cutting edge: sds-stable fas microaggregates: an early event of fas activation occurring with agonistic anti-fas antibody but not with fas ligand
cutting edge: increased nk cell activity in hiv-1-exposed but uninfected vietnamese intravascular drug users
cutting edge: efficient mhc class i cross-presentation during early vaccinia infection requires the transfer of proteasomal intermediates between antigen donor and ..
cutting edge: transplantation tolerance through enhanced ctla-4 expression
cutting edge: self-peptides drive the peripheral expansion of cd4 + cd25 + regulatory t cells
cutting edge: tcr contacts as anchors: effects on affinity and hla-dm stability
requirements for t cell-polarized tubulation of class ii + compartments in dendritic cells
cd4 + t cell-associated pathophysiology critically depends on cd18 gene dose effects in a murine model of psoriasis
cd40, but not cd154, expression on b cells is necessary for optimal primary b cell responses
tethering of apoptotic cells to phagocytes through binding of cd47 to src homology 2 domain-bearing protein tyrosine phosphatase substrate-1
il-2 is not required for the initiation of cd8 t cell cycling but sustains expansion
aberrant extracellular and dendritic cell (dc) surface expression of heat shock protein (hsp)70 in the rheumatoid joint: possible mechanisms of hsp/dc-mediated cros..
peroxisome proliferator-activated receptor- -deficient heterozygous mice develop an exacerbated neural antigen-induced th1 response and experimental allergic enceph..
tnf receptor-associated factor 6 deficiency during hemopoiesis induces th2-polarized inflammatory disease
human cd25 + regulatory t cells maintain immune tolerance to nickel in healthy, nonallergic individuals
in vitro differentiation from naive to mature e-selectin binding cd4 t cells: acquisition of skin-homing properties occurs independently of cutaneous lymphocyte ant..
ultraviolet b radiation-induced cell death: critical role of ultraviolet dose in inflammation and lupus autoantigen redistribution
human erbb-2 (her-2) transgenic mice: a model system for testing her-2 based vaccines
increased severity of murine lupus in female mice is due to enhanced expansion of pathogenic t cells
role of antiproliferative b cell translocation gene-1 as an apoptotic sensitizer in activation-induced cell death of brain microglia
mhc class ii-peptide complexes in dendritic cell lipid microdomains initiate the cd4 th1 phenotype
estradiol treatment redirects the isotype of the autoantibody response and prevents the development of autoimmune arthritis
the duration of signaling through cd40 directs biological ability of dendritic cells to induce antitumor immunity
maturation of dendritic cell 2 phenotype by a helminth glycan uses a toll-like receptor 4-dependent mechanism
dendritic cell-induced activation of adaptive and innate antitumor immunity
distinct effects of stat5 activation on cd4 + and cd8 + t cell homeostasis: development of cd4 + cd25 + regulatory t cells versus cd8 + memory t cells
systemic administration of il-18 promotes diabetes development in young nonobese diabetic mice
ligation of cd27 on b cells in vivo during primary immunization enhances commitment to memory b cell responses
fibronectin-associated fas ligand rapidly induces opposing and time-dependent effects on the activation and apoptosis of t cells
tolerance through indifference: autoreactive b cells to the nuclear antigen la show no evidence of tolerance in a transgenic model
il-4 and il-13 induce socs-1 gene expression in a549 cells by three functional stat6-binding motifs located upstream of the transcription initiation site
vaccination with plasmid dna activates dendritic cells via toll-like receptor 9 (tlr9) but functions in tlr9-deficient mice
control of nkt cell differentiation by tissue-specific microenvironments
cd19 function in early and late b cell development. ii. cd19 facilitates the pro-b/pre-b transition
cd4 + /cd25 + regulatory cells inhibit activation of tumor-primed cd4 + t cells with ifn- -dependent antiangiogenic activity, as well as long-lasting tumor immunity..
dendritic cells charged with apoptotic tumor cells induce long-lived protective cd4 + and cd8 + t cell immunity against b16 melanoma
promiscuity of mhc class ib-restricted t cell responses
molecular cloning and immunologic characterization of a novel cdna coding for progesterone-induced blocking factor
simultaneous prediction of binding capacity for multiple molecules of the hla b44 supertype
altered regulation of fc rii on aged follicular dendritic cells correlates with immunoreceptor tyrosine-based inhibition motif signaling in b cells and reduced germ..
