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免疫学杂志2005年第21期封面 购买


the devil in the details: the emerging role of anticitrulline autoimmunity in rheumatoid arthritis
cutting edge: cytotoxic granule polarization and cytolysis can occur without central supramolecular activation cluster formation in cd8 + effector t cells
cutting edge: trail deficiency accelerates hematological malignancies
cutting edge: cd4 + cd25 + regulatory t cells contribute to gender differences in susceptibility to experimental autoimmune encephalomyelitis
cutting edge: myd88 controls phagocyte nadph oxidase function and killing of gram-negative bacteria
cutting edge: cpg oligonucleotides induce splenic cd19 + dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent t cell regulatory functions via ifn..
cutting edge: a critical role for gene silencing in preventing excessive type 1 immunity
cutting edge: macrophage migration inhibitory factor is necessary for progression of experimental autoimmune encephalomyelitis
cutting edge: double-stranded dna breaks in the igv region gene were detected at lower frequency in affinity-maturation impeded ganp -/- mice
cutting edge: memory cd8 t cell maturation occurs independently of cd8
cutting edge: early ifn- signaling directly enhances primary antiviral cd4 + t cell responses
cd4-dependent signaling is required for a late checkpoint during th2 development associated with resistance to activation-induced cell death
cholera toxin b-subunit prevents activation and proliferation of human cd4 + t cells by activation of a neutral sphingomyelinase in lipid rafts
distinct effector mechanisms in the development of autoimmune neuropathy versus diabetes in nonobese diabetic mice
lyme arthritis synovial t cells instruct dendritic cells via fas ligand
tgf- 1 inhibits t-bet induction by ifn- in murine cd4 + t cells through the protein tyrosine phosphatase src homology region 2 domain-containing phosphatase-1
durable human memory t cells quantifiable by cultured enzyme-linked immunospot assays are induced by heterologous prime boost immunization and correlate with protec..
murine plasmacytoid dendritic cells produce ifn- upon il-4 stimulation
regulation of b7.1 costimulatory molecule is mediated by the ifn regulatory factor-7 through the activation of jnk in lipopolysaccharide-stimulated human monocytic ..
age-induced reprogramming of mast cell degranulation
induction of uteroglobin-related protein 2 ( ugrp2 ) gene expression by the th2 cytokines il-4 and il-13
estrogen receptor (er ) deficiency in macrophages results in increased stimulation of cd4 + t cells while 17 -estradiol acts through er to increase il-4 and gata-3 ..
tlr9- and fc ri-mediated responses oppose one another in plasmacytoid dendritic cells by down-regulating receptor expression
ex vivo rapamycin generates donor th2 cells that potently inhibit graft-versus-host disease and graft-versus-tumor effects via an il-4-dependent mechanism
physiological levels of 15-deoxy- 12,14 -prostaglandin j 2 prime eotaxin-induced chemotaxis on human eosinophils through peroxisome proliferator-activated receptor-..
molecular signature of recent thymic selection events on effector and regulatory cd4 + t lymphocytes
promiscuous thymic expression of an autoantigen gene does not result in negative selection of pathogenic t cells
human cd4 + t cells are predominantly distributed among six phenotypically and functionally distinct subsets
differential effects of b and t lymphocyte attenuator and programmed death-1 on acceptance of partially versus fully mhc-mismatched cardiac allografts
jnk1 is essential for cd8 + t cell-mediated tumor immune surveillance
nk cells infiltrating a mhc class i-deficient lung adenocarcinoma display impaired cytotoxic activity toward autologous tumor cells associated with altered nk cell-..
recognition of fresh human tumor by human peripheral blood lymphocytes transduced with a bicistronic retroviral vector encoding a murine anti-p53 tcr
inhibition of histone deacetylase suppresses osteoclastogenesis and bone destruction by inducing ifn- production
es-62, an immunomodulator secreted by filarial nematodes, suppresses clonal expansion and modifies effector function of heterologous antigen-specific t cells in vivo
cd4 t cell-independent antibody response promotes resolution of primary influenza infection and helps to prevent reinfection
selective modulation of cd4 + t cells from lupus patients by a promiscuous, protective peptide analog
the earliest thymic progenitors in adults are restricted to t, nk, and dendritic cell lineage and have a potential to form more diverse tcr chains than fetal progen..
