bacterial lipopolysaccharide signaling through toll-like receptor 4 suppresses asthma-like responses via nitric oxide synthase 2 activity
il-18 enhances collagen-induced arthritis by recruiting neutrophils via tnf- and leukotriene b 4
matrix metalloproteinase-9-mediated dendritic cell recruitment into the airways is a critical step in a mouse model of asthma
the rhoa effector mdia is induced during t cell activation and regulates actin polymerization and cell migration in t lymphocytes
inhibition of neutrophil apoptosis by type 1 ifn depends on cross-talk between phosphoinositol 3-kinase, protein kinase c-, and nf- b signaling pathways
modulation of cd11b/cd18 adhesive activity by its extracellular, membrane-proximal regions
clara cell secretory protein modulates lung inflammatory and immune responses to respiratory syncytial virus infection
trail-r2 (dr5) mediates apoptosis of synovial fibroblasts in rheumatoid arthritis
induction of human t lymphocyte cytotoxicity and inhibition of tumor growth by tumor-specific diabody-based molecules secreted from gene-modified bystander cells
a second step of chemotaxis after transendothelial migration: keratinocytes undergoing apoptosis release ifn- -inducible protein 10, monokine induced by ifn-, and i..
osteopontin (eta-1) and fibroblast growth factor-2 cross-talk in angiogenesis
hiv-1 vaccination administered intramuscularly can induce both systemic and mucosal t cell immunity in hiv-1-uninfected individuals
differential susceptibility to staphylococcal superantigen (ssag)-induced apoptosis of cd4 + t cells from atopic dermatitis patients and healthy subjects: the inhib..
a role for the lymphotoxin/light axis in the pathogenesis of murine collagen-induced arthritis
recombinant tcr ligand induces tolerance to myelin oligodendrocyte glycoprotein 35-55 peptide and reverses clinical and histological signs of chronic experimental a..
inhibition of graft-versus-host disease by double-negative regulatory t cells
il-3 acts directly on osteoclast precursors and irreversibly inhibits receptor activator of nf- b ligand-induced osteoclast differentiation by diverting the cells t..
dendritic cells support sequential reprogramming of chemoattractant receptor profiles during naive to effector t cell differentiation
cc chemokine receptor 9 expression defines a subset of peripheral blood lymphocytes with mucosal t cell phenotype and th1 or t-regulatory 1 cytokine profile
cd28 and inducible costimulatory protein src homology 2 binding domains show distinct regulation of phosphatidylinositol 3-kinase, bcl-x l, and il-2 expression in p..
cutting edge: rapid in vivo ctl activity by polyoma virus-specific effector and memory cd8 + t cells
inhibition of ifn- -induced class ii transactivator expression by a 19-kda lipoprotein from mycobacterium tuberculosis : a potential mechanism for immune evasion
genetic disassociation of autoimmunity and resistance to costimulation blockade-induced transplantation tolerance in nonobese diabetic mice
peroxisome proliferator-activated receptor negatively regulates t-bet transcription through suppression of p38 mitogen-activated protein kinase activation
development of infectious tolerance after donor-specific transfusion and rat heart transplantation
plasmacytoid dendritic cell-derived ifn- induces tnf-related apoptosis-inducing ligand/apo-2l-mediated antitumor activity by human monocytes following cpg oligodeox..
a mage-3 peptide presented by hla-dr1 to cd4 + t cells that were isolated from a melanoma patient vaccinated with a mage-3 protein
cutting edge: class i presentation of host peptides following hiv infection
t cell receptor revision does not solely target recent thymic emigrants
nk cells regulate cd4 responses prior to antigen encounter
local cooperation dominates over competition between cd4 + t cells of different antigen/mhc specificity
the requirements for fas-associated death domain signaling in mature t cell activation and survival
tnf- induces tyrosine phosphorylation and recruitment of the src homology protein-tyrosine phosphatase 2 to the gp130 signal-transducing subunit of the il-6 recepto..
activation of protein kinase c by ifn-
cutting edge: rapid in vivo killing by memory cd8 t cells
a novel instance of class i modification ( cim ) affecting two of three rat class i rt1-a molecules within one mhc haplotype
ifn- induces the human il-10 gene by recruiting both ifn regulatory factor 1 and stat3
class ia mhc-deficient balb/c mice generate cd8 + t cell-mediated protective immunity against listeria monocytogenes infection
nad(p)h oxidase 1, a product of differentiated colon epithelial cells, can partially replace glycoprotein 91 phox in the regulated production of superoxide by phago..
greater cd8 + tcr heterogeneity and functional flexibility in hiv-2 compared to hiv-1 infection
plasmodium chabaudi chabaudi infection in mice induces strong b cell responses and striking but temporary changes in splenic cell distribution
cutting edge: link between innate and adaptive immunity: toll-like receptor 2 internalizes antigen for presentation to cd4 + t cells and could be an efficient vacci..
a single intratracheal dose of the growth factor fms-like tyrosine kinase receptor-3 ligand induces a rapid differential increase of dendritic cells and lymphocyte ..