function of brutons tyrosine kinase during b cell development is partially independent of its catalytic activity
ox40-mediated memory t cell generation is tnf receptor-associated factor 2 dependent
ikaros family members from the agnathan myxine glutinosa and the urochordate oikopleura dioica : emergence of an essential transcription factor for adaptive immunity
inhibition of nf- b activation and its target genes by heparin-binding epidermal growth factor-like growth factor
allogeneic t cells treated with amotosalen prevent lethal cytomegalovirus disease without producing graft-versus-host disease following bone marrow transplantation
activation of antigen-specific cd8 t cells results in minimal killing of bystander bacteria
nk cells respond to pulmonary infection with mycobacterium tuberculosis, but play a minimal role in protection
human c-reactive protein does not protect against acute lipopolysaccharide challenge in mice
cross-talk in the innate immune system: neutrophils instruct recruitment and activation of dendritic cells during microbial infection
sustained nitric oxide delivery delays nitric oxide-dependent apoptosis in macrophages: contribution to the physiological function of activated macrophages
il-1r-associated kinase 4 is required for lipopolysaccharide- induced activation of apc
curcumin suppresses janus kinase-stat inflammatory signaling through activation of src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia
cyclooxygenase-2-derived e prostaglandins down-regulate matrix metalloproteinase-1 expression in fibroblast-like synoviocytes via inhibition of extracellular signal..
fc riiib allele-sensitive release of -defensins: anti-neutrophil cytoplasmic antibody-induced release of chemotaxins
activation of endothelial extracellular signal-regulated kinase is essential for neutrophil transmigration: potential involvement of a soluble neutrophil factor in ..
mac-1, but not lfa-1, uses intercellular adhesion molecule-1 to mediate slow leukocyte rolling in tnf- -induced inflammation
regulation and phenotype of an innate th1 cell: role of cytokines and the p38 kinase pathway
fc ri signaling of mast cells activates intracellular production of hydrogen peroxide: role in the regulation of calcium signals
increased acute inflammation, leukotriene b 4 -induced chemotaxis, and signaling in mice deficient for g protein-coupled receptor kinase
endothelial cells proactively form microvilli-like membrane projections upon intercellular adhesion molecule 1 engagement of leukocyte lfa-1
toll-like receptor 2 pathway drives streptococcal cell wall-induced joint inflammation: critical role of myeloid differentiation factor 8
apoptosis-associated speck-like protein containing a caspase recruitment domain is a regulator of procaspase-1 activation
proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms
suppression of immune induction of collagen-induced arthritis in il-17-deficient mice
alterations in granule matrix and cell surface of focal adhesion kinase-deficient mast cells
toll-like receptor-2, but not toll-like receptor-4, is essential for development of oviduct pathology in chlamydial genital tract infection
aberrant inflammation and lethality to septic peritonitis in mice lacking stat3 in macrophages and neutrophils
inhibition of th1- and th2-mediated airway inflammation by the sphingosine 1-phosphate receptor agonist fty72
placental cell expression of hla-g2 isoforms is limited to the invasive trophoblast phenotype
b-1 b cells mediate required early t cell recruitment to elicit protein-induced delayed-type hypersensitivity
mechanisms of spontaneous resolution versus fibrosis in granulomatous experimental autoimmune thyroiditis
the plant lectin wheat germ agglutinin inhibits the binding of pemphigus foliaceus autoantibodies to desmoglein 1 in a majority of patients and prevents pathomechan..
