advantages and disadvantages of cytidine deamination
cutting edge: il-2 is critically required for the in vitro activation of cd4 + cd25 + t cell suppressor function
cutting edge: ntb-a activates nk cells via homophilic interaction
cutting edge: hemokinin has substance p-like function and expression in inflammation
cutting edge: effector memory cd8 + t cells play a prominent role in recall responses to secondary viral infection in the lung
promotion of allograft survival by cd4 + cd25 + regulatory t cells: evidence for in vivo inhibition of effector cell proliferation
small interfering rnas mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3
essential role of bystander cytotoxic cd122 + cd8 + t cells for the antitumor immunity induced in the liver of mice by -galactosylceramide
a spontaneously arising pancreatic tumor does not promote the differentiation of naive cd8 + t lymphocytes into effector ctl
tolerance to dna in (nzb x nzw)f 1 mice that inherit an anti-dna v h as a conventional µ h chain transgene but not as a v h knock-in transgene
mechanisms of v 1 t cell activation by microbial components
the antigen-presenting activity of fresh, adult parenchymal microglia and perivascular cells from retina
differential requirements for endosomal reduction in the presentation of two h2-e d -restricted epitopes from influenza hemagglutinin
enhanced t cell proliferation in mice lacking the p85 subunit of phosphoinositide 3-kinase
requirement for donor and recipient cd40 expression in cardiac allograft rejection: induction of th1 responses and influence of donor-derived dendritic cells
the novel murine cd4 + cd8 + thymocyte cell line exhibits lineage commitment into both cd4 + and cd8 + t cells by altering the intensity and the duration of anti-cd..
a novel approach to specific allergy treatment: the recombinant fusion protein of a bacterial cell surface (s-layer) protein and the major birch pollen allergen bet..
messenger rna-electroporated dendritic cells presenting mage-a3 simultaneously in hla class i and class ii molecules
elimination of an immunodominant cd4 + t cell epitope in human ifn- does not result in an in vivo response directed at the subdominant epitope
duration of alloantigen presentation and avidity of t cell antigen recognition correlate with immunodominance of ctl response to minor histocompatibility antigens
extensive replicative capacity of human central memory t cells
fatal acute lymphoblastic leukemia in mice transgenic for b cell-restricted bcl-x l and c- myc
nucleosomes are exposed at the cell surface in apoptosis
apcs in the anterior uveal tract do not migrate to draining lymph nodes
recruitment of transferrin receptor to immunological synapse in response to tcr engagement
unusual chemokine receptor antagonism involving a mitogen-activated protein kinase pathway
expression of l-selectin, but not cd44, is required for early neutrophil extravasation in antigen-induced arthritis
a signal through ox40 (cd134) allows anergic, autoreactive t cells to acquire effector cell functions
methylation of stat6 modulates stat6 phosphorylation, nuclear translocation, and dna-binding activity
comparative genomic analysis of two avian (quail and chicken) mhc regions 1,
evidence that the long murine terminal deoxynucleotidyltransferase isoform plays no role in the control of v(d)j junctional diversity
differential requirement for adapter proteins src homology 2 domain-containing leukocyte phosphoprotein of 76 kda and adhesion- and degranulation-promoting adapter ..
early target genes of il-12 and stat4 signaling in th cells
random screening of proteins for hla-a0201-binding nine-amino acid peptides is not sufficient for identifying cd8 t cell epitopes recognized in the context of hla-a..
characterization of the human ig heavy chain antigen binding complementarity determining region 3 using a newly developed software algorithm, joinsolver
identification of protein-protein interfaces implicated in cd80-cd28 costimulatory signaling
linker for activation of b cells: a functional equivalent of a mutant linker for activation of t cells deficient in phospholipase c- 1 binding
toll-like receptor 9 signaling activates nf- b through ifn regulatory factor-8/ifn consensus sequence binding protein in dendritic cells
infection-induced expansion of a mhc class ib-dependent intestinal intraepithelial t cell subset 1,
oligosaccharide side chains on human secretory iga serve as receptors for ricin
tnf influences chemokine expression of macrophages in vitro and that of cd11b + cells in vivo during mycobacterium tuberculosis infection
bacterial ghosts are an efficient delivery system for dna vaccines
pulmonary surfactant protein a inhibits macrophage reactive oxygen intermediate production in response to stimuli by reducing nadph oxidase activity
the upper and lower respiratory tracts differ in their requirement of ifn- and il-4 in controlling respiratory mycoplasma infection and disease
massive number of antigen-specific cd4 t cells during vaccination with live attenuated salmonella causes interclonal competition
production of ifn- by cd4 t cells is essential for resolving ehrlichia infection
molecular determinants regulating the pairing of nkg2 molecules with cd94 for cell surface heterodimer expression
induction of in vivo functional d b -restricted cytolytic t cell activity against a putative phosphate transport receptor of mycobacterium tuberculosis
flagellin promotes myeloid differentiation factor 88-dependent development of th2-type response
altered ebv viral load setpoint after hiv seroconversion is in accordance with lack of predictive value of ebv load for the occurrence of aids-related non-hodgkin l..