identification of a 3 receptor- and mast cell-dependent and -independent components of adenosine-mediated airway responsiveness in mice
activation of murine lung mast cells by the adenosine a 3 receptor
captopril prevents experimental autoimmune myocarditis
-melanocyte-stimulating hormone inhibits allergic airway inflammation
distinct role of zap-70 and src homology 2 domain-containing leukocyte protein of 76 kda in the prolonged activation of extracellular signal-regulated protein kinas..
vulnerability of human neurons to t cell-mediated cytotoxicity
the uterine nk cell population requires il-15 but these cells are not required for pregnancy nor the resolution of a listeria monocytogenes infection
identification of circulating fibrocytes as precursors of bronchial myofibroblasts in asthma
mast cells in airway hyporesponsive c3h/hej mice express a unique isoform of the signaling protein ras guanine nucleotide releasing protein 4 that is unresponsive t..
a site on laminin 5, aqarsaaskvkvsmkf, induces inflammatory cell production of matrix metalloproteinase-9 and chemotaxis
identification and isolation of dominant susceptibility loci for pristane-induced arthritis
direct binding of toll-like receptor 2 to zymosan, and zymosan-induced nf- b activation and tnf- secretion are down-regulated by lung collectin surfactant protein a
bcl6 is a transcriptional repressor for the il-18 gene
thymic export function and t cell homeostasis in patients with relapsing remitting multiple sclerosis
persistent infection of human microvascular endothelial cells by coxsackie b viruses induces increased expression of adhesion molecules
investigating the impact of helminth products on immune responsiveness using a tcr transgenic adoptive transfer system
selective unresponsiveness to conformational b cell epitopes of the myelin oligodendrocyte glycoprotein in h-2 b mice
rat and human myelin oligodendrocyte glycoproteins induce experimental autoimmune encephalomyelitis by different mechanisms in c57bl/6 mice
more stringent conditions of plasmid dna vaccination are required to protect grafted versus endogenous islets in nonobese diabetic mice
relationships among murine cd11c high dendritic cell subsets as revealed by baseline gene expression patterns
longitudinal assessment of changes in hiv-specific effector activity in hiv-infected patients starting highly active antiretroviral therapy in primary infection
short term administration of costimulatory blockade and cyclophosphamide induces remission of systemic lupus erythematosus nephritis in nzb/w f 1 mice by a mechanis..
cutting edge: granzymes a and b are not essential for perforin-mediated tumor rejection
cutting edge: a chemical genetic system for the analysis of kinases regulating t cell development
cutting edge: tcr gene is frequently rearranged in adult b lymphocytes
cutting edge: mhc class ii-restricted peptides containing the inflammation-associated marker 3-nitrotyrosine evade central tolerance and elicit a robust cell-mediat..
cutting edge: protective cell-mediated immunity to listeria monocytogenes in the absence of myeloid differentiation factor 88
cutting edge: the conversion of arginine to citrulline allows for a high-affinity peptide interaction with the rheumatoid arthritis-associated hla-drb10401 mhc clas..
cutting edge: sanglifehrin a, a novel cyclophilin-binding immunosuppressant blocks bioactive il-12 production by human dendritic cells
cutting edge: germinal centers formed in the absence of b cell-activating factor belonging to the tnf family exhibit impaired maturation and function
a high endothelial venule secretory protein, mac25/angiomodulin, interacts with multiple high endothelial venule-associated molecules including chemokines
fc rs modulate cytotoxicity of anti-fas antibodies: implications for agonistic antibody-based therapeutics
tumor cells engineered with il-12 and il-15 genes induce protective antibody responses in nude mice
blocking 4-1bb/4-1bb ligand interactions prevents herpetic stromal keratitis
increased resistance of lfa-1-deficient mice to lipopolysaccharide-induced shock/liver injury in the presence of tnf- and il-12 is mediated by il-10: a novel role f..
pattern recognition by trem-2: binding of anionic ligands
antitumor and antimetastatic activity of il-23
il-21 activates both innate and adaptive immunity to generate potent antitumor responses that require perforin but are independent of ifn-
homeostasis of naive and memory cd4 + t cells: il-2 and il-7 differentially regulate the balance between proliferation and fas-mediated apoptosis
thyrotropin-mediated repression of class ii trans -activator expression in thyroid cells: involvement of stat3 and suppressor of cytokine signaling
c-jun n-terminal kinase negatively regulates lipopolysaccharide-induced il-12 production in human macrophages: role of mitogen-activated protein kinase in glutathio..
cd4 + t cells from (new zealand black x new zealand white)f 1 lupus mice and normal mice immunized against apoptotic nucleosomes recognize similar th cell epitopes ..
