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免疫学杂志2004年第11期封面 购买


mechanisms of soluble cytokine receptor generation
cutting edge: engagement of cd160 by its hla-c physiological ligand triggers a unique cytokine profile secretion in the cytotoxic peripheral blood nk cell subset
cutting edge: identification of hepatitis c virus-specific cd8 + t cells restricted by donor hla alleles following liver transplantation
regulation of b cell differentiation and plasma cell generation by il-21, a novel inducer of blimp-1 and bcl-6
vaccination in humans generates broad t cell cytokine responses
deranged early t cell development in immunodeficient strains of nonobese diabetic mice
cd28 and lipid rafts coordinate recruitment of lck to the immunological synapse of human t lymphocytes
-defensin-2 expression is regulated by tlr signaling in intestinal epithelial cells
rapid induction of splenic and peritoneal b-1a cells in adult mice by thymus-independent type-2 antigen
transgenic expression of ctla-4 controls lymphoproliferation in il-2-deficient mice
the selective increase in caspase-3 expression in effector but not memory t cells allows susceptibility to apoptosis
the regulated expression of a diverse set of genes during thymocyte positive selection in vivo
b7-h3 enhances tumor immunity in vivo by costimulating rapid clonal expansion of antigen-specific cd8 + cytolytic t cells
functionally impaired hiv-specific cd8 t cells show high affinity tcr-ligand interactions
prostaglandin e 2 -dependent enhancement of tissue inhibitors of metalloproteinases-1 production limits dendritic cell migration through extracellular matrix
target antigens determine graft-versus-host disease phenotype
evolution of transcriptional control of the igh locus: characterization, expression, and function of tf12/heb homologs of the catfish 1,
specificity-based negative selection of autoreactive b cells during memory formation
cd4 phosphorylation partially reverses nef down-regulation of cd4
altered th1 cell differentiation programming by ciita deficiency
viral macrophage-inflammatory protein-ii: a viral chemokine that differentially affects adaptive mucosal immunity compared with its mammalian counterparts
delineation of signals required for thymocyte positive selection
differential regulation of th1/th2 cytokine responses by placental protein 14
germline transcription and switch recombination of a transgene containing the entire h chain constant region locus: effect of a mutation in a stat6 binding site in ..
complement inactivation by recombinant human c3 derivatives
roles of tnf receptor-associated factor 3 in signaling to b lymphocytes by carboxyl-terminal activating regions 1 and 2 of the ebv-encoded oncoprotein latent membra..
b lymphocyte-induced maturation protein (blimp)-1, ifn regulatory factor (irf)-1, and irf-2 can bind to the same regulatory sites
the interaction between gata proteins and activator protein-1 promotes the transcription of il - 13 in mast cells
shark ig light chain junctions are as diverse as in heavy chains
nf- b regulates expression of the mhc class i-related chain a gene in activated t lymphocytes
exclusion and inclusion of tcr proteins during t cell development in tcr-transgenic and normal mice
the b lymphocyte adaptor molecule of 32 kilodaltons (bam32) regulates b cell antigen receptor internalization
conformational restraints and flexibility of 14-meric peptides in complex with hla-b3501
the actin cytoskeleton controls the efficiency of killer ig-like receptor accumulation at inhibitory nk cell immune synapses
the il-27 receptor (wsx-1) is an inhibitor of innate and adaptive elements of type 2 immunity
dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin mediates binding and internalization of aspergillus fumigatus conidia by dendritic ce..
cross-presentation of listeria -derived cd8 t cell epitopes requires unstable bacterial translation products
reduced apoptosis and ameliorated listeriosis in trail-null mice
pseudomonas aeruginosa flagellin and alginate elicit very distinct gene expression patterns in airway epithelial cells: implications for cystic fibrosis disease
human monoclonal antibodies to pseudomonas aeruginosa alginate that protect against infection by both mucoid and nonmucoid strains
duration of infection and antigen display have minimal influence on the kinetics of the cd4 + t cell response to listeria monocytogenes infection
expression of functional tlr4 confers proinflammatory responsiveness to trypanosoma cruzi glycoinositolphospholipids and higher resistance to infection with t. cruzi
rac1 contributes to maximal activation of stat1 and stat3 in ifn- -stimulated rat astrocytes
n-terminal residues of the chemotaxis inhibitory protein of staphylococcus aureus are essential for blocking formylated peptide receptor but not c5a receptor
polymorphonuclear cell transmigration induced by pseudomonas aeruginosa requires the eicosanoid hepoxilin a 3
a new pharmacological effect of salicylates: inhibition of nfat-dependent transcription
protein kinase c is required for p47 phox phosphorylation and translocation in activated human monocytes
urokinase induces basophil chemotaxis through a urokinase receptor epitope that is an endogenous ligand for formyl peptide receptor-like 1 and -like 2
toll receptor-mediated regulation of nadph oxidase in human dendritic cells
the inhibitory receptor pir-b negatively regulates neutrophil and macrophage integrin signaling
selective blockade of nf- b activity in airway immune cells inhibits the effector phase of experimental asthma
interference with heparin binding and oligomerization creates a novel anti-inflammatory strategy targeting the chemokine system
a role for nf- b subunits p50 and p65 in the inhibition of lipopolysaccharide-induced shock
green tea epigallocatechin-3-gallate mediates t cellular nf- b inhibition and exerts neuroprotection in autoimmune encephalomyelitis
crucial role of inhibitor of dna binding/differentiation in the vascular endothelial growth factor-induced activation and angiogenic processes of human endothelial ..
