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dysregulated fc ri signaling and altered fyn and ship activities in lyn-deficient mast cells
basal ig /ig signals trigger the coordinated initiation of pre-b cell antigen receptor-dependent processes
t cell immunity induced by live, necrotic, and apoptotic tumor cells
a tumor-associated glycoprotein that blocks mhc class ii-dependent antigen presentation by dendritic cells
specific engagement of tlr4 or tlr3 does not lead to ifn- -mediated innate signal amplification and stat1 phosphorylation in resident murine alveolar macrophages
oral tolerance to nickel requires cd4 + invariant nkt cells for the infectious spread of tolerance and the induction of specific regulatory t cells
requirements of nk cells and proinflammatory cytokines in t cell-dependent neonatal autoimmune ovarian disease triggered by immune complex
resistance to cd4 + cd25 + regulatory t cells and tgf- in cbl-b -/- mice
tnf activates syk protein tyrosine kinase leading to tnf-induced mapk activation, nf- b activation, and apoptosis
two human ulbp/raet1 molecules with transmembrane regions are ligands for nkg2d
dissection of the hla-dr4 peptide repertoire in endocrine epithelial cells: strong influence of invariant chain and hla-dm expression on the nature of ligands
analysis of transcription factor expression during discrete stages of postnatal thymocyte differentiation
stat1 regulates lipopolysaccharide- and tnf- -dependent expression of transporter associated with antigen processing 1 and low molecular mass polypeptide 2 genes in..
the e2f-1 transcription factor promotes caspase-8 and bid expression, and enhances fas signaling in t cells
a short consensus repeat-containing complement regulatory protein of lamprey that participates in cleavage of lamprey complement 3
unprecedented multiplicity of ig transmembrane and secretory mrna forms in the cartilaginous fish
lymphomagenesis, hydronephrosis, and autoantibodies result from dysregulation of il-9 and are differentially dependent on th2 cytokines
peptide variants of viral ctl epitopes mediate positive selection and emigration of ag-specific thymocytes in vivo
tyrosine kinase 2 interacts with and phosphorylates receptor for activated c kinase-1, a wd motif-containing protein
direct repression of prdm1 by bcl-6 inhibits plasmacytic differentiation
tlr4 is the signaling but not the lipopolysaccharide uptake receptor 1,
suppression of ongoing adjuvant-induced arthritis by neutralizing the function of the p28 subunit of il-2
tlr9 is localized in the endoplasmic reticulum prior to stimulation
role of ifn regulatory factor-1 and il-12 in immunological resistance to pathogenesis of n -methyl- n -nitrosourea-induced t lymphoma
engagement of the pathogen survival response used by group a streptococcus to avert destruction by innate host defense
secretion of intracellular il-1 receptor antagonist (type 1) is dependent on p2x 7 receptor activation
activation, differentiation, and migration of naive virus-specific cd8 + t cells during pulmonary influenza virus infection
microbial dna induces a host defense reaction of human respiratory epithelial cells
cd25 + cd4 + cells contribute to th2 polarization during helminth infection by suppressing th1 response development
cooperative prosurvival activity by erk and akt in human alveolar macrophages is dependent on high levels of acid ceramidase activity
cd154 signaling regulates the th1 response to herpes simplex virus-1 and inflammation in infected corneas
schistosoma mansoni worms induce anergy of t cells via selective up-regulation of programmed death ligand 1 on macrophages
human dendritic cells respond to helicobacter pylori, promoting nk cell and th1-effector responses in vitro
fluid shear regulates the kinetics and receptor specificity of staphylococcus aureus binding to activated platelets
type i ifn protects permissive macrophages from legionella pneumophila infection through an ifn- -independent pathway
inhibition of farnesyltransferase prevents collagen-induced arthritis by down-regulation of inflammatory gene expression through suppression of p21 ras -dependent n..
the lectin-like domain of complement receptor 3 protects endothelial barrier function from activated neutrophils
differential induction of il-1 and tnf by cd40 ligand or cellular contact with stimulated t cells depends on the maturation stage of human monocytes
induction and maintenance of airway responsiveness to allergen challenge are determined at the age of initial sensitization
pneumolysin-induced lung injury is independent of leukocyte trafficking into the alveolar space
tnf-induced 2 integrin activation involves src kinases and a redox-regulated activation of p38 mapk
e-prostanoid-3 receptors mediate the proinflammatory actions of prostaglandin e 2 in acute cutaneous inflammation
immunoregulatory role of nitric oxide in kilham rat virus-induced autoimmune diabetes in dr-bb rats
regulation of endotoxin-induced proinflammatory activation in human coronary artery cells: expression of functional membrane-bound cd14 by human coronary artery smo..
