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liver dendritic cells are less immunogenic than spleen dendritic cells because of differences in subtype composition
in a transgenic model of spontaneous autoimmune diabetes, expression of a protective class ii mhc molecule results in thymic deletion of diabetogenic cd8 + t cells
development of the dendritic cell system during mouse ontogeny
il-10 induces regulatory t cell apoptosis by up-regulation of the membrane form of tnf-
ultraviolet radiation-induced regulatory t cells not only inhibit the induction but can suppress the effector phase of contact hypersensitivity
activation of resting human primary t cells with chimeric receptors: costimulation from cd28, inducible costimulator, cd134, and cd137 in series with signals from t..
allelic variation at the v h a locus in natural populations of rabbit ( oryctolagus cuniculus, l.)
nf- b and oct-2 synergize to activate the human 3‘ igh hs4 enhancer in b cells
cd23 trimers are preassociated on the cell surface even in the absence of its ligand, ige
genomic ly49a transgenes: basis of variegated ly49a gene expression and identification of a critical regulatory element
quantitative analysis of prion-protein degradation by constitutive and immuno-20s proteasomes indicates differences correlated with disease susceptibility
polymorphisms in il-4r correlate with airways hyperreactivity, eosinophilia, and ym protein expression in allergic il-13 -/- mice
wnt target genes identified by dna microarrays in immature cd34 + thymocytes regulate proliferation and cell adhesion
enhanced catalytic action of hla-dm on the exchange of peptides lacking backbone hydrogen bonds between their n-terminal region and the mhc class ii -chain
role of commensal bacteria in development of gut-associated lymphoid tissues and preimmune antibody repertoire
the epidermal growth factor-seven transmembrane (egf-tm7) receptor cd97 is required for neutrophil migration and host defense
t cytotoxic-1 cd8 + t cells are effector cells against pneumocystis in mice
ige enhances parasite clearance and regulates mast cell responses in mice infected with trichinella spiralis
up-regulation of hlx in immature th cells induces ifn- expression
the cationic antimicrobial peptide ll-37 modulates dendritic cell differentiation and dendritic cell-induced t cell polarization
the role of signr1 and the -glucan receptor (dectin-1) in the nonopsonic recognition of yeast by specific macrophages
mice deficient in lrg-47 display increased susceptibility to mycobacterial infection associated with the induction of lymphopenia
staphylococcus aureus resists human defensins by production of staphylokinase, a novel bacterial evasion mechanism
expression of signaling lymphocytic activation molecule- associated protein interrupts ifn- production in human tuberculosis
the dendritic cell receptor dc-sign discriminates among species and life cycle forms of leishmania
generation of a complement-independent bactericidal igm against a relapsing fever borrelia
l-ficolin specifically binds to lipoteichoic acid, a cell wall constituent of gram-positive bacteria, and activates the lectin pathway of complement
identification of a novel fc riiia -associated molecule that contains significant homology to porcine cathelin
different functional capacities of latent and lytic antigen-specific cd8 t cells in murine gammaherpesvirus infection
carbon monoxide inhibits t lymphocyte proliferation via caspase-dependent pathway
prostaglandin e 2 induces degranulation-independent production of vascular endothelial growth factor by human mast cells
nk cell trail eliminates immature dendritic cells in vivo and limits dendritic cell vaccination efficacy
cxcr2 -/- mice show enhanced susceptibility to herpetic stromal keratitis: a role for il-6-induced neovascularization
semaphorin cd100 from activated t lymphocytes induces process extension collapse in oligodendrocytes and death of immature neural cells
chemokine secretion of rheumatoid arthritis synovial fibroblasts stimulated by toll-like receptor 2 ligands
bone marrow-derived progenitor cells are important for lung repair after lipopolysaccharide-induced lung injury
potential targets of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor for multiple sclerosis therapy
defective control of latent epstein-barr virus infection in systemic lupus erythematosus
periportal fibrosis in human schistosoma mansoni infection is associated with low il-10, low ifn-, high tnf-, or low rantes, depending on age and gender
nk cells regulate cd8 + t cell effector function in response to an intracellular pathogen
functional analysis of tumor-specific th cell responses detected in melanoma patients after dendritic cell-based immunotherapy
apc-independent activation of nk cells by the toll-like receptor 3 agonist double-stranded rna
analysis of gene expression and ig transcription in pu.1/spi-b-deficient progenitor b cell lines
cutting edge: il-7-dependent homeostatic proliferation of cd8 + t cells in neonatal mice allows the generation of long-lived natural memory t cells
fully functional hla b27-restricted cd4 + as well as cd8 + t cell responses in tcr transgenic mice
melanoma-reactive class i-restricted cytotoxic t cell clones are stimulated by dendritic cells loaded with synthetic peptides, but fail to respond to dendritic cell..
