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免疫学杂志2003年第04期封面 购买


cutting edge: a toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling
cutting edge: cd40-induced expression of recombination activating gene (rag) 1 and rag2: a mechanism for the generation of autoaggressive t cells in the periphery
il-9 enhances the growth of human mast cell progenitors under stimulation with stem cell factor
cpg-a oligonucleotides induce a monocyte-derived dendritic cell-like phenotype that preferentially activates cd8 t cells
expression of a constitutively active stat6 in vivo alters lymphocyte homeostasis with distinct effects in t and b cells
gangliosides from human melanoma tumors impair dendritic cell differentiation from monocytes and induce their apoptosis
il-4 potentiates activated t cell apoptosis via an il-2-dependent mechanism
presentation by recycling mhc class ii molecules of an influenza hemagglutinin-derived epitope that is revealed in the early endosome by acidification
two developmentally distinct populations of dendritic cells inhabit the adult mouse thymus: demonstration by differential importation of hematogenous precursors und..
prevention of autoantibody-mediated graves-like hyperthyroidism in mice with il-4, a th2 cytokine
the mhc class i-like igg receptor controls perinatal igg transport, igg homeostasis, and fate of igg-fc-coupled drugs
the b cell coreceptor cd22 associates with ap50, a clathrin-coated pit adapter protein, via tyrosine-dependent interaction
the mechanism of cd47-dependent killing of t cells: heterotrimeric g i -dependent inhibition of protein kinase a
murine flt3 ligand expands distinct dendritic cells with both tolerogenic and immunogenic properties
toll-like receptor 3 mediates a more potent antiviral response than toll-like receptor 4
activated, but not resting, t cells can be recognized and killed by syngeneic nk cells
ligation of retinoic acid receptor regulates negative selection of thymocytes by inhibiting both dna binding of nur77 and synthesis of bim
il-10 mediates sigma 1 receptor-dependent suppression of antitumor immunity
infections that induce autoimmune diabetes in bbdr rats modulate cd4 + cd25 + t cell populations 1,
role of mhc class i in immune surveillance of mitochondrial dna integrity
requirement of species-specific interactions for the activation of human t cells by pamidronate
the molecular basis for the lack of immunostimulatory activity of vertebrate dna
more is not necessarily better: prozone-like effects in passive immunization with igg
galectin-9 induces apoptosis through the calcium-calpain-caspase-1 pathway
b7-h1 (programmed death-1 ligand) on dendritic cells is involved in the induction and maintenance of t cell anergy
tgf 1 inhibits ca 2+ -calcineurin-mediated activation in thymocytes
ss-a/ro52, an autoantigen involved in cd28-mediated il-2 production
sphingosine-1-phosphate receptor agonism impairs the efficiency of the local immune response by altering trafficking of naive and antigen-activated cd4 + t cells
b cell complement receptor 2 transfer reaction
the possible role of tgf- -induced suppressors of cytokine signaling expression in osteoclast/macrophage lineage commitment in vitro
lipopolysaccharide promotes the survival of osteoclasts via toll-like receptor 4, but cytokine production of osteoclasts in response to lipopolysaccharide is differ..
conservation of nonpeptide antigen recognition by rhesus monkey v 2v 2 t cells
atm is not required in somatic hypermutation of v h, but is involved in the introduction of mutations in the switch µ region
transactivation of gp130 in myeloma cells
c-rel is required for chromatin remodeling across the il-2 gene promoter
regulation of the human fc ri -chain distal promoter
a new model of sheep ig diversification: shifting the emphasis toward combinatorial mechanisms and away from hypermutation
dm loss in k haplotype mice reveals isotype-specific chaperone requirements
actin tyrosine dephosphorylation by the src homology 1-containing protein tyrosine phosphatase is essential for actin depolymerization after membrane igm cross-link..
investigation of early events in fc ri-mediated signaling using a detailed mathematical model
depletion of neutrophils in il-10 -/- mice delays clearance of gastric helicobacter infection and decreases the th1 immune response to helicobacter
the hypervariable region of anaplasma marginale major surface protein 2 (msp2) contains multiple immunodominant cd4 + t lymphocyte epitopes that elicit variant-spec..