healthy individuals that control a latent infection with mycobacterium tuberculosis express high levels of th1 cytokines and the il-4 antagonist il-4 2
murine cytomegalovirus interference with antigen presentation has little effect on the size or the effector memory phenotype of the cd8 t cell response
toxoplasma gondii triggers myeloid differentiation factor 88-dependent il-12 and chemokine ligand 2 (monocyte chemoattractant protein 1) responses using distinct pa..
c3a enhances nerve growth factor-induced nfat activation and chemokine production in a human mast cell line, hmc-1
suppressors of cytokine signaling regulate fc receptor signaling and cell activation during immune renal injury
toll-like receptor 4 signaling by intestinal microbes influences susceptibility to food allergy
volume-sensitive chloride channels do not mediate activation-induced chloride efflux in human neutrophils
chemotaxis inhibitory protein of staphylococcus aureus binds specifically to the c5a and formylated peptide receptor
tl1a synergizes with il-12 and il-18 to enhance ifn- production in human t cells and nk cells
role of calcium in pancreatic islet cell death by ifn- /tnf-
tgf- 1 represses activation and resultant death of microglia via inhibition of phosphatidylinositol 3-kinase activity
bid truncation, bid/bax targeting to the mitochondria, and caspase activation associated with neutrophil apoptosis are inhibited by granulocyte colony-stimulating f..
distinct transcriptional programs activated by interleukin-10 with or without lipopolysaccharide in dendritic cells: induction of the b cell-activating chemokine, c..
effects of tnf- and ifn- on nitric oxide-induced neurotoxicity in the mouse brain
anti-inflammatory effects of mitogen-activated protein kinase kinase inhibitor u0126 in an asthma mouse model
intracellular and cell surface localization of a complex between m 2 integrin and promatrix metalloproteinase-9 progelatinase in neutrophils
iron chelator triggers inflammatory signals in human intestinal epithelial cells: involvement of p38 and extracellular signal-regulated kinase signaling pathways
humanin, a newly identified neuroprotective factor, uses the g protein-coupled formylpeptide receptor-like-1 as a functional receptor
type i collagen is the autoantigen in experimental autoimmune anterior uveitis
platelet-activating factor receptor develops airway hyperresponsiveness independently of airway inflammation in a murine asthma model
genomic and proteomic determinants of outcome in patients undergoing thoracoabdominal aortic aneurysm repair
cd56 + cells induce steroid resistance in b cells exposed to il-15
bcl-6 mutations in pulmonary lymphoproliferative disorders: demonstration of an aberrant immunological reaction in hiv-related lymphoid interstitial pneumonia
phosphatidylinositol 3-kinase is involved in 2(i) collagen gene expression in normal and scleroderma fibroblasts
stroma cell-derived factor 1 mediates desensitization of human neutrophil respiratory burst in synovial fluid from rheumatoid arthritic patients
type 2 monocyte and microglia differentiation mediated by glatiramer acetate therapy in patients with multiple sclerosis
topical glucocorticoid therapy directly induces up-regulation of functional cxcr4 on primed t lymphocytes in the aqueous humor of patients with uveitis
induction of human dendritic cell maturation using transfection with rna encoding a dominant positive toll-like receptor 4
t cell ig- and mucin-domain-containing molecule-3 (tim-3) and tim-1 molecules are differentially expressed on human th1 and th2 cells and in cerebrospinal fluid-der..