a repressor of gata-mediated negative feedback mechanism of t cell activation
tolerogenic apc generate cd8 + t regulatory cells that modulate pulmonary interstitial fibrosis
cd1-dependent regulation of chronic central nervous system inflammation in experimental autoimmune encephalomyelitis
cognate b cell signaling via mhc class ii: differential regulation of b cell antigen receptor and mhc class ii/ig- signaling by cd22
cutting edge: an endogenous pathway to systemic inflammatory response syndrome (sirs)-like reactions through toll-like receptor 4
inducible heat shock protein 70 promotes myelin autoantigen presentation by the hla class ii
regulation of cd103 expression by cd8 + t cells responding to renal allografts
superantigen stimulation reveals the contribution of lck to negative regulation of t cell activation
role of tnf receptor-associated factor 3 in the cd40 signaling by production of reactive oxygen species through association with p40 phox, a cytosolic subunit of ni..
effects of t cell frequency and graft size on transplant outcome in mice
t cell clonal conditioning: a phase occurring early after antigen presentation but before clonal expansion is impacted by toll-like receptor stimulation
expression of preproinsulin-2 gene shapes the immune response to preproinsulin in normal mice
human intestinal fibroblasts prevent apoptosis in human intestinal mast cells by a mechanism independent of stem cell factor, il-3, il-4, and nerve growth factor 1,
cxcr1 + cd4 + t cells in human allergic disease
colorectal cancer cells induce lymphocyte apoptosis by an endothelial monocyte-activating polypeptide-ii-dependent mechanism
the 1 1 and e 7 integrins define a subset of dendritic cells in peripheral lymph nodes with unique adhesive and antigen uptake properties
dendritic cell maturation controls adhesion, synapse formation, and the duration of the interactions with naive t lymphocytes
dermal enhancement: bacterial products on intact skin induce and augment organ-specific autoimmune disease
pulmonary tumors inefficiently prime tumor-specific t cells
dexamethasone inhibits il-12p40 production in lipopolysaccharide-stimulated human monocytic cells by down-regulating the activity of c-jun n-terminal kinase, the ac..
two distinct waves of membrane-proximal b cell antigen receptor signaling differentially regulated by src homology 2-containing inositol polyphosphate 5-phosphatase
b7 expression on t cells down-regulates immune responses through ctla-4 ligation via r-t interactions
partitioning of rearranged ig genes by mutation analysis demonstrates d-d fusion and v gene replacement in the expressed human repertoire
a functional c5a anaphylatoxin receptor in a teleost species
domain shuffling has been the main mechanism forming new hominoid killer cell ig-like receptors
the tetraspanin cd81 is necessary for partitioning of coligated cd19/cd21-b cell antigen receptor complexes into signaling-active lipid rafts
molecular characterization of a putative antiretroviral transcriptional factor, otk18
herpes simplex virus-specific cd8 + t cells can clear established lytic infections from skin and nerves and can partially limit the early spread of virus after cuta..
essential contribution of monocyte chemoattractant protein-1/c-c chemokine ligand-2 to resolution and repair processes in acute bacterial pneumonia
a role for tcr affinity in regulating naive t cell homeostasis
actinobacillus actinomycetemcomitans cytolethal distending toxin (cdt): evidence that the holotoxin is composed of three subunits: cdta, cdtb, and cdtc
localization of cystic fibrosis transmembrane conductance regulator to lipid rafts of epithelial cells is required for pseudomonas aeruginosa -induced cellular acti..