antineuroinflammatory effect of nf- b essential modifier-binding domain peptides in the adoptive transfer model of experimental allergic encephalomyelitis
regulatory role of c5a on macrophage migration inhibitory factor release from neutrophils
an il-12-independent role for cd40-cd154 in mediating effector responses: studies in cell-mediated glomerulonephritis and dermal delayed-type hypersensitivity
blockade of allergic airway inflammation following systemic treatment with a b7-dendritic cell (pd-l2) cross-linking human antibody
an advanced intercross line resolves eae18 into two narrow quantitative trait loci syntenic to multiple sclerosis candidate loci
activated ets2 is required for persistent inflammatory responses in the motheaten viable model
a 3 adenosine receptor signaling contributes to airway inflammation and mucus production in adenosine deaminase-deficient mice
mucosal t cells bearing tcr play a protective role in intestinal inflammation
blockade of late stages of autoimmune diabetes by inhibition of the receptor for advanced glycation end products
essential role of md-2 in tlr4-dependent signaling during helicobacter pylori -associated gastritis
production of profibrotic cytokines by invariant nkt cells characterizes cirrhosis progression in chronic viral hepatitis
the myelin-associated oligodendrocytic basic protein region mobp15-36 encompasses the immunodominant major encephalitogenic epitope(s) for sjl/j mice and predicted ..
crisscross ctl induction by syt-ssx junction peptide and its hla-a2402 anchor substitute
foxp3 expressing cd4 + cd25 high regulatory t cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating t cells
a novel therapy of murine collagen-induced arthritis with soluble t1/st2
peritoneal exudate cells treated with calcitonin gene-related peptide suppress murine experimental autoimmune uveoretinitis via il-10
il-15 and the initiation of cell contact-dependent synovial fibroblast-t lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate
chlamydia pneumoniae stimulates ifn- synthesis through myd88-dependent, tlr2- and tlr4-independent induction of il-18 release
b cell positive selection: road map to the primary repertoire?
inducing experimental arthritis and breaking self-tolerance to joint-specific antigens with trackable, ovalbumin-specific t cells
the diabetes susceptibility locus idd5.1 on mouse chromosome 1 regulates icos expression and modulates murine experimental autoimmune encephalomyelitis
fine mapping, gene content, comparative sequencing, and expression analyses support ctla4 and nramp1 as candidates for idd5.1 and idd5.2 in the nonobese diabetic mo..
nk cells stimulate proliferation of t and nk cells through 2b4/cd48 interactions
the regulatory c-terminal determinants within mycobacterial heat shock protein 65 are cryptic and cross-reactive with the dominant self homologs: implications for t..
distinct maturation of, but not migration between, human monocyte-derived dendritic cells upon ingestion of apoptotic cells of early or late phases
maintenance of peritoneal b-1a lymphocytes in the absence of the spleen
mouse complement receptor-related gene y/p65-neutralized tumor vaccine induces antitumor activity in vivo
cutting edge: physiologic attenuation of proinflammatory transcription by the g s protein-coupled a2a adenosine receptor in vivo
different costimulatory and growth factor requirements for cd4 + and cd8 + t cell-mediated rejection
antigen distribution drives programmed antitumor cd8 cell migration and determines its efficiency
liver sinusoidal endothelial cells are insufficient to activate t cells
cd4 + cd25 + regulatory t cell repertoire formation in response to varying expression of a neo-self-antigen
reduction in the developmental potential of intrathymic t cell progenitors with age
delayed and restricted expression limits putative instructional opportunities of v 1.1/v 2 tcr in / lineage choice in the thymus
light expression by mucosal t cells may regulate ifn- expression in the intestine
expansion and contraction of the nk cell compartment in response to murine cytomegalovirus infection
differential regulatory capacity of cd25 + t regulatory cells and preactivated cd25 + t regulatory cells on development, functional activation, and proliferation of..