inhibition of b cell death causes the development of an iga nephropathy in (new zealand white x c57bl/6)f 1 - bcl-2 transgenic mice
a promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing fc riib alters receptor expression and associates with autoimmunity. i. regulator..
a promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing fc riib alters receptor expression and associates with autoimmunity. ii. differen..
adenovirus cd40 ligand gene therapy counteracts immune escape mechanisms in the tumor microenvironment
identification of an ssx-2 epitope presented by dendritic cells to circulating autologous cd4 + t cells
antiretroviral drug resistance mutations sustain or enhance ctl recognition of common hiv-1 pol epitopes
influence of coinfecting pathogens on hiv expression: evidence for a role of toll-like receptors
cutting edge: nk cells mediate igg1-dependent hyperacute rejection of xenografts
rapid development of t cell memory
expression characteristics and stimulatory functions of cd43 in human cd4 + memory t cells: analysis using a monoclonal antibody to cd43 that has a novel lineage sp..
dexamethasone suppresses antigen-induced activation of phosphatidylinositol 3-kinase and downstream responses in mast cells
the role of mrna turnover in the regulation of tristetraprolin expression: evidence for an extracellular signal-regulated kinase-specific, au-rich element-dependent..
il-1 suppresses prolonged akt activation and expression of e2f-1 and cyclin a in breast cancer cells
murine cd8 + recent thymic emigrants are e integrin-positive and cc chemokine ligand 25 responsive
c-maf and junb mediation of th2 differentiation induced by the type 2 g protein-coupled receptor (vpac 2 ) for vasoactive intestinal peptide
expression of human cd1d molecules protects target cells from nk cell-mediated cytolysis
costimulation via glucocorticoid-induced tnf receptor in both conventional and cd25 + regulatory cd4 + t cells
initial antigen encounter programs cd8 + t cells competent to develop into memory cells that are activated in an antigen-free, il-7- and il-15-rich environment
a novel role for p21-activated protein kinase 2 in t cell activation
elevated tgf- 1 secretion and down-modulation of nkg2d underlies impaired nk cytotoxicity in cancer patients
tumor-derived muc1 mucins interact with differentiating monocytes and induce il-10 high il-12 low regulatory dendritic cell
cd4 - cd8 subset of cd1d-restricted nkt cells controls t cell expansion
on the relevance of tcr rearrangement circles as molecular markers for thymic output during experimental graft-versus-host disease
il-12 pretreatments enhance ifn- -induced janus kinase-stat signaling and potentiate the antitumor effects of ifn- in a murine model of malignant melanoma
simvastatin augments lipopolysaccharide-induced proinflammatory responses in macrophages by differential regulation of the c-fos and c-jun transcription factors
kir2dl5 can inhibit human nk cell activation via recruitment of src homology region 2-containing protein tyrosine phosphatase-2 (shp-2)
host dendritic cells alone are sufficient to initiate acute graft-versus-host disease
activation of naive cd4 + t cells in vivo by a self-peptide mimic: mechanism of tolerance maintenance and preservation of immunity
increased and long-term generation of dendritic cells with reduced function from il-6-deficient bone marrow
chemokine monokine induced by ifn- /cxc chemokine ligand 9 stimulates t lymphocyte proliferation and effector cytokine production
peptides identified through phage display direct immunogenic antigen to dendritic cells
cd27 is acquired by primed b cells at the centroblast stage and promotes germinal center formation
ctla-4 regulates expansion and differentiation of th1 cells following induction of peripheral t cell tolerance
a two-step model of acute cd4 t-cell mediated cardiac allograft rejection
lymphotoxin- receptor activation by activated t cells induces cytokine release from mouse bone marrow-derived mast cells
distinct footprints of tcr engagement with highly homologous ligands
mhc-restricted ig v region-driven t-b lymphocyte collaboration: b cell receptor ligation facilitates switch to igg production
rat plasmacytoid dendritic cells are an abundant subset of mhc class ii + cd4 + cd11b - ox62 - and type i ifn-producing cells that exhibit selective expression of t..
coupling in silico and in vitro analysis of peptide-mhc binding: a bioinformatic approach enabling prediction of superbinding peptides and anchorless epitopes
the cd40-induced signaling pathway in endothelial cells resulting in the overexpression of vascular endothelial growth factor involves ras and phosphatidylinositol ..
