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免疫学杂志2004年第12期封面 购买


the fourth way? harnessing aggressive tendencies in the thymus
cutting edge: neutrophil granulocyte serves as a vector for leishmania entry into macrophages
cutting edge: tgf- signaling is required for the in vivo expansion and immunosuppressive capacity of regulatory cd4 + cd25 + t cells
cutting edge: tcr revision occurs in germinal centers
cutting edge: transpresentation of il-15 by bone marrow-derived cells necessitates expression of il-15 and il-15r by the same cells
cutting edge: a critical role for cd70 in cd8 t cell priming by cd40-licensed apcs
novel insights on human nk cells immunological modalities revealed by gene expression profiling
the solvent-inaccessible cys 67 residue of hla-b27 contributes to t cell recognition of hla-b27/peptide complexes
“pruning“ of alloreactive cd4 + t cells using 5- (and 6-)carboxyfluorescein diacetate succinimidyl ester prolongs skin allograft survival
pax5-deficient mice exhibit early onset osteopenia with increased osteoclast progenitors
plasmacytoid dendritic cell recruitment by immobilized cxcr3 ligands
early and quantal (by litter) expression of insulin autoantibodies in the nonobese diabetic mice predict early diabetes onset
the contraction phase of virus-specific cd8 + t cells is unaffected by a pan-caspase inhibitor
cellular flip (long isoform) overexpression in t cells drives th2 effector responses and promotes immunoregulation in experimental autoimmune encephalomyelitis
following immunization antigen becomes concentrated in a limited number of apcs including b cells
il-12 gene therapy is an effective therapeutic strategy for hepatocellular carcinoma in immunosuppressed mice
role of ctla-4 in the activation of single- and double-positive thymocytes
tolerance induction by veto ctls in the tcr transgenic 2c mouse model. i. relative reactivity of different veto cells
tolerance induction by veto ctls in the tcr transgenic 2c mouse model. ii. deletion of effector cells by fas-fas ligand apoptosis
ifn accelerates autoimmune type 1 diabetes in nonobese diabetic mice and breaks the tolerance to cells in nondiabetes-prone mice
follicular dendritic cells produce il-15 that enhances germinal center b cell proliferation in membrane-bound form
impact of ccr7 on priming and distribution of antiviral effector and memory ctl
shortening the infectious period does not alter expansion of cd8 t cells but diminishes their capacity to differentiate into memory cells
molecular characterization of a novel immune receptor restricted to the monocytic lineage
il-19 induced th2 cytokines and was up-regulated in asthma patients
phenotypic and functional characterization of cd4 t cells expressing killer ig-like receptors
individual nonobese diabetic mice exhibit unique patterns of cd8 + t cell reactivity to three islet antigens, including the newly identified widely expressed dystro..
mechanisms for macrophage-mediated hiv-1 induction
antiapoptotic microenvironment of acute myeloid leukemia
activation of dendritic cells that cross-present tumor-derived antigen licenses cd8 + ctl to cause tumor eradication
recruitment of uterine nk cells: induction of cxc chemokine ligands 10 and 11 in human endometrium by estradiol and progesterone
characterization of tumor reactivity of human v 9v 2 t cells in vitro and in scid mice in vivo
presence of diabetes-inhibiting, glutamic acid decarboxylase-specific, il-10-dependent, regulatory t cells in naive nonobese diabetic mice
molecular mechanisms of cd200 inhibition of mast cell activation
antibody repertoire development in fetal and neonatal pigs. vii. characterization of the preimmune light chain repertoire
biochemical analysis of the regulatory t cell protein lymphocyte activation gene-3 (lag-3; cd223)
transporter associated with antigen processing preselection of peptides binding to the mhc: a bioinformatic evaluation
ship2 is recruited to the cell membrane upon macrophage colony-stimulating factor (m-csf) stimulation and regulates m-csf-induced signaling
the glycosylation of human serum igd and ige and the accessibility of identified oligomannose structures for interaction with mannan-binding lectin
the membrane-proximal immunoreceptor tyrosine-based inhibitory motif is critical for the inhibitory signaling mediated by siglecs-7 and -9, cd33-related siglecs exp..
a novel adjuvant for mucosal immunity to hiv-1 gp120 in nonhuman primates
gene expression profiling of host response in models of acute hiv infection
ron receptor tyrosine kinase, a negative regulator of inflammation, inhibits hiv-1 transcription in monocytes/macrophages and is decreased in brain tissue from pati..
activation of virus-specific cd8 + t cells by lipopolysaccharide-induced il-12 and il-18
tlr-independent induction of dendritic cell maturation and adaptive immunity by negative-strand rna viruses
viral activation of macrophages through tlr-dependent and -independent pathways
interaction between complement regulators and streptococcus pyogenes : binding of c4b-binding protein and factor h/factor h-like protein 1 to m18 strains involves t..