alteration of cell surface sialylation regulates antigen-induced naive cd8 + t cell responses
fas-mediated apoptosome formation is dependent on reactive oxygen species derived from mitochondrial permeability transition in jurkat cells
deficiency of cd11b or cd11d results in reduced staphylococcal enterotoxin-induced t cell response and t cell phenotypic changes
high mobility group box protein 1: an endogenous signal for dendritic cell maturation and th1 polarization
ccr5 regulates high dose oral tolerance by modulating cc chemokine ligand 2 levels in the galt
epstein-barr virus promotes human monocyte survival and maturation through a paracrine induction of ifn-
differences in signaling molecule organization between naive and memory cd4 + t lymphocytes
monomeric igg in intravenous ig preparations is a functional antagonist of fc rii and fc riiib
sustained early growth response gene 3 expression inhibits the survival of cd4/cd8 double-positive thymocytes
structural and functional characterization of complement c4 and c1s-like molecules in teleost fish: insights into the evolution of classical and alternative pathways
lipopolysaccharide-induced macrophage inflammatory response is regulated by ship
human complement factor i does not require cofactors for cleavage of synthetic substrates
serine residues 286, 288, and 293 within the ciita: a mechanism for down-regulating ciita activity through phosphorylation
constitutive and ligand-induced tcr degradation
generation of peptide mimics of the epitope recognized by trastuzumab on the oncogenic protein her-2/neu
the structure of h-2k b and k bm8 complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs t cell repertoire selection and..
a hierarchy of nuclear localization signals governs the import of the regulatory factor x complex subunits and mhc class ii expression
opioid antagonist naltrexone disrupts feedback interaction between µ and opioid receptors in splenocytes to prevent alcohol inhibition of nk cell function
listeria monocytogenes as a vaccine vector: virulence attenuation or existing antivector immunity does not diminish therapeutic efficacy
identification of neutrophil granule protein cathepsin g as a novel chemotactic agonist for the g protein-coupled formyl peptide receptor 1,
the major surface protein of wolbachia endosymbionts in filarial nematodes elicits immune responses through tlr2 and tlr4
incomplete humoral immunity against hepatitis c virus is linked with distinct recognition of putative multiple receptors by e2 envelope glycoprotein
the rapidity with which virus-specific cd8 + t cells initiate ifn- synthesis increases markedly over the course of infection and correlates with immunodominance
intercellular adhesion molecule 1 deficiency leads to impaired recruitment of t lymphocytes and enhanced host susceptibility to infection with trypanosoma cruzi
dual roles of pspc, a surface protein of streptococcus pneumoniae, in binding human secretory iga and factor h
origin and fate of lymphocytic choriomeningitis virus-specific cd8 + t cells coexpressing the inhibitory nk cell receptor ly49g2
differential gene expression identifies novel markers of cd4 + and cd8 + t cell activation following stimulation by mycobacterium tuberculosis
dendritic cell trafficking and antigen presentation in the human immune response to mycobacterium tuberculosis
immature dendritic cells (dcs) use chemokines and intercellular adhesion molecule (icam)-1, but not dc-specific icam-3-grabbing nonintegrin, to stimulate cd4 + t ce..
the low molecular weight gtpase rhoa and atypical protein kinase c are required for tlr2-mediated gene transcription
activity of - and -defensins against primary isolates of hiv-1
high bactericidal efficiency of type iia phospholipase a 2 against bacillus anthracis and inhibition of its secretion by the lethal toxin
tlr3-, tlr7-, and tlr9-mediated production of proinflammatory cytokines and chemokines from murine connective tissue type skin-derived mast cells but not from bone ..
double mechanism for apical tryptophan depletion in polarized human bronchial epithelium
the hybrid cytomegalovirus enhancer/chicken -actin promoter along with woodchuck hepatitis virus posttranscriptional regulatory element enhances the protective effi..
prostaglandin e 2 inhibits alveolar macrophage phagocytosis through an e-prostanoid 2 receptor-mediated increase in intracellular cyclic amp 1,
phosphatidylserine receptor-mediated recognition of archaeosome adjuvant promotes endocytosis and mhc class i cross-presentation of the entrapped antigen by phagoso..
increase in hepatic nkt cells in leukocyte cell-derived chemotaxin 2-deficient mice contributes to severe concanavalin a-induced hepatitis
helicobacter pylori arginase inhibits t cell proliferation and reduces the expression of the tcr -chain (cd3 )
proinflammatory chemokines, such as c-c chemokine ligand 3, desensitize µ-opioid receptors on dorsal root ganglia neurons
a structurally available encephalitogenic epitope of myelin oligodendrocyte glycoprotein specifically induces a diversified pathogenic autoimmune response
identification of peptides that antagonize formyl peptide receptor-like 1-mediated signaling
a caspase-6 and anti-human epidermal growth factor receptor-2 (her2) antibody chimeric molecule suppresses the growth of her2-overexpressing tumors
regulation of cockroach antigen-induced allergic airway hyperreactivity by the cxcr3 ligand cxcl9
rac and protein kinase c- regulate erks and cytosolic phospholipase a 2 in fc ri signaling to cysteinyl leukotriene synthesis in mast cells
requirement for cd28 in the effector phase of allergic airway inflammation
abundant expression of granzyme a, but not perforin, in granules of cd8 + t cells in galt: implications for immune control of hiv-1 infection
comparative analysis of the cd19 + and cd138 + cell antibody repertoires in the cerebrospinal fluid of patients with multiple sclerosis
distinct activation signals determine whether il-21 induces b cell costimulation, growth arrest, or bim-dependent apoptosis
evidence that invasion-inhibitory antibodies specific for the 19-kda fragment of merozoite surface protein-1 (msp-1 19 ) can play a protective role against blood-st..