characterization of a peptide inhibitor of janus kinase 2 that mimics suppressor of cytokine signaling 1 function
transcriptional regulation of human cd5: important role of ets transcription factors in cd5 expression in t cells
repression of ifn- expression by peroxisome proliferator-activated receptor
the electrostatic nature of c3d-complement receptor 2 association
bap29/31 influences the intracellular traffic of mhc class i molecules
binding of cytoplasmic proteins to the cd19 intracellular domain is high affinity, competitive, and multimeric
enhancer-mediated control of macrophage-specific arginase i expression
protection against progressive leishmaniasis by ifn-
akt decreases lymphocyte apoptosis and improves survival in sepsis
pulmonary collectins enhance phagocytosis of mycobacterium avium through increased activity of mannose receptor
il-10 is an important mediator of the enhanced susceptibility to pneumococcal pneumonia after influenza infection
neuroregulatory events follow adaptive immune-mediated elimination of hiv-1-infected macrophages: studies in a murine model of viral encephalitis
differential immune responses and protective efficacy induced by components of a tuberculosis polyprotein vaccine, mtb72f, delivered as naked dna or recombinant pro..
accumulation of t cells in the lungs and their regulatory roles in th1 response and host defense against pulmonary infection with cryptococcus neoformans
wsx-1: a key role in induction of chronic intestinal nematode infection
rac1 and toll-il-1 receptor domain-containing adapter protein mediate toll-like receptor 4 induction of hiv-long terminal repeat
ccr2-dependent trafficking of f4/80 dim macrophages and cd11c dim/intermediate dendritic cells is crucial for t cell recruitment to lungs infected with mycobacteriu..
differential regulation of tnf-r1 signaling: lipid raft dependency of p42 mapk/erk2 activation, but not nf- b activation
nk cells and polymorphonuclear neutrophils are both critical for il-2-induced pulmonary vascular leak syndrome
an annexin 1 n-terminal peptide activates leukocytes by triggering different members of the formyl peptide receptor family
15-deoxy- 12,14 -prostaglandin j 2 inhibits glucocorticoid binding and signaling in macrophages through a peroxisome proliferator-activated receptor -independent pr..
the transcriptional activation program of human neutrophils in skin lesions supports their important role in wound healing
staging the initiation of autoantibody-induced arthritis: a critical role for immune complexes
stat3 activation in acute lung injury
il-1 impairs insulin-like growth factor i-induced differentiation and downstream activation signals of the insulin-like growth factor i receptor in myoblasts
il-16 is constitutively present in peripheral blood monocytes and spontaneously released during apoptosis
adenosine-activated mast cells induce ige synthesis by b lymphocytes: an a 2b -mediated process involving th2 cytokines il-4 and il-13 with implications for asthma 1,
basophils infiltrate human gastric mucosa at sites of helicobacter pylori infection, and exhibit chemotaxis in response to h. pylori- derived peptide hp(2-20)
cd200 is a ligand for all members of the cd200r family of immunoregulatory molecules
labile zinc and zinc transporter znt 4 in mast cell granules: role in regulation of caspase activation and nf- b translocation
activation of phosphoinositide 3-kinases by the ccr4 ligand macrophage-derived chemokine is a dispensable signal for t lymphocyte chemotaxis
an in vitro model for the lepromatous leprosy granuloma: fate of mycobacterium leprae from target macrophages after interaction with normal and activated effector m..
shear-dependent capping of l-selectin and p-selectin glycoprotein ligand 1 by e-selectin signals activation of high-avidity 2 -integrin on neutrophils
membrane-bound matrix metalloproteinase-8 on activated polymorphonuclear cells is a potent, tissue inhibitor of metalloproteinase-resistant collagenase and serpinase
down-regulation of il-2 production in t lymphocytes by phosphorylated protein kinase a-rii
the allograft defines the type of rejection (acute versus chronic) in the face of an established effector immune response
alterations in lipid raft composition and dynamics contribute to abnormal t cell responses in systemic lupus erythematosus 1,
defective dendritic cell function in hiv-infected patients receiving effective highly active antiretroviral therapy: neutralization of il-10 production and depletio..
altered p38 mitogen-activated protein kinase expression in different leukocytes with increment of immunosuppressive mediators in patients with severe acute respirat..
development of antigen-specific cd8 + ctl in mhc class i-deficient mice through cd4 to cd8 conversion