a defect in deletion of nucleosome-specific autoimmune t cells in lupus-prone thymus: role of thymic dendritic cells
il-12 breaks dinitrothiocyanobenzene (dntb)-mediated tolerance and converts the tolerogen dntb into an immunogen
apoptosis of oligodendrocytes via fas and tnf-r1 is a key event in the induction of experimental autoimmune encephalomyelitis
il-12 and il-10 expression synergize to induce the immune-mediated eradication of established colon and mammary tumors and lung metastasis
molecular signatures distinguish human central memory from effector memory cd8 t cell subsets
respiratory syncytial virus infection of monocyte-derived dendritic cells decreases their capacity to activate cd4 t cells
ig gene rearrangement steps are initiated in early human precursor b cell subsets and correlate with specific transcription factor expression
tec kinases regulate tcr-mediated recruitment of signaling molecules and integrin-dependent cell adhesion
ifn- production by cd8 + t cells depends on nfat1 transcription factor and regulates th differentiation
differential processing of autoantigens in lysosomes from human monocyte-derived and peripheral blood dendritic cells
impact of peptides on the recognition of hla class i molecules by human hla antibodies
signaling through a mutant ifn- receptor
epigenetic control of highly homologous killer ig-like receptor gene alleles
the cyclic amp response element modulator regulates transcription of the tcr -chain
transcriptional activators of helper t cell fate are required for establishment but not maintenance of signature cytokine expression
the high frequency indian rhesus macaque mhc class i molecule, mamu-b01, does not appear to be involved in cd8 + t lymphocyte responses to siv mac 239
distinct regulation of h2-m3-restricted memory t cell responses in lymph node and spleen
osteopontin is not required for the development of th1 responses and viral immunity
tnf receptor-associated factor 6-dependent cd40 signaling primes macrophages to acquire antimicrobial activity in response to tnf-
differential tlr recognition of leptospiral lipid a and lipopolysaccharide in murine and human cells
dendritic cell maturation, but not cd8 + t cell induction, is dependent on type i ifn signaling during vaccination with adenovirus vectors
the myd88-dependent, but not the myd88-independent, pathway of tlr4 signaling is important in clearing nontypeable haemophilus influenzae from the mouse lung
nef is physically recruited into the immunological synapse and potentiates t cell activation early after tcr engagement
marco is the major binding receptor for unopsonized particles and bacteria on human alveolar macrophages
pattern recognition molecules activated by chlamydia muridarum infection of cloned murine oviduct epithelial cell lines
arginine-specific gingipains from porphyromonas gingivalis stimulate production of hepatocyte growth factor (scatter factor) through protease-activated receptors in..
lipopolysaccharide induces formyl peptide receptor 1 gene expression in macrophages and neutrophils via transcriptional and posttranscriptional mechanisms
differences in potency of cxc chemokine ligand 8-, cc chemokine ligand 11-, and c5a-induced modulation of integrin function on human eosinophils
il-4 inhibits the expression of mouse formyl peptide receptor 2, a receptor for amyloid 1-42, in tnf- -activated microglia 1,
the il-4 receptor -chain-binding cytokines, il-4 and il-13, induce forkhead box p3-expressing cd25 + cd4 + regulatory t cells from cd25 - cd4 + precursors
low-level cd4 + t cell activation is associated with low susceptibility to hiv-1 infection
selection of t cell clones expressing high-affinity public tcrs within human cytomegalovirus-specific cd8 t cell responses
cd8 bright cd56 + t cells are cytotoxic effectors in patients with active behçet?s uveitis
innate immunity and human b cell clonal expansion: effects on the recirculating b2 subpopulation
selective activation of peripheral blood t cell subsets by endotoxin infusion in healthy human subjects corresponds to differential chemokine activation
a role for b cell-activating factor of the tnf family in chemically induced autoimmunity
tumor progression can occur despite the induction of very high levels of self/tumor antigen-specific cd8 + t cells in patients with melanoma
il-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in scid mice through promoting cxcr-2-dependent angiogenesis
effects of mhc and gender on lupus-like autoimmunity in nba2 congenic mice
cd80/cd86 costimulation regulates acute vascular rejection
cdc2/cyclin b1 interacts with and modulates inositol 1,4,5-trisphosphate receptor (type 1) functions
protection against osteoporosis by active immunization with trance/rankl displayed on virus-like particles
increased susceptibility to complement attack due to down-regulation of decay-accelerating factor/cd55 in dysferlin-deficient muscular dystrophy 1,
a suppressive oligodeoxynucleotide enhances the efficacy of myelin cocktail/il-4-tolerizing dna vaccination and treats autoimmune disease
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