organism-specific neutrophil-endothelial cell interactions in response to escherichia coli, streptococcus pneumoniae, and staphylococcus aureus
critical role of t cell-dependent serum antibody, but not the gut-associated lymphoid tissue, for surviving acute mucosal infection with citrobacter rodentium, an a..
redox-sensing release of human thioredoxin from t lymphocytes with negative feedback loops
modulation of the phosphoinositide 3-kinase pathway alters innate resistance to polymicrobial sepsis
essential role for neutrophil recruitment to the liver in concanavalin a-induced hepatitis
stat1 plays a critical role in the regulation of antimicrobial effector mechanisms, but not in the development of th1-type responses during toxoplasmosis
hyperactivation of stat3 is involved in abnormal differentiation of dendritic cells in cancer
dendritic cells from malaria-infected mice are fully functional apc
conserved hierarchy of helper t cell responses in a chimpanzee during primary and secondary hepatitis c virus infections
galectin-3 mediates il-4-induced survival and differentiation of b cells: functional cross-talk and implications during trypanosoma cruzi infection
improved effector activity and memory cd8 t cell development by il-2 expression during experimental respiratory syncytial virus infection
neutrophil serine proteinases cleave bacterial flagellin, abrogating its host response-inducing activity
murine -herpesvirus-68-induced il-12 contributes to the control of latent viral burden, but also contributes to viral-mediated leukocytosis
il-23 induces stronger sustained ctl and th1 immune responses than il-12 in hepatitis c virus envelope protein 2 dna immunization
differential regulation of igg anti-capsular polysaccharide and antiprotein responses to intact streptococcus pneumoniae in the presence of cognate cd4 + t cell help
sensing environmental lipids by dendritic cell modulates its function
proteolytic regulation of the urokinase receptor/cd87 on monocytic cells by neutrophil elastase and cathepsin g
ifn-inducible protein 10/cxc chemokine ligand 10-independent induction of experimental autoimmune encephalomyelitis
intracellular regulation of fas-induced apoptosis in human fibroblasts by extracellular factors and cycloheximide
signal transducer and activator of transcription 3 is the dominant mediator of the anti-inflammatory effects of il-10 in human macrophages
membrane-associated il-1 contributes to chronic synovitis and cartilage destruction in human il-1 transgenic mice
soluble fractalkine prevents monocyte chemoattractant protein-1-induced monocyte migration via inhibition of stress-activated protein kinase 2/p38 and matrix metall..
neutralizing endogenous il-6 renders mast cells of the mc t type from lung, but not the mc tc type from skin and lung, susceptible to human recombinant il-4-induced..
cytoskeletal reorganization internalizes multiple transient receptor potential channels and blocks calcium entry into human neutrophils
intercellular adhesion molecule-1 mediates cellular cross-talk between parenchymal and immune cells after lipopolysaccharide neutralization
sustained il-12 signaling is required for th1 development
corticosteroids regulate epithelial cell differentiation and hassall body formation in the human thymus
impaired clearance of apoptotic cells induces the activation of autoreactive anti-sm marginal zone and b-1 b cells
gene expression profiling provides insight into the pathophysiology of chronic granulomatous disease
determinants of antileukemia effects of allogeneic nk cells
a novel mechanism of alternative promoter and splicing regulates the epitope generation of tumor antigen cml66-l
antibody cross-reactivity between myelin oligodendrocyte glycoprotein and the milk protein butyrophilin in multiple sclerosis 1,
distortion of the self-reactive igg antibody repertoire in multiple sclerosis as a new diagnostic tool
cd4 + t cells mediate murine syngeneic graft-versus-host disease-associated colitis
nf- b p65 antagonizes il-4 induction by c- maf in minimal change nephrotic syndrome
thymic selection and peripheral activation of cd8 t cells by the same class i mhc/peptide complex
a cd91-positive subset of cd11c + blood dendritic cells: characterization of the apc that functions to enhance adaptive immune responses against cd91-targeted antig..
