antagonists that bind to the juxtamembrane portion of the pth/pth-related protein receptor
dephosphorylation of tau by protein phosphatase
tryptophan insertion mutagenesis of liver fatty acid-binding protein
role of tyrosine 441 of interferon- receptor subunit 1 in socs-1-mediated attenuation of stat1 activation
extracellular atp-induced proliferation of adventitial fibroblasts requires phosphoinositide 3-kinase, akt, mammalian target of rapamycin, and p70 s6 kinase signali..
adam10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx
nucleosome assembly protein 1 exchanges histone h2a-h2b dimers and assists nucleosome sliding
ubiquitination of the peroxisomal targeting signal type 1 receptor, pex5p, suggests the presence of a quality control mechanism during peroxisomal matrix protein im..
the pathway for the production of inositol hexakisphosphate in human cells
single amino acid substitutions in procollagen vii affect early stages of assembly of anchoring fibrils
klf11-mediated repression antagonizes sp1/sterol-responsive element-binding protein-induced transcriptional activation of caveolin-1 in response to cholesterol sign..
regulation of atp-sensitive potassium channel subunit kir6.2 expression in rat intestinal insulin-producing progenitor cells
design of soluble recombinant t cell receptors for antigen targeting and t cell inhibition
interaction between the nh2-terminal domain of eif4a and the central domain of eif4g modulates rna-stimulated atpase activity
studies on the n-glycosylation of the subunits of oligosaccharyl transferase in saccharomyces cerevisiae
a direct interaction between cdc42 and vesicle-associated membrane protein 2 regulates snare-dependent insulin exocytosis
adhesion stimulates direct pak1/erk2 association and leads to erk-dependent pak1 thr212 phosphorylation
ph-dependent interactions of the carboxyl-terminal helix of steroidogenic acute regulatory protein with synthetic membranes
rna structural rearrangement via unwinding and annealing by the cyanobacterial rna helicase, crhr
reconstitution of gdp-mannose transport activity with purified leishmania lpg2 protein in liposomes
residues 10-18 within the c5a receptor n terminus compose a binding domain for chemotaxis inhibitory protein of staphylococcus aureus
phosphorylation-independent stabilization of p27kip1 by the phosphoinositide 3-kinase pathway in glioblastoma cells
structure-activity relationships of diastereomeric lysine ring size analogs of the antimicrobial peptide gramicidin s
a sequence within the first transmembrane domain of pen-2 is critical for pen-2-mediated endoproteolysis of presenilin 1
regulated association of protein kinase b/akt with breast tumor kinase
differential regulation of sterol regulatory element-binding protein 1c transcriptional activity by insulin and liver x receptor during liver development
ectopic expression of p73, but not p73, suppresses myogenic differentiation
nuclear calpain regulates ca2+-dependent signaling via proteolysis of nuclear ca2+/calmodulin-dependent protein kinase type iv in cultured neurons
differential effects of modification of membrane cholesterol and sphingolipids on the conformation, function, and trafficking of the g protein-coupled cholecystokin..
characterization of a novel type of endogenous activator of soluble guanylyl cyclase
bimodal regulation of the human h1 histamine receptor by g protein-coupled receptor kinase 2
receptor-selective mutants of apoptosis-inducing ligand 2/tumor necrosis factor-related apoptosis-inducing ligand reveal a greater contribution of death receptor (d..
second-site suppression of a nonfunctional mutation within the leishmania donovani inosine-guanosine transporter
rab13 mediates the continuous endocytic recycling of occludin to the cell surface
the ca2+ channel 2-1 subunit determines ca2+ current kinetics in skeletal muscle but not targeting of 1s or excitation-contraction coupling
human immunodeficiency virus protease inhibitors accumulate into cultured human adipocytes and alter expression of adipocytokines
expression cloning and demonstration of enterococcus faecalis lipoamidase (pyruvate dehydrogenase inactivase) as a ser-ser-lys triad amidohydrolase
neurotrophin-dependent tyrosine phosphorylation of ras guanine-releasing factor 1 and associated neurite outgrowth is dependent on the hike domain of trka
microtubule-associated protein 1s, a short and ubiquitously expressed member of the microtubule-associated protein 1 family
mitochondrial release of pro-apoptotic proteins
a structural basis of equisetum arvense ferredoxin isoform ii producing an alternative electron transfer with ferredoxin-nadp+ reductase
insulin receptor substrate-2 proteasomal degradation mediated by a mammalian target of rapamycin (mtor)-induced negative feedback down-regulates protein kinase b-me..