cc chemokine ligand 18, an atopic dermatitis-associated and dendritic cell-derived chemokine, is regulated by staphylococcal products and allergen exposure
targeting il-15 receptor-bearing cells with an antagonist mutant il-15/fc protein prevents disease development and progression in murine collagen-induced arthritis
mixed xenogeneic chimerism induces donor-specific humoral and cellular immune tolerance for cardiac xenografts
intravenous injection of a d1 protein of the smith proteins postpones murine lupus and induces type 1 regulatory t cells
long-term stable expanded human cd4 + t cell clones specific for human cytomegalovirus are distributed in both cd45ra high and cd45ro high populations
identification of a human hla-e-restricted cd8 + t cell subset in volunteers immunized with salmonella enterica serovar typhi strain ty21a typhoid vaccine
cellular immune responses to the hepatitis b virus polymerase 1,
hypoallergenic variants of the major latex allergen hev b 6.01 retaining human t lymphocyte reactivity
costimulation requirements of induced murine systemic autoimmune disease
tlr signaling: an emerging bridge from innate immunity to atherogenesis
cutting edge: human eosinophils regulate t cell subset selection through indoleamine 2,3-dioxygenase
cutting edge: bone morphogenetic protein antagonists drm/gremlin and dan interact with slits and act as negative regulators of monocyte chemotaxis 1,
cutting edge: immunity and ifn- production during listeria monocytogenes infection in the absence of t-bet
cutting edge: tumor-specific ctl are constitutively cross-armed in draining lymph nodes and transiently disseminate to mediate tumor regression following systemic c..
cutting edge: cross-presentation of cell-associated antigens to mhc class i molecule is regulated by a major transcription factor for heat shock proteins
replication-dependent potent ifn- induction in human plasmacytoid dendritic cells by a single-stranded rna virus
4-1bb and ox40 act independently to facilitate robust cd8 and cd4 recall responses
mechanism of prostaglandin (pg)e 2 -induced prolactin expression in human t cells: cooperation of two pge 2 receptor subtypes, e-prostanoid (ep) 3 and ep4, via calc..
eosinophil adhesion to cholinergic imr-32 cells protects against induced neuronal apoptosis
rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles
impaired receptor editing in the primary b cell repertoire of bash-deficient mice
extract of reishi polysaccharides induces cytokine expression via tlr4-modulated protein kinase signaling pathways
cd63 as an activation-linked t cell costimulatory element
the role of b cell-mediated t cell costimulation in the efficacy of the t cell retargeting bispecific antibody bis20x3
rescuing melanoma epitope-specific cytolytic t lymphocytes from activation-induced cell death, by sp600125, an inhibitor of jnk: implications in cancer immunotherapy
the immunization site of cytokine-secreting tumor cell vaccines influences the trafficking of tumor-specific t lymphocytes and antitumor efficacy against regional t..
final antigenic melan-a peptides produced directly by the proteasomes are preferentially selected for presentation by hla-a0201 in melanoma cells
evidence of a novel il-2/15r -targeted cytokine involved in homeostatic proliferation of memory cd8 + t cells
mechanisms of peritoneal b-1a cells accumulation induced by murine lupus susceptibility locus sle2
induction of bystander suppression by feeding antigen occurs despite normal clonal expansion of the bystander t cell population
homeostatic proliferation of a qa-1 b -restricted t cell: a distinction between the ligands required for positive selection and for proliferation in lymphopenic hosts
negative regulation of nk cell activities by inhibitory receptor cd94/nkg2a leads to altered nk cell-induced modulation of dendritic cell functions in chronic hepat..