a common mucosal chemokine (mucosae-associated epithelial chemokine/ccl28) selectively attracts iga plasmablasts
tumor-derived tgf- reduces the efficacy of dendritic cell/tumor fusion vaccine
a role for triggering receptor expressed on myeloid cells-1 in host defense during the early-induced and adaptive phases of the immune response
the resolution of relapsing fever borreliosis requires igm and is concurrent with expansion of b1b lymphocytes
differential -herpesvirus distribution in distinct anatomical locations and cell subsets during persistent infection in mice
il-4 exacerbates anaphylaxis
unique regulation of ccl18 production by maturing dendritic cells
the extracellular matrix and cytokines regulate microglial integrin expression and activation
stat4 signal pathways regulate inflammation and airway physiology changes in allergic airway inflammation locally via alteration of chemokines
modulation of cutaneous inflammation by angiotensin-converting enzyme
sodium phenylacetate inhibits adoptive transfer of experimental allergic encephalomyelitis in sjl/j mice at multiple steps
complement factor c5a mediates renal ischemia-reperfusion injury independent from neutrophils
ifn- induces high mobility group box 1 protein release partly through a tnf-dependent mechanism
intranasal immunotherapy is more effective than intradermal immunotherapy for the induction of airway allergen tolerance in th2-sensitized mice
viremia control despite escape from a rapid and potent autologous neutralizing antibody response after therapy cessation in an hiv-1-infected individual
il-12 deficiency in mrl- fas lpr mice delays nephritis and intrarenal ifn- expression, and diminishes systemic pathology
cutting edge: cure of colitis by cd4 + cd25 + regulatory t cells
cd4 + t cells pass through an effector phase during the process of in vivo tolerance induction
t cell tolerance to a neo-self antigen expressed by thymic epithelial cells: the soluble form is more effective than the membrane-bound form
cross-linking of cd32 induces maturation of human monocyte-derived dendritic cells via nf- b signaling pathway
inducible t cell tyrosine kinase regulates actin-dependent cytoskeletal events induced by the t cell antigen receptor
strategic compartmentalization of toll-like receptor 4 in the mouse gut
light (a cellular ligand for herpes virus entry mediator and lymphotoxin receptor)-mediated thymocyte deletion is dependent on the interaction between tcr and mhc/s..
a fractal clonotype distribution in the cd8 + memory t cell repertoire could optimize potential for immune responses
architectural defects in the spleens of nkx2-3-deficient mice are intrinsic and associated with defects in both b cell maturation and t cell-dependent immune respon..
detection and characterization of t cells specific for bdc2.5 t cell-stimulating peptides
optimal chemotactic responses of leukemic t cells to stromal cell-derived factor-1 requires the activation of both class ia and ib phosphoinositide 3-kinases
il-1 receptor-associated kinase 4 is essential for il-18-mediated nk and th1 cell responses
soluble fibrinogen-like protein 2/fibroleukin exhibits immunosuppressive properties: suppressing t cell proliferation and inhibiting maturation of bone marrow-deriv..
regulation of activin a expression in mast cells and asthma: its effect on the proliferation of human airway smooth muscle cells
expression of the nf- b target gene x-ray-inducible immediate early response factor-1 short enhances tnf- -induced hepatocyte apoptosis by inhibiting akt activation
cpg-a-induced monocyte ifn- -inducible protein-10 production is regulated by plasmacytoid dendritic cell-derived ifn-
mature dendritic cells derived from human monocytes within 48 hours: a novel strategy for dendritic cell differentiation from blood precursors
direct visualization of cross-reactive effector and memory allo-specific cd8 t cells generated in response to viral infections
distinct requirements for il-7 in development of tcr cells during fetal and adult life
the gp49b1 inhibitory receptor regulates the ifn- responses of t cells and nk cells
a subset of toll-like receptor ligands induces cross-presentation by bone marrow-derived dendritic cells
il-21 induces the apoptosis of resting and activated primary b cells
adenovirus e1a, not human papillomavirus e7, sensitizes tumor cells to lysis by macrophages through nitric oxide- and tnf- -dependent mechanisms despite up-regulati..
