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免疫学杂志2003年第03期封面 购买


cutting edge: molecular cloning of a killer cell ig-like receptor in the mouse and rat
cutting edge: dysfunctional cd8 + t cells reside in nonlymphoid tissues during chronic trypanosoma cruzi infection
cutting edge: histamine inhibits ifn- release from plasmacytoid dendritic cells
cutting edge: mast cell antimicrobial activity is mediated by expression of cathelicidin antimicrobial peptide
cutting edge: scavenging of inflammatory cc chemokines by the promiscuous putatively silent chemokine receptor d6
combined autoimmune models of arthritis reveal shared and independent qualitative (binary) and quantitative trait loci
the yaa mutation promoting murine lupus causes defective development of marginal zone b cells
a role for class a scavenger receptor in dendritic cell nibbling from live cells
inducible costimulatory molecule-b7-related protein 1 interactions are important for the clonal expansion and b cell helper functions of naive, th1, and th2 t cells
induction of low dose oral tolerance in monocyte chemoattractant protein-1- and ccr2-deficient mice
heterogeneity of dendritic cells in the mouse liver: identification and characterization of four distinct populations
expression of complement 3 and complement 5 in newt limb and lens regeneration 1,
human heat shock protein 60 induces maturation of dendritic cells versus a th1-promoting phenotype
cd7 is a differentiation marker that identifies multiple cd8 t cell effector subsets
growth factor independence-1b expression leads to defects in t cell activation, il-7 receptor expression, and t cell lineage commitment
oligodeoxynucleotides without cpg motifs work as adjuvant for the induction of th2 differentiation in a sequence-independent manner
polycyclic aromatic hydrocarbons inhibit differentiation of human monocytes into macrophages
primary and secondary immunocompetence in mixed allogeneic chimeras
human invariant v 24-j q tcr supports the development of cd1d-dependent nk1.1 + and nk1.1 - t cells in transgenic mice
memory cd8 + t cells provide an early source of ifn-
the 19-kda mycobacterium tuberculosis protein induces macrophage apoptosis through toll-like receptor-2
batf transgenic mice reveal a role for activator protein-1 in nkt cell development
role of tcr-induced extracellular signal-regulated kinase activation in the regulation of early il-4 expression in naive cd4 + t cells
inhibition of th2 differentiation and gata-3 expression by bcl-6
distinct thresholds for cd8 t cell activation lead to functional heterogeneity: cd8 t cell priming can occur independently of cell division
hiv envelope induces virus expression from resting cd4 + t cells isolated from hiv-infected individuals in the absence of markers of cellular activation or apoptosis
inhibition of tcr-induced cd8 t cell death by il-12: regulation of fas ligand and cellular flip expression and caspase activation by il-12
immediate early effector functions of virus-specific cd8 + ccr7 + memory cells in humans defined by hla and cc chemokine ligand 19 tetramers
glucocorticoid-induced apoptosis of thymocytes: requirement of proteasome-dependent mitochondrial activity
turnover rates of b cells, t cells, and nk cells in simian immunodeficiency virus-infected and uninfected rhesus macaques
il-13 is necessary, not simply sufficient, for epicutaneously induced th2 responses to soluble protein antigen
long-term maintenance of gp120-specific immune responses by genetic vaccination with the hiv-1 envelope genes linked to the gene encoding flt-3 ligand
regulatory cd8 + t cells control neonatal tolerance to a th2-mediated autoimmunity
cd4 + cd25 - t cells that express latency-associated peptide on the surface suppress cd4 + cd45rb high -induced colitis by a tgf- -dependent mechanism
selective induction of high avidity ctl by altering the balance of signals from apc
role of the polymeric ig receptor in mucosal b cell homeostasis
nkt cells provide help for dendritic cell-dependent priming of mhc class i-restricted cd8 + t cells in vivo
unique monoclonal antibodies define expression of fc ri on macrophages and mast cell lines and demonstrate heterogeneity among subcutaneous and other dendritic cells
bone morphogenetic protein-7 inhibits constitutive and interleukin-1 -induced monocyte chemoattractant protein-1 expression in human mesangial cells: role for jnk/a..
c/ebp and ets protein family members regulate the human myeloid iga fc receptor ( fc r, cd89 ) promoter