hoxa5-twist interaction alters p53 homeostasis in breast cancer cells
a novel c-terminal motif is necessary for the export of the vasopressin v1b/v3 receptor to the plasma membrane
dkk-1-derived synthetic peptides and lithium chloride for the control and recovery of adult stem cells from bone marrow
the key role of protein flexibility in modulating ige interactions
the yeast mitochondrial citrate transport protein
fluctuations of intracellular iron modulate elastin production
a unique hydrophobic cluster near the active site contributes to differences in borrelidin inhibition among threonyl-trna synthetases
neuroprotective effects of phenylbutyrate in the n171-82q transgenic mouse model of huntington‘s disease
activation of the discoidin domain receptor 2 induces expression of matrix metalloproteinase 13 associated with osteoarthritis in mice
conformational her-2/neu b-cell epitope peptide vaccine designed to incorporate two native disulfide bonds enhances tumor cell binding and antitumor activities
identification of a region of fast skeletal troponin t required for stabilization of the coiled-coil formation with troponin i
family 6 carbohydrate binding modules recognize the non-reducing end of -1,3-linked glucans by presenting a unique ligand binding surface
structural basis for the inactivity of human blood group o2 glycosyltransferase
viability of escherichia coli topa mutants lacking dna topoisomerase i
effects of depletion of creb-binding protein on c-myc regulation and cell cycle g1-s transition
production of infectious sivagm from human cells requires functional inactivation but not viral exclusion of human apobec3g
localization of nitration and chlorination sites on apolipoprotein a-i catalyzed by myeloperoxidase in human atheroma and associated oxidative impairment in abca1-d..
specific structural features of heparan sulfate proteoglycans potentiate neuregulin-1 signaling
developmental abnormalities of myelin basic protein expression in fyn knock-out brain reveal a role of fyn in posttranscriptional regulation
mimosine attenuates serine hydroxymethyltransferase transcription by chelating zinc
the repressor element silencing transcription factor (rest)-mediated transcriptional repression requires the inhibition of sp1
interaction of checkpoint proteins hus1/rad1/rad9 with dna base excision repair enzyme muty homolog in fission yeast, schizosaccharomyces pombe
a primer-dependent polymerase function of pseudomonas aeruginosa atp-dependent dna ligase (ligd)
evi1 abrogates interferon- response by selectively blocking pml induction
two-dimensional transcriptome analysis in chemostat cultures
poly(adp-ribose) polymerase-1 is a negative regulator of hiv-1 transcription through competitive binding to tar rna with tat·positive transcription elongation fact..
determination of the functional unit of the cystic fibrosis transmembrane conductance regulator chloride channel
crystal structure of the human cytosolic sialidase neu
prostaglandin e2 regulates the complement inhibitor cd55/decay-accelerating factor in colorectal cancer
signal-anchored proteins follow a unique insertion pathway into the outer membrane of mitochondria
the 1.8-å crystal structure of human tear lipocalin reveals an extended branched cavity with capacity for multiple ligands
the c-terminal residues in the alpha-interacting domain (aid) helix anchor cav subunit interaction and modulation of cav2.3 channels
triacylglycerol is synthesized in a specific subclass of caveolae in primary adipocytes
controlling the regiospecific oxidation of aromatics via active site engineering of toluene para-monooxygenase of ralstonia pickettii pko1
nuclear-cytoplasmic shuttling of the oncogenic mouse unp/usp4 deubiquitylating enzyme
crystal structure of mouse carnitine octanoyltransferase and molecular determinants of substrate selectivity
epidermal peroxisome proliferator-activated receptor as a target for ultraviolet b radiation
crystal structure of an atpase-active form of rad51 homolog from methanococcus voltae
[ca2+]i signaling between mitochondria and endoplasmic reticulum in neurons is regulated by microtubules
in vivo and in vitro analysis of cardiac troponin i phosphorylation
the type i hsp40 zinc finger-like region is required for hsp70 to capture non-native polypeptides from ydj1
trapping prion protein in the endoplasmic reticulum impairs prpc maturation and prevents prpsc accumulation
methionine adenosyltransferase:adrenergic-camp mechanism regulates a daily rhythm in pineal expression
cell- and ligand-specific regulation of promoters containing activator protein-1 and sp1 sites by estrogen receptors and
the interferon-inducible p204 protein acts as a transcriptional coactivator of cbfa1 and enhances osteoblast differentiation