regulation of t cell activation and tolerance by phospholipase c -1-dependent integrin avidity modulation
definition of structural prerequisites for lipoteichoic acid-inducible cytokine induction by synthetic derivatives
communication between nf- b and sp1 controls histone acetylation within the proximal promoter of the monocyte chemoattractant protein 1 gene
staphylococcal enterotoxin h induces v -specific expansion of t cells
apcs present a k -derived peptides that are autoantigenic to type b t cells
analysis of the tcr variable gene repertoire in chimpanzees: identification of functional homologs to human pseudogenes
threonine phosphorylation sites in the 2 and 7 leukocyte integrin polypeptides
regulation of mhc class i transport in human dendritic cells and the dendritic-like cell line kg-1
the fcr subunit and syk kinase replace the cd3 -chain and zap-70 kinase in the tcr signaling complex of human effector cd4 t cells
intracellular retention of the mhc class i-related chain b ligand of nkg2d by the human cytomegalovirus ul16 glycoprotein
host absence of ccr5 potentiates dendritic cell vaccination
hyperoxia mediates acute lung injury and increased lethality in murine legionella pneumonia: the role of apoptosis
coxiella burnetii avoids macrophage phagocytosis by interfering with spatial distribution of complement receptor 3
modulation of human -defensin-2 transcription in pulmonary epithelial cells by lipopolysaccharide-stimulated mononuclear phagocytes via proinflammatory cytokine pro..
genetically resistant mice lacking myd88-adapter protein display a high susceptibility to leishmania major infection associated with a polarized th2 response
a chimeric multi-human epidermal growth factor receptor-2 b cell epitope peptide vaccine mediates superior antitumor responses
tcr v 8 + t cells prevent development of toxoplasmic encephalitis in balb/c mice genetically resistant to the disease
decreased stimulation of cd4 + t cell proliferation and il-2 production by highly enriched populations of hiv-infected dendritic cells
persistence of lesions in suppressor of cytokine signaling-1-deficient mice infected with leishmania major
identification and characterization of the immunodominant rat her-2/neu mhc class i epitope presented by spontaneous mammary tumors from her-2/neu-transgenic mice
a replication competent adenovirus 5 host range mutant-simian immunodeficiency virus (siv) recombinant priming/subunit protein boosting vaccine regimen induces broa..
up-regulation of cysteinyl leukotriene 1 receptor by il-13 enables human lung fibroblasts to respond to leukotriene c 4 and produce eotaxin
proteinase-activated receptor-2-induced colonic inflammation in mice: possible involvement of afferent neurons, nitric oxide, and paracellular permeability
transient neutrophil infiltration after allergen challenge is dependent on specific antibodies and fc iii receptors
a peptide derived from the parasite receptor, complement c2 receptor inhibitor trispanning, suppresses immune complex-mediated inflammation in mice
essential role of fc receptors in anti-type ii collagen antibody-induced arthritis
l-selectin or icam-1 deficiency reduces an immediate-type hypersensitivity response by preventing mast cell recruitment in repeated elicitation of contact hypersens..
neutrophil restraint by green tea: inhibition of inflammation, associated angiogenesis, and pulmonary fibrosis
frequencies of circulating cytolytic, cd45ra + cd27 -, cd8 + t lymphocytes depend on infection with cmv
direct phenotypic analysis of human mhc class i antigen presentation: visualization, quantitation, and in situ detection of human viral epitopes using peptide-speci..
human t cells express a functional ionotropic glutamate receptor glur3, and glutamate by itself triggers integrin-mediated adhesion to laminin and fibronectin and c..
development of peptide mimotopes of lipooligosaccharide from nontypeable haemophilus influenzae as vaccine candidates
t cell immunity to herpes simplex viruses in seronegative subjects: silent infection or acquired immunity?
b7-1 costimulatory molecule is critical for the development of experimental autoimmune myasthenia gravis
t cell costimulus-independent and very efficacious inhibition of tumor growth in mice bearing subcutaneous or leukemic human b cell lymphoma xenografts by a cd19-/c..
hiv-specific cd8 + t cell function in children with vertically acquired hiv-1 infection is critically influenced by age and the state of the cd4 + t cell compartment
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