activity and safety of ctla-4 blockade combined with vaccines in cynomolgus macaques
chromatin specificity of anti-double-stranded dna antibodies and a role for arg residues in the third complementarity-determining region of the heavy chain
immune modulation in multiple sclerosis patients treated with the pregnancy hormone estriol
injection of immature dendritic cells into adjuvant-treated skin obviates the need for ex vivo maturation
identification of five new hla-b3501-restricted epitopes derived from common melanoma-associated antigens, spontaneously recognized by tumor-infiltrating lymphocytes
differential regulation of peripheral cd4 + t cell tolerance induced by deletion and tcr revision
cutting edge: cias1/cryopyrin/pypaf1/nalp3/ caterpiller 1.1 is an inducible inflammatory mediator with nf- b suppressive properties
cutting edge: stimulation with the cognate self-antigen induces expression of the ly49a receptor on self-reactive t cells which modulates their responsiveness
cutting edge: cd4 + t cell help can be essential for primary cd8 + t cell responses in vivo
cutting edge: a potent adjuvant effect of ligand to receptor activator of nf- b gene for inducing antigen-specific cd8 + t cell response by dna and viral vector vac..
deletion of naive cd8 t cells requires persistent antigen and is not programmed by an initial signal from the tolerogenic apc
homing to nonlymphoid tissues is not necessary for effector th1 cell differentiation
human dendritic cells express the il-18r and are chemoattracted to il-18
b lymphocyte development in rabbit: progenitor b cells and waning of b lymphopoiesis
evidence for a ligand-mediated positive selection signal in differentiation to a mature b cell
proinflammatory actions of thromboxane receptors to enhance cellular immune responses
effective genetic vaccination with a widely shared endogenous retroviral tumor antigen requires cd40 stimulation during tumor rejection phase
newly activated t cells promote maturation of bystander dendritic cells but not il-12 production
phosphodiesterase 7a-deficient mice have functional t cells
cyclic nucleotides promote monocyte differentiation toward a dc-sign + (cd209) intermediate cell and impair differentiation into dendritic cells
il-15 and cognate antigen successfully expand de novo-induced human antigen-specific regulatory cd4 + t cells that require antigen-specific activation for suppression
genetic complementation in female (bxsb x nzw)f 2 mice
differential effects of il-1 and il-1 on tumorigenicity patterns and invasiveness
ebv-induced molecule 1 ligand chemokine (elc/ccl19) promotes ifn- -dependent antitumor responses in a lung cancer model
mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody
cd40-induced aggregation of mhc class ii and cd80 on the cell surface leads to an early enhancement in antigen presentation
the interaction of t cells with activated macrophages is a property of the v 1 subset
the selection of marginal zone b cells differs from that of b-1a cells
alloreactive cd4 t cell activation in vivo: an autonomous function of the indirect pathway of alloantigen presentation
the male minor transplantation antigen preferentially activates recipient cd4 + t cells through the indirect presentation pathway in vivo
neuronal repellent slit2 inhibits dendritic cell migration and the development of immune responses
cd43 modulates severity and onset of experimental autoimmune encephalomyelitis
hypoxia-inducible factor regulates survival of antigen receptor-driven t cells
cmrf-35-like molecule-1, a novel mouse myeloid receptor, can inhibit osteoclast formation
nasal vaccination with myelin oligodendrocyte glycoprotein reduces stroke size by inducing il-10-producing cd4 + t cells
reduced switching in scid b cells is associated with altered somatic mutation of recombined s regions
expression and characterization of the c345c/ntr domains of complement components c3 and c5
identification of a critical ig-like domain in il-18 receptor and characterization of a functional il-18 receptor complex
regulation of inducible nitric oxide synthase expression by p300 and p50 acetylation
critical role for the oct-2/oca-b partnership in ig-secreting cells
identification, isolation, and culture of hla-a2-specific b lymphocytes using mhc class i tetramers
the b12/23 restriction is critically dependent on recombination signal nonamer and spacer sequences
transcriptional regulation of ilt family receptors
transcriptional regulation of src homology 2 domain-containing leukocyte phosphoprotein of 76 kda: dissection of key promoter elements
neutrophil gelatinase-associated lipocalin is up-regulated in human epithelial cells by il-1, but not by tnf-
the protein made from a common allele of kir3dl1 ( 3dl1004 ) is poorly expressed at cell surfaces due to substitution at positions 86 in ig domain 0 and 182 in ig d..
anti-cd8 antibodies can inhibit or enhance peptide-mhc class i (pmhci) multimer binding: this is paralleled by their effects on ctl activation and occurs in the abs..