a major b cell epitope present on the apoptotic but not the intact form of the u1-70-kda ribonucleoprotein autoantigen
cutting edge: anthrax lethal toxin inhibits activation of ifn-regulatory factor 3 by lipopolysaccharide
cutting edge: nf- b2 is a negative regulator of dendritic cell function
cutting edge: novel priming of tumor-specific immunity by nkg2d-triggered nk cell-mediated tumor rejection and th1-independent cd4 + t cell pathway
cutting edge: baff regulates cd21/35 and cd23 expression independent of its b cell survival function
differential role of ccr2 in islet and heart allograft rejection: tissue specificity of chemokine/chemokine receptor function in vivo
enhanced priming of antigen-specific ctls in vivo by embryonic stem cell-derived dendritic cells expressing chemokine along with antigenic protein: application to a..
cd7 and cd28 are required for murine cd4 + cd25 + regulatory t cell homeostasis and prevention of thyroiditis
rosmarinic acid induces p56 lck -dependent apoptosis in jurkat and peripheral t cells via mitochondrial pathway independent from fas/fas ligand interaction
tcr-independent and caspase-independent apoptosis of murine thymocytes by cd24 cross-linking
marginal zone, but not follicular b cells, are potent activators of naive cd4 t cells
tnf deficiency fails to protect baff transgenic mice against autoimmunity and reveals a predisposition to b cell lymphoma
progressive surface b cell antigen receptor down-regulation accompanies efficient development of antinuclear antigen b cells to mature, follicular phenotype
tgf- 1 plays an important role in the mechanism of cd4 + cd25 + regulatory t cell activity in both humans and mice
ephrin-a1 suppresses th2 cell activation and provides a regulatory link to lung epithelial cells
central tolerance to self-antigen expressed by cortical epithelial cells
dendritic cell immunization route determines cd8 + t cell trafficking to inflamed skin: role for tissue microenvironment and dendritic cells in establishment of t c..
turnover and proliferation of nk cells in steady state and lymphopenic conditions
mhc class ii molecules play a role in the selection of autoreactive class i-restricted cd8 t cells that are essential contributors to type 1 diabetes development in..
the il-12 signature: nk cell terminal cd56 +high stage and effector functions
innate immune discrimination of apoptotic cells: repression of proinflammatory macrophage transcription is coupled directly to specific recognition
dual role of ccr2 during initiation and progression of collagen-induced arthritis: evidence for regulatory activity of ccr2 + t cells
nkp44 triggers nk cell activation through dap12 association that is not influenced by a putative cytoplasmic inhibitory sequence
invariant chain and the mhc class ii cytoplasmic domains regulate localization of mhc class ii molecules to lipid rafts in tumor cell-based vaccines
an altered self-peptide with superagonist activity blocks a cd8-mediated mouse model of type 1 diabetes
alloantigen-induced cd25 + cd4 + regulatory t cells can develop in vivo from cd25 - cd4 + precursors in a thymus-independent process
tcr vaccines against a murine t cell lymphoma: a primary role for antibodies of the igg2c class in tumor protection
regulation of autoimmune diabetes by complete freunds adjuvant is mediated by nk cells
dissociation of nkt stimulation, cytokine induction, and nk activation in vivo by the use of distinct tcr-binding ceramides
il-12p70-dependent th1 induction by human b cells requires combined activation with cd40 ligand and cpg dna
early growth response gene 3 regulates thymocyte proliferation during the transition from cd4 - cd8 - to cd4 + cd8 +
the susceptibility to experimental myasthenia gravis of stat6 -/- and stat4 -/- balb/c mice suggests a pathogenic role of th1 cells
the cell surface-localized heat shock protein 70 epitope tkd induces migration and cytolytic activity selectively in human nk cells
a switch in costimulation from cd28 to 4-1bb during primary versus secondary cd8 t cell response to influenza in vivo
antigen-specific inhibition of cd8 + t cell response by immature myeloid cells in cancer is mediated by reactive oxygen species
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