regiospecificity determinants of human heme oxygenase
identification of new genes regulated by the crt1 transcription factor, an effector of the dna damage checkpoint pathway in saccharomyces cerevisiae
the sec14 homology domain regulates the cellular distribution and transforming activity of the rho-specific guanine nucleotide exchange factor dbs
the transcription factor nfat3 mediates neuronal survival
a dynamic zinc redox switch
a targeted mutation of nkd1 impairs mouse spermatogenesis
differential regulation of g protein subunit trafficking by mono- and polyubiquitination
staphylococcus aureus isdg and isdi, heme-degrading enzymes with structural similarity to monooxygenases
degradation of myod mediated by the scf (mafbx) ubiquitin ligase
three-dimensional structure of p-glycoprotein
regulation of upstream binding factor 1 activity by insulin-like growth factor i receptor signaling
mechanisms of suppression of -synuclein neurotoxicity by geldanamycin in drosophila
actin activation of myosin heavy chain kinase a in dictyostelium
activation of cd38 by interleukin-8 signaling regulates intracellular ca2+ level and motility of lymphokine-activated killer cells
site-directed mutagenesis and kinetic studies of the west nile virus ns3 protease identify key enzyme-substrate interactions
association of nasp with hsp90 in mouse spermatogenic cells
iron-mediated h2o2 production as a mechanism for cell type-specific inhibition of tumor necrosis factor -induced but not interleukin-1-induced ib kinase complex/nuc..
insl5 is a high affinity specific agonist for gpcr142 (gpr100)
gene 33 is an endogenous inhibitor of epidermal growth factor (egf) receptor signaling and mediates dexamethasone-induced suppression of egf function
interaction of thiostrepton and elongation factor-g with the ribosomal protein l11-binding domain
strong and rapid induction of osteoblast differentiation by cbfa1/til-1 overexpression for bone regeneration
serum amyloid a is a ligand for scavenger receptor class b type i and inhibits high density lipoprotein binding and selective lipid uptake
allele-dependent similarity between viral and self-peptide presentation by hla-b27 subtypes
a major histocompatibility complex·peptide-restricted antibody and t cell receptor molecules recognize their target by distinct binding modes
roles of distal asp in heme oxygenase from corynebacterium diphtheriae, hmuo
the crystal structure of the herpes simplex virus 1 ssdna-binding protein suggests the structural basis for flexible, cooperative single-stranded dna binding
targeting of enteropathogenic escherichia coli espf to host mitochondria is essential for bacterial pathogenesis
characterization of the iron-sulfur cluster n7 (n1c) in the subunit nuog of the proton-translocating nadh-quinone oxidoreductase from escherichia coli
dominant-negative retinoic acid receptors elicit epidermal defects through a non-canonical pathway
crystal structure of a 92-residue c-terminal fragment of tonb from escherichia coli reveals significant conformational changes compared to structures of smaller ton..
antiviral activity of cyc202 in hiv-1-infected cells
recruitment of phosphoinositide 3-kinase defines a positive contribution of tyrosine kinase signaling to e-cadherin function
structures of dctp deaminase from escherichia coli with bound substrate and product
mechanical stretch stimulates protein kinase b/akt phosphorylation in epidermal cells via angiotensin ii type 1 receptor and epidermal growth factor receptor
structure and reactivity of human mitochondrial 2,4-dienoyl-coa reductase
identification of endoglin in rat hepatic stellate cells
functional and structural analysis of the gabaa receptor 1 subunit during channel gating and alcohol modulation
a crm1-dependent nuclear export pathway is involved in the regulation of irf-5 subcellular localization
identification of a novel partner of duox
parathyroid hormone uses multiple mechanisms to arrest the cell cycle progression of osteoblastic cells from g1 to s phase
stat-3-dependent cytosolic phospholipase a2 expression is required for thrombin-induced vascular smooth muscle cell motility
calpain and other cytosolic proteases can contribute to the degradation of retro-translocated prion protein in the cytosol
identification of the namh gene, encoding the hydroxylase responsible for the n-glycolylation of the mycobacterial peptidoglycan
identification of a prostaglandin-responsive element in the na,k-atpase 1 promoter that is regulated by camp and ca2+
activation of the epidermal growth factor receptor by respiratory syncytial virus results in increased inflammation and delayed apoptosis
characterization of structural changes in vimentin bearing an epidermolysis bullosa simplex-like mutation using site-directed spin labeling and electron paramagneti..