human cd8 + t cells recognize the 60-kda cysteine-rich outer membrane protein from chlamydia trachomatis
nitric oxide inhibits ige-dependent cytokine production and fos and jun activation in mast cells
platelet-activating factor and kinin-dependent vascular leakage as a novel functional activity of the soluble terminal complement complex
a novel mechanism for tnf- regulation by p38 mapk: involvement of nf- b with implications for therapy in rheumatoid arthritis
ccr1 and cc chemokine ligand 5 interactions exacerbate innate immune responses during sepsis
interaction of soluble form of recombinant extracellular tlr4 domain with md-2 enables lipopolysaccharide binding and attenuates tlr4-mediated signaling
prostaglandin e 2 promotes the survival of bone marrow-derived dendritic cells
rhoa/rho-associated kinase pathway selectively regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via activation of i b ki..
lipopolysaccharide induces matrix metalloproteinase-9 expression via a mitochondrial reactive oxygen species-p38 kinase-activator protein-1 pathway in raw 264.7 cells
immunity to the extracellular domain of nogo-a modulates experimental autoimmune encephalomyelitis
involvement of eotaxin, eosinophils, and pancreatic predisposition in development of type 1 diabetes mellitus in the biobreeding rat
nf- b activation in airways modulates allergic inflammation but not hyperresponsiveness
inhibition of fractalkine ameliorates murine collagen-induced arthritis
cxc chemokine ligand 10 neutralization suppresses the occurrence of diabetes in nonobese diabetic mice through enhanced cell proliferation without affecting insulitis
combinations of anti-lfa-1, everolimus, anti-cd40 ligand, and allogeneic bone marrow induce central transplantation tolerance through hemopoietic chimerism, includi..
tracking of proinflammatory collagen-specific t cells in early and late collagen-induced arthritis in humanized mice
a novel hla-a3303-restricted minor histocompatibility antigen encoded by an unconventional open reading frame of human tmsb4y gene
anti-phospholipid antibodies restore mesenteric ischemia/reperfusion-induced injury in complement receptor 2/complement receptor 1-deficient mice
self-reactive t cell receptor-reactive cd8 + t cells inhibit t cell lymphoma growth in vivo
tlr4 contributes to disease-inducing mechanisms resulting in central nervous system autoimmune disease
intranasal hiv-1-gp160-dna/gp41 peptide prime-boost immunization regimen in mice results in long-term hiv-1 neutralizing humoral mucosal and systemic immunity
notch governing mature t cell differentiation
cutting edge: tlr4 activation mediates liver ischemia/reperfusion inflammatory response via ifn regulatory factor 3-dependent myd88-independent pathway
cutting edge: cd28-mediated transcriptional and posttranscriptional regulation of il-2 expression are controlled through different signaling pathways
cutting edge: persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy
cutting edge: expression patterns of surface and soluble triggering receptor expressed on myeloid cells-1 in human endotoxemia
cutting edge: cbl-b: one of the key molecules tuning cd28- and ctla-4-mediated t cell costimulation
analysis of the major patterns of b cell gene expression changes in response to short-term stimulation with 33 single ligands
cxcr4-tropic hiv-1 envelope glycoprotein functions as a viral chemokine in unstimulated primary cd4 + t lymphocytes
il-3 induces expression of lymphatic markers prox-1 and podoplanin in human endothelial cells
il-27 mediates complete regression of orthotopic primary and metastatic murine neuroblastoma tumors: role for cd8 + t cells
intestinal cryptopatch formation in mice requires lymphotoxin and the lymphotoxin receptor
intestinal t cells differentiate and rearrange antigen receptor genes in situ in the human infant
n -acetylglucosaminyltransferase v (mgat5)-mediated n -glycosylation negatively regulates th1 cytokine production by t cells
vaccine-stimulated, adoptively transferred cd8 + t cells traffic indiscriminately and ubiquitously while mediating specific tumor destruction
induction of central tolerance by mature t cells
coordinated expression of ig-like inhibitory mhc class i receptors and acquisition of cytotoxic function in human cd8 + t cells
neuromedin elicits cytokine release in murine th2-type t cell clone d10.g4.