homotypic secretory vesicle fusion induced by the protein tyrosine phosphatase meg2 depends on polyphosphoinositides in t cells
basal chromatin modification at the il-4 gene in helper t cells
soluble forms of toll-like receptor (tlr)2 capable of modulating tlr2 signaling are present in human plasma and breast milk
the antimicrobial peptide ll-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor
outer membrane protein a from klebsiella pneumoniae activates bronchial epithelial cells: implication in neutrophil recruitment
leishmania -induced inhibition of macrophage antigen presentation analyzed at the single-cell level
il-8-mediated cell migration in endothelial cells depends on cathepsin b activity and transactivation of the epidermal growth factor receptor
proinflammatory cytokines dominate the early immune response to filarial parasites
ctl are inactivated by herpes simplex virus-infected cells expressing a viral protein kinase
salmonella rapidly kill dendritic cells via a caspase-1- dependent mechanism
cd154 activates macrophage antimicrobial activity in the absence of ifn- through a tnf- -dependent mechanism
human cytomegalovirus-encoded us2 differentially affects surface expression of mhc class i locus products and targets membrane-bound, but not soluble hla-g1 for deg..
mycobacterium avium inhibition of ifn- signaling in mouse macrophages: toll-like receptor 2 stimulation increases expression of dominant-negative stat1 by mrna stab..
induction of cd8 + t cells to an hiv-1 antigen through a prime boost regimen with heterologous e1-deleted adenoviral vaccine carriers
hyaluronic acid or tnf- plus fibronectin triggers granulocyte macrophage-colony-stimulating factor mrna stabilization in eosinophils yet engages differential intrac..
role of monocyte chemotactic protein-1/cc chemokine ligand 2 on t lymphocyte trafficking during inflammation induced by lipopolysaccharide or mycobacterium bovis ba..
surface translocation of pactolus is induced by cell activation and death, but is not required for neutrophil migration and function
differential activation of formyl peptide receptor-like 1 by peptide ligands
shedding of the type ii il-1 decoy receptor requires a multifunctional aminopeptidase, aminopeptidase regulator of tnf receptor type 1 shedding
activation of toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human defensin-2
peroxisome proliferator activator receptor- ligands, 15-deoxy- 12,14 -prostaglandin j 2 and ciglitazone, reduce systemic inflammation in polymicrobial sepsis by mod..
among cxcr3 chemokines, ifn- -inducible protein of 10 kda (cxc chemokine ligand (cxcl) 10) but not monokine induced by ifn- (cxcl9) imprints a pattern for the subse..
granulocyte-macrophage colony-stimulating factor is a chemoattractant cytokine for human neutrophils: involvement of the ribosomal p70 s6 kinase signaling pathway
reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediators
il-12 p40 homodimer-dependent macrophage chemotaxis and respiratory viral inflammation are mediated through il-12 receptor 1
adenovirus-transduced dendritic cells injected into skin or lymph node prime potent simian immunodeficiency virus-specific t cell immunity in monkeys
a novel protein highly expressed in testis is overexpressed in systemic sclerosis fibroblasts and targeted by autoantibodies
evasion from nk cell immunity by mhc class i chain-related molecules expressing colon adenocarcinoma
cross-priming of diabetogenic t cells dissociated from ctl-induced shedding of cell autoantigens
influence of mhc class ii in susceptibility to beryllium sensitization and chronic beryllium disease
trachea allograft class i molecules directly activate and retain cd8 + t cells that cause obliterative airways disease
blocking the monocyte chemoattractant protein-1/ccr2 chemokine pathway induces permanent survival of islet allografts through a programmed death-1 ligand-1-dependen..
estrogen receptor mediates estrogens immune protection in autoimmune disease
tumor vaccination after allogeneic bone marrow cell reconstitution of the nonmyeloablatively conditioned tumor-bearing murine host
paradoxical dampening of anti-islet self-reactivity but promotion of diabetes by ox40 ligand
protective immunity induced with malaria vaccine, rts,s, is linked to plasmodium falciparum circumsporozoite protein-specific cd4 + and cd8 + t cells producing ifn-
reconstitution of virus-specific cd4 proliferative responses in pediatric hiv-1 infection