trpc1-mediated inhibition of 1-methyl-4-phenylpyridinium ion neurotoxicity in human sh-sy5y neuroblastoma cells
crystal structures of novel vascular endothelial growth factors (vegf) from snake venoms
mechanistic and structural analysis of a family 31 -glycosidase and its glycosyl-enzyme intermediate
genes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-her2 antibody through phosphatidylinositol 3-kinase-a..
in vivo and in vitro characterization of novel neuronal plasticity factors identified following spinal cord injury
structural changes of d1 c-terminal -carboxylate during s-state cycling in photosynthetic oxygen evolution
ser1928 is a common site for cav1.2 phosphorylation by protein kinase c isoforms
a na+/cl--coupled gaba transporter, gat-1, from caenorhabditis elegans
regulation of ultraviolet b-induced phosphorylation of histone h3 at serine 10 by fyn kinase
cis-acting element-specific transcriptional activity of differentially phosphorylated nuclear factor-b
the glutamine residue of the conserved ggq motif in saccharomyces cerevisiae release factor erf1 is methylated by the product of the ydr140w gene
rna interference analyses suggest a transcript-specific regulatory role for mitochondrial rna-binding proteins mrp1 and mrp2 in rna editing and other rna processing..
a novel stress-induced edem variant regulating endoplasmic reticulum-associated glycoprotein degradation
effects of unpaired nucleotides within hiv-1 genomic secondary structures on pausing and strand transfer
spermine causes loss of innate immune response to helicobacter pylori by inhibition of inducible nitric-oxide synthase translation
ve-cadherin links trna synthetase cytokine to anti-angiogenic function
variations on the gfp chromophore
ccmd is involved in complex formation between ccmc and the heme chaperone ccme during cytochrome c maturation
pro-angiogenic signaling by the endothelial presence of ceacam1
pivotal molecular determinants of peptidic and collagen triple helicase activities reside in the s3‘ subsite of matrix metalloproteinase 8 (mmp-8)
glycan-independent role of calnexin in the intracellular retention of charcot-marie-tooth 1a gas3/pmp22 mutants
glucocorticoids inhibit the transcriptional activity of lef/tcf in differentiating osteoblasts in a glycogen synthase kinase-3-dependent and -independent manner
three enzyme systems for galactoglycerolipid biosynthesis are coordinately regulated in plants
amyloid- protofibrils differ from amyloid- aggregates induced in dilute hexafluoroisopropanol in stability and morphology
in vitro characterization of a trna editing activity in the mitochondria of spizellomyces punctatus, a chytridiomycete fungus
prion-associated increases in src-family kinases
endothelin 1 induces 1pix translocation and cdc42 activation via protein kinase a-dependent pathway
identification of acnr, a tetr-type repressor of the aconitase gene acn in corynebacterium glutamicum
mutations of tubulin glycylation sites reveal cross-talk between the c termini of - and -tubulin and affect the ciliary matrix in tetrahymena
in vitro antibody evolution targeting germline hot spots to increase activity of an anti-cd22 immunotoxin
early painful diabetic neuropathy is associated with differential changes in the expression and function of vanilloid receptor 1
identification of human vps37c, a component of endosomal sorting complex required for transport-i important for viral budding
zinc transporters, znt5 and znt7, are required for the activation of alkaline phosphatases, zinc-requiring enzymes that are glycosylphosphatidylinositol-anchored to..
processive methylation of hemimethylated cpg sites by mouse dnmt1 dna methyltransferase
characterization of arabidopsis fluoroacetate-resistant mutants reveals the principal mechanism of acetate activation for entry into the glyoxylate cycle
amyloid fibril formation from sequences of a natural -structured fibrous protein, the adenovirus fiber
mutations in the spacer region of drosophila mitochondrial dna polymerase affect dna binding, processivity, and the balance between pol and exo function
sclerostin inhibition of wnt-3a-induced c3h10t1/2 cell differentiation is indirect and mediated by bone morphogenetic proteins
identification of the structural and functional domains of the large serine recombinase tnpx from clostridium perfringens
analysis of the localization and topology of nurim, a polytopic protein tightly associated with the inner nuclear membrane
the dileucine motif at the cooh terminus of human multidrug resistance p-glycoprotein is important for folding but not activity
rom2p, the rho1 gtp/gdp exchange factor of saccharomyces cerevisiae, can mediate stress responses via the ras-camp pathway
methylglyoxal, a metabolite derived from glycolysis, functions as a signal initiator of the high osmolarity glycerol-mitogen-activated protein kinase cascade and ca..