age-associated change in the frequency of memory cd4 + t cells impairs long term cd4 + t cell responses to influenza vaccine
t follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-th1/th2 effector cells that provide help for b cells
t cells enhance the expression of experimental autoimmune encephalomyelitis by promoting antigen presentation and il-12 production
understanding the pro- and anti-inflammatory properties of il-27
cutting edge: pulmonary immunopathology mediated by antigen-specific expression of tnf- by antiviral cd8 + t cells
cutting edge: selective requirement for the wiskott-aldrich syndrome protein in cytokine, but not chemokine, secretion by cd4 + t cells
cutting edge: induction of the antigen-processing enzyme ifn- -inducible lysosomal thiol reductase in melanoma cells is stat1-dependent but ciita-independent
cell proliferation and stat6 pathways are negatively regulated in t cells by stat1 and suppressors of cytokine signaling
c3a and c3b activation products of the third component of complement (c3) are critical for normal liver recovery after toxic injury
cholera toxin prevents th1-mediated autoimmune disease by inducing immune deviation
role of gut-associated lymphoreticular tissues in antigen-specific intestinal iga immunity
tec kinase migrates to the t cell-apc interface independently of its pleckstrin homology domain
k + channel expression during b cell differentiation: implications for immunomodulation and autoimmunity
expression of the b7.1 costimulatory molecule on pancreatic cells abrogates the requirement for cd4 t cells in the development of type 1 diabetes
the gene related to anergy in lymphocytes, an e3 ubiquitin ligase, is necessary for anergy induction in cd4 t cells
mechanism by which orally administered -1,3-glucans enhance the tumoricidal activity of antitumor monoclonal antibodies in murine tumor models
b cell-activating factor belonging to the tnf family (baff)-r is the principal baff receptor facilitating baff costimulation of circulating t and b cells
decreased e47 in senescent b cell precursors is stage specific and regulated posttranslationally by protein turnover
il-10 plays an important role in the homeostatic regulation of the autoreactive repertoire in naive mice
no intrinsic deficiencies in cd8 + t cell-mediated antitumor immunity with aging
differential roles for ccr5 expression on donor t cells during graft-versus-host disease based on pretransplant conditioning
fty720-enhanced t cell homing is dependent on ccr2, ccr5, ccr7, and cxcr4: evidence for distinct chemokine compartments
lymphotoxin and tnf produced by b cells are dispensable for maintenance of the follicle-associated epithelium but are required for development of lymphoid follicles..
antigen-specific lymphocyte sequestration in lymphoid organs: lack of essential roles for l and 4 integrin-dependent adhesion or g i protein-coupled receptor signal..
nitric oxide regulates immune cell bioenergetic: a mechanism to understand immunomodulatory functions of nitric oxide-releasing anti-inflammatory drugs
bcl6 acts as an amplifier for the generation and proliferative capacity of central memory cd8 + t cells
human b cells express functional trail/apo-2 ligand after cpg-containing oligodeoxynucleotide stimulation
il-21 enhances and sustains cd8 + t cell responses to achieve durable tumor immunity: comparative evaluation of il-2, il-15, and il-21
differential requirement for ifn- in ctl maturation in acute murine graft-versus-host disease
the third signal in t cell-mediated autoimmune disease?
rap1 signaling is required for suppression of ras-generated reactive oxygen species and protection against oxidative stress in t lymphocytes
adenosine acts through a 2 receptors to inhibit il-2-induced tyrosine phosphorylation of stat5 in t lymphocytes: role of cyclic adenosine 3‘,5‘-monophosphate and ..
shp-1 and shp-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human t cell stimulation, but only receptor ligation pr..
t cell biasing by activated dendritic cells
tgf- 1 disrupts endotoxin signaling in microglial cells through smad3 and mapk pathways 1,
fully functional memory cd8 t cells in the absence of cd4 t cells
nucleolin is a second component of the cd154 mrna stability complex that regulates mrna turnover in activated t cells
kinase suppressor of ras couples ras to the erk cascade during t cell development
fcr interactions do not play a major role in inhibition of experimental autoimmune encephalomyelitis by anti-cd154 monoclonal antibodies
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