effects of il-7 on early human thymocyte progenitor cells in vitro and in scid-hu thy/liv mice
attrition of virus-specific memory cd8 + t cells during reconstitution of lymphopenic environments
febrile temperatures attenuate il-1 release by inhibiting proteolytic processing of the proform and influence th1/th2 balance by favoring th2 cytokines
p-selectin enhances generation of cd14 + cd16 + dendritic-like cells and inhibits macrophage maturation from human peripheral blood monocytes
late immature b cells (igm high igd neg ) undergo a light chain receptor editing response to soluble self-antigen
il-15-mediated induction of lfa-1 is a late step required for cytotoxic differentiation of human nk cells from cd34 + lin - bone marrow cells
thy-1 signaling in the context of costimulation provided by dendritic cells provides signal 1 for t cell proliferation and cytotoxic effector molecule expression, b..
immune modulation by silencing il-12 production in dendritic cells using small interfering rna 1,
in vivo ligation of cd40 enhances priming against the endogenous tumor antigen and promotes cd8 + t cell effector function in sv40 t antigen transgenic mice
regulation of murine inflammatory bowel disease by cd25 + and cd25 - cd4 + glucocorticoid-induced tnf receptor family-related gene + regulatory t cells
role of the phosphatidylinositol 3 kinase-akt pathway in the regulation of il-10 and il-12 by porphyromonas gingivalis lipopolysaccharide
gr-1 + myeloid cells lacking t cell protein tyrosine phosphatase inhibit lymphocyte proliferation by an ifn- - and nitric oxide-dependent mechanism
induction of autoantigen-specific th2 and tr1 regulatory t cells and modulation of autoimmune diabetes
cd49d overexpression and t cell autoimmunity
the slc11a1 ( nramp1 ) gene controls efficacy of mycobacterial treatment of allergic asthma
nf- b1 p50 is required for blys attenuation of apoptosis but dispensable for processing of nf- b2 p100 to p52 in quiescent mature b cells
initiation and limitation of ly-49a nk cell receptor acquisition by t cell factor-1
induction of cd4 + t cell apoptosis as a consequence of impaired cytoskeletal rearrangement in uvb-irradiated dendritic cells
t cell glycolipid-enriched membrane domains are constitutively assembled as membrane patches that translocate to immune synapses
regulatory roles of il-2 and il-4 in h4/inducible costimulator expression on activated cd4 + t cells during th cell development
innate immunity together with duration of antigen persistence regulate effector t cell induction
characterization of transcriptional regulation during negative selection in vivo
modular organization of the carboxyl-terminal, globular head region of human c1q a, b, and c chains
functional cooperation of simian virus 40 promoter factor 1 and ccaat/enhancer-binding protein and in lipopolysaccharide-induced gene activation of il-10 in mouse m..
increase of tcr v accessibility within e regulatory region influences its recombination frequency but not allelic exclusion
hyperconservation of the n -formyl peptide binding site of m3 : evidence that m3 is an old eutherian molecule with conserved recognition of a pathogen-associated mo..
t cell antagonism is functionally uncoupled from the 21- and 23-kda tyrosine-phosphorylated tcr subunits
editing of an immunodominant epitope of glutamate decarboxylase by hla-dm
linker for activation of t cells, -associated protein-70, and src homology 2 domain-containing leukocyte protein-76 are required for tcr-induced microtubule-organiz..
stalk region of -chain enhances the coreceptor function of cd8
characterization of pig-tailed macaque classical mhc class i genes: implications for mhc evolution and antigen presentation in macaques
inhibition of constitutive nf- b activation in mantle cell lymphoma b cells leads to induction of cell cycle arrest and apoptosis
maintenance of long term -herpesvirus b cell latency is dependent on cd40-mediated development of memory b cells
susceptibility to experimental lyme arthritis correlates with kc and monocyte chemoattractant protein-1 production in joints and requires neutrophil recruitment via..
effects of human cytomegalovirus infection on ligands for the activating nkg2d receptor of nk cells: up-regulation of ul16-binding protein (ulbp)1 and ulbp2 is coun..
sepsis induces apoptosis and profound depletion of splenic interdigitating and follicular dendritic cells
enhanced recognition of human nk receptors after influenza virus infection
identification of uteroglobin-related protein 1 and macrophage scavenger receptor with collagenous structure as a lung-specific ligand-receptor pair
inactivation of human -defensins 2 and 3 by elastolytic cathepsins
gm-csf restores innate, but not adaptive, immune responses in glucocorticoid-immunosuppressed human blood in vitro
dependence of il-4, il-13, and nematode-induced alterations in murine small intestinal smooth muscle contractility on stat6 and enteric nerves
sublethal hyperoxia impairs pulmonary innate immunity
rho kinase promotes alloimmune responses by regulating the proliferation and structure of t cells
early self-regulatory mechanisms control the magnitude of cd8 + t cell responses against liver stages of murine malaria
colitogenic th1 cells are present in the antigen-experienced t cell pool in normal mice: control by cd4 + regulatory t cells and il-10
inhibition of ifn- -mediated inducible nitric oxide synthase induction by the peroxisome proliferator-activated receptor agonist, 15-deoxy- 12,14 -prostaglandin j 2..
amplification mechanisms of inflammation: paracrine stimulation of arachidonic acid mobilization by secreted phospholipase a 2 is regulated by cytosolic phospholipa..
inhibitory effects of surfactant protein a on surfactant phospholipid hydrolysis by secreted phospholipases a 2