vasoactive intestinal peptide modulates langerhans cell immune function
antigen targeting to cd11b allows efficient presentation of cd4 + and cd8 + t cell epitopes and in vivo th1-polarized t cell priming
augmentation of t cell levels and responses induced by androgen deprivation
a general survey of thymocyte differentiation by transcriptional analysis of knockout mouse models
regulated recruitment of mhc class ii and costimulatory molecules to lipid rafts in dendritic cells
expression and characterization of a novel cd6 ligand in cells derived from joint and epithelial tissues
human ribonuclease a superfamily members, eosinophil-derived neurotoxin and pancreatic ribonuclease, induce dendritic cell maturation and activation
vesicle size influences the trafficking, processing, and presentation of antigens in lipid vesicles
dietary docosahexaenoic acid suppresses t cell protein kinase c lipid raft recruitment and il-2 production
i b kinase complex kinase activity controls chemokine and high endothelial venule gene expression in lymph nodes and nasal-associated lymphoid tissue
follicular dendritic cell regulation of cxcr4-mediated germinal center cd4 t cell migration
b cells expressing bcl-2 and a signaling-impaired baff-specific receptor fail to mature and are deficient in the formation of lymphoid follicles and germinal centers
piasy-deficient mice display modest defects in ifn and wnt signaling
long distance control of mhc class ii expression by multiple distal enhancers regulated by regulatory factor x complex and ciita
differential gene expression modulated by the cytoplasmic domain of fc ria (cd64) -chain
the bax n terminus is required for negative regulation by the mitogen-activated protein kinase kinase and akt signaling pathways in t cells
hiv-1 tat-mediated effects on focal adhesion assembly and permeability in brain microvascular endothelial cells
identification and partial characterization of a variant of human cxcr3 generated by posttranscriptional exon skipping
enhancer role of stat5 in cd2 activation of ifn- gene expression
the 3‘ untranslated region of the membrane-bound il-1r accessory protein mrna confers tissue-specific destabilization
the functional interaction of the 2 integrin lymphocyte function-associated antigen-1 with junctional adhesion molecule-a is mediated by the i domain 1,
differential regulation of primary and secondary cd8 + t cells in the central nervous system
involvement of fc r i (cd64) in the mechanism of hiv-1 inhibition by polyclonal igg purified from infected patients in cultured monocyte-derived macrophages
single-epitope dna vaccination prevents exhaustion and facilitates a broad antiviral cd8 + t cell response during chronic viral infection
maximum immunobioactivity of murine small intestinal intraepithelial lymphocytes resides in a subpopulation of cd43 + t cells
genetic manipulation of telomerase in hiv-specific cd8 + t cells: enhanced antiviral functions accompany the increased proliferative potential and telomere length s..
cmv1 -independent antiviral role of nk cells revealed in murine cytomegalovirus-infected new zealand white mice
pathogen-induced apoptotic neutrophils express heat shock proteins and elicit activation of human macrophages
hematopoietic cells are required to initiate a chlamydia trachomatis -specific cd8 + t cell response
multiple roles of clan (caspase-associated recruitment domain, leucine-rich repeat, and naip ciia het-e, and tp1-containing protein) in the mammalian innate immune ..
helminth infection protects mice from anaphylaxis via il-10-producing b cells
single mucosal, but not parenteral, immunization with recombinant adenoviral-based vaccine provides potent protection from pulmonary tuberculosis
apolipoprotein e modulates clearance of apoptotic bodies in vitro and in vivo, resulting in a systemic proinflammatory state in apolipoprotein e-deficient mice
ethanol blocks leukocyte recruitment and endothelial cell activation in vivo and in vitro
intranasal exposure of mice to house dust mite elicits allergic airway inflammation via a gm-csf-mediated mechanism
a novel role of cysteinyl leukotrienes to promote dendritic cell activation in the antigen-induced immune responses in the lung
platelet endothelial cell adhesion molecule deficiency or blockade significantly reduces leukocyte emigration in a majority of mouse strains
il-5 and granulocyte-macrophage colony-stimulating factor activate stat3 and stat5 and promote pim-1 and cyclin d3 protein expression in human eosinophils
cd56 bright nk cells are enriched at inflammatory sites and can engage with monocytes in a reciprocal program of activation
the class a macrophage scavenger receptor attenuates cxc chemokine production and the early infiltration of neutrophils in sterile peritonitis
group ib secretory phospholipase a 2 stimulates cxc chemokine ligand 8 production via erk and nf- b in human neutrophils
differential regulation of th2 and th1 lung inflammatory responses by protein kinase c
identification of selective basophil chemoattractants in human nasal polyps as insulin-like growth factor-1 and insulin-like growth factor-2
polymorphisms in the fc ri promoter region affecting transcription activity: a possible promoter-dependent mechanism for association between fc ri and atopy
suppression of ongoing experimental autoimmune encephalomyelitis by neutralizing the function of the p28 subunit of il-27
immune responses of breast cancer patients to mutated epidermal growth factor receptor (egf-rviii, egf-r, and de2-7 egf-r)
decreased expression of the ets family transcription factor fli-1 markedly prolongs survival and significantly reduces renal disease in mrl/ lpr mice
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