ctla-4 engagement acts as a brake on cd4 + t cell proliferation and cytokine production but is not required for tuning t cell reactivity in adaptive tolerance
regulatory t cell suppression and anergy are differentially regulated by proinflammatory cytokines produced by tlr-activated dendritic cells
cd25 - t cells generate cd25 + foxp3 + regulatory t cells by peripheral expansion
endogenous ifn- production by plasmacytoid dendritic cells exerts an antiviral effect on thymic hiv-1 infection
papillon-lefèvre syndrome: correlating the molecular, cellular, and clinical consequences of cathepsin c/dipeptidyl peptidase i deficiency in humans
chemoattractant signals and 2 integrin occupancy at apical endothelial contacts combine with shear stress signals to promote transendothelial neutrophil migration
anatomical heterogeneity of memory cd4 + t cells due to reversible adaptation to the microenvironment
differential activation of erk, p38, and jnk required for th1 and th2 deviation in myelin-reactive t cells induced by altered peptide ligand
a sudden decline in active membrane-bound tgf- impairs both t regulatory cell function and protection against autoimmune diabetes
plasmablast and plasma cell production and distribution in trout immune tissues
expansion of myeloid suppressor cells in ship-deficient mice represses allogeneic t cell responses
early growth response gene-2, a zinc-finger transcription factor, is required for full induction of clonal anergy in cd4 + t cells
peptidoglycan molecular requirements allowing detection by the drosophila immune deficiency pathway
site-specific inhibitors of nadph oxidase activity and structural probes of flavocytochrome b : characterization of six monoclonal antibodies to the p22 phox subunit
plasticity within the antigen-combining site may manifest as molecular mimicry in the humoral immune response
genetic dissection of lupus pathogenesis: sle3/5 impacts igh cdr3 sequences, somatic mutations, and receptor editing
a distinct region of the murine ifn- promoter is hypomethylated from early t cell development through mature naive and th1 cell differentiation, but is hypermethyla..
chicken ig-like receptor b2, a member of a multigene family, is mainly expressed on b lymphocytes, recruits both src homology 2 domain containing protein tyrosine p..
key molecular contacts promote recognition of the baff receptor by tnf receptor-associated factor 3: implications for intracellular signaling regulation
tlr2 recognizes a bacterial lipopeptide through direct binding
tlrs govern neutrophil activity in aspergillosis
ifn regulatory factor 3-dependent induction of type i ifns by intracellular bacteria is mediated by a tlr- and nod2-independent mechanism
human monocytes infected with yersinia pestis express cell surface tlr9 and differentiate into dendritic cells
innate imprinting by the modified heat-labile toxin of escherichia coli (ltk63) provides generic protection against lung infectious disease
exploiting type 3 complement receptor for tnf- suppression, immune evasion, and progressive pulmonary fungal infection
helminth antigens modulate tlr-initiated dendritic cell activation
reconstitution of chemotactic peptide-induced nicotinamide adenine dinucleotide phosphate (reduced) oxidase activation in transgenic cos-phox cells
demonstration of the involvement of outer surface protein e coiled coil structural domains and higher order structural elements in the binding of infection-induced ..
herpesvirus-specific cd8 t cell immunity in old age: cytomegalovirus impairs the response to a coresident ebv infection
il-27 signaling compromises control of bacterial growth in mycobacteria-infected mice
hiv-1-induced migration of monocyte-derived dendritic cells is associated with differential activation of mapk pathways
the virulence function of streptococcus pneumoniae surface protein a involves inhibition of complement activation and impairment of complement receptor-mediated pro..
o -acetylation of cryptococcal capsular glucuronoxylomannan is essential for interference with neutrophil migration
in vivo and in vitro roles of il-21 in inflammation
nonredundant function of phosphodiesterases 4d and 4b in neutrophil recruitment to the site of inflammation
adenine nucleotides inhibit cytokine generation by human mast cells through a g s -coupled receptor
il-10 released by concomitant tlr2 stimulation blocks the induction of a subset of th1 cytokines that are specifically induced by tlr4 or tlr3 in human dendritic ce..
immunostimulatory dna reverses established allergen-induced airway remodeling
pulmonary chemokine expression is coordinately regulated by stat1, stat6, and ifn-
protective and pathological roles of virus-specific and bystander cd8 + t cells in herpetic stromal keratitis
fas death receptor signaling represses monocyte numbers and macrophage activation in vivo
role of cd44 and hyaluronan in neutrophil recruitment
induction of il-8 release in lung cells via activator protein-1 by recombinant baculovirus displaying severe acute respiratory syndrome-coronavirus spike proteins: ..
fas ligand is required for resolution of granulomatous experimental autoimmune thyroiditis
selective growth, in vitro and in vivo, of individual t cell clones from tumor-infiltrating lymphocytes obtained from patients with melanoma
autoimmunity to dna and nucleosomes in binary tetracycline-regulated polyomavirus t-ag transgenic mice
atorvastatin inhibits autoreactive b cell activation and delays lupus development in new zealand black/white f 1 mice
t cell activation by antibody-like immunoreceptors: increase in affinity of the single-chain fragment domain above threshold does not increase t cell activation aga..
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