protein stoichiometry of a multiprotein complex, the human spliceosomal u1 small nuclear ribonucleoprotein
circulating fgf-23 is regulated by 1,25-dihydroxyvitamin d3 and phosphorus in vivo
differential regulation of chemokine expression by peroxisome proliferator-activated receptor agonists
heparin-binding epidermal growth factor-like growth factor links hepatocyte priming with cell cycle progression during liver regeneration
molecular dissection of interactions between components of the alternative pathway of complement and decay accelerating factor (cd55)
copper and zinc inhibit gs function
identification of ndhl and ssl1690 (ndho) in ndh-1l and ndh-1m complexes of synechocystis sp. pcc 6803
early growth response-1 regulates lipopolysaccharide-induced suppressor of cytokine signaling-1 transcription
selective inhibition of juxtanuclear translocation of protein kinase c ii by a negative feedback mechanism involving ceramide formed from the salvage pathway
differential stability of biogenesis intermediates reveals a common pathway for aquaporin-1 topological maturation
the rates of switching movement of troponin t between three states of skeletal muscle thin filaments determined by fluorescence resonance energy transfer
effect of amino acid substitutions in the rad50 atp binding domain on dna double strand break repair in yeast
the assembly of mreb, a prokaryotic homolog of actin
new genes implicated in the protection of anaerobically grown escherichia coli against nitric oxide
transforming growth factor- (tgf-) type i receptor/alk5-dependent activation of the gadd45 gene mediates the induction of biglycan expression by tgf-
involvement of chloride in apoptotic cell death induced by activation of atp-sensitive p2x7 purinoceptor
the unique c-terminal tail of the mitogen-activated protein kinase erk5 regulates its activation and nuclear shuttling
sphingolipid uptake by cultured cells
genetic evidence for a multi-subunit complex in coenzyme q biosynthesis in yeast and the role of the coq1 hexaprenyl diphosphate synthase
supramolecular amyloid-like assembly of the polypeptide sequence coded by exon 30 of human tropoelastin
characterization of peptides released from mitochondria
frat-2 preferentially increases glycogen synthase kinase 3-mediated phosphorylation of primed sites, which results in enhanced tau phosphorylation
endogenous protein kinase inhibitor terminates immediate-early gene expression induced by camp-dependent protein kinase (pka) signaling
utp induces osteopontin expression through a coordinate action of nfb, activator protein-1, and upstream stimulatory factor in arterial smooth muscle cells
kinetic analysis of the individual steps of protein splicing for the pyrococcus abyssi polii intein
promiscuity in the geometry of electrostatic interactions between the escherichia coli multidrug resistance transporter mdfa and cationic substrates
domains, amino acid residues, and new isoforms of caenorhabditis elegans diacylglycerol kinase 1 (dgk-1) important for terminating diacylglycerol signaling in vivo
insulin-like growth factor-1 (igf-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/akt/mammalian target of rapamycin (pi3k/akt/mto..
crystal structure of thrombin bound to heparin
enhanced dephosphorylation of camp-dependent protein kinase by oxidation and thiol modification
transcriptional regulation by lge1p requires a function independent of its role in histone h2b ubiquitination
double-stranded rnas from the helminth parasite schistosoma activate tlr3 in dendritic cells
cil-102 interacts with microtubule polymerization and causes mitotic arrest following apoptosis in the human prostate cancer pc-3 cell line
-conotoxin buia, a novel peptide from conus bullatus, distinguishes among neuronal nicotinic acetylcholine receptors
rgs14 is a centrosomal and nuclear cytoplasmic shuttling protein that traffics to promyelocytic leukemia nuclear bodies following heat shock
involvement of the c-src-crk-c3g-rap1 signaling in the nectin-induced activation of cdc42 and formation of adherens junctions
identification of a network involved in thapsigargin-induced apoptosis using a library of small interfering rna expression vectors
cardiotonic steroids differentially affect intracellular na+ and [na+]i/[k+]i-independent signaling in c7-mdck cells
specific inhibition and stabilization of aspergilloglutamic peptidase by the propeptide
cloning and functional analysis of the rhesus macaque abcg2 gene
evaluation of the 17-kda prenyl-binding protein as a regulatory protein for phototransduction in retinal photoreceptors
role of rho/rock and p38 map kinase pathways in transforming growth factor--mediated smad-dependent growth inhibition of human breast carcinoma cells in vivo
the ets domain transcription factor elk-1 regulates the expression of its partner protein, srf
tumor cell-mediated induction of the stromal factor stromelysin-3 requires heterotypic cell contact-dependent activation of specific protein kinase c isoforms
impact of the f508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure
rgs12 interacts with the snare-binding region of the cav2.2 calcium channel
molecular regulation of membrane resealing in 3t3 fibroblasts
myeloperoxidase potentiates nitric oxide-mediated nitrosation
bile acids induce a cationic current, depolarizing pancreatic acinar cells and increasing the intracellular na+ concentration
modeling of gs and gi regulation of human type v and vi adenylyl cyclase
a role for pet100p in the assembly of yeast cytochrome c oxidase
myocardial ischemia differentially regulates lkb1 and an alternate 5‘-amp-activated protein kinase kinase
translational control of 2-adrenergic receptor mrna by t-cell-restricted intracellular antigen-related protein
fyn phosphorylates human map-2c on tyrosine 67
human polyserase-2, a novel enzyme with three tandem serine protease domains in a single polypeptide chain
dna elongation by the human dna polymerase polymerase and terminal transferase activities are differentially coordinated by proliferating cell nuclear antigen and r..
evidence that the plastid translocon tic40 components possess modulating capabilities
macropinocytosis is the endocytic pathway that mediates macrophage foam cell formation with native low density lipoprotein
peroxiredoxin-linked detoxification of hydroperoxides in toxoplasma gondii
differential regulation of rad18 through rad6-dependent mono- and polyubiquitination
regulation of outside-in signaling in platelets by integrin-associated protein kinase c
depolarization activates erk and proline-rich tyrosine kinase 2 (pyk2) independently in different cellular compartments in hippocampal slices
involvement of nadp(h) in the interaction between heme oxygenase-1 and cytochrome p450 reductase
overexpression of mitogen-activated protein kinase kinase 6 in the heart improves functional recovery from ischemia in vitro and protects against myocardial infarct..
drosophila fear of intimacy encodes a zrt/irt-like protein (zip) family zinc transporter functionally related to mammalian zip proteins
the loss of glypican-3 induces alterations in wnt signaling
dynein light chain 1 phosphorylation controls macropinocytosis
conformational changes in bid, a pro-apoptotic bcl-2 family member, upon membrane binding
short term cyclin d1 overexpression induces centrosome amplification, mitotic spindle abnormalities, and aneuploidy
wnt-3a-dependent cell motility involves rhoa activation and is specifically regulated by dishevelled-2
transcript profiling in arabidopsis reveals complex responses to global inhibition of dna methylation and histone deacetylation
temporins, small antimicrobial peptides with leishmanicidal activity
interaction between transcription elongation factors and mrna 3‘-end formation at the saccharomyces cerevisiae gal10-gal7 locus
inhibition of integrin-mediated cell adhesion but not directional cell migration requires catalytic activity of ephb3 receptor tyrosine kinase
tandem promoters and developmentally regulated 5‘- and 3‘-mrna untranslated regions of the mouse scn5a cardiac sodium channel
phosphorylation of candida glabrata atp-binding cassette transporter cdr1p regulates drug efflux activity and atpase stability
the myotonic dystrophy type 1 triplet repeat sequence induces gross deletions and inversions
rac gtpase isoform-specific regulation of nadph oxidase and chemotaxis in murine neutrophils in vivo
thermodynamic and kinetic analysis of the nitrosyl, carbonyl, and dioxy heme complexes of neuronal nitric-oxide synthase
depletion of apolipoprotein n-acyltransferase causes mislocalization of outer membrane lipoproteins in escherichia coli
involvement of endoplasmic reticulum stress in insulin resistance and diabetes
nuclear translocation of caspase-3 is dependent on its proteolytic activation and recognition of a substrate-like protein(s)
dna methyltransferase gene ddnmt2 and longevity of drosophila
trypanosoma brucei glycoproteins contain novel giant poly-n-acetyllactosamine carbohydrate chains
endoplasmic reticulum stress stimulates heme oxygenase-1 gene expression in vascular smooth muscle
determinants of the t peptide involved in folding, degradation, and secretion of acetylcholinesterase
membrane-type matrix metalloproteinase-1 (mt1-mmp) is a processing enzyme for human laminin 2 chain
pea3 transcription factor cooperates with usf-1 in regulation of the murine bax transcription without binding to an ets-binding site
udp-glucuronic acid:anthocyanin glucuronosyltransferase from red daisy (bellis perennis) flowers
surfactant protein a binds mycoplasma pneumoniae with high affinity and attenuates its growth by recognition of disaturated phosphatidylglycerols
domain v of 2-glycoprotein i binds factor xi/xia and is cleaved at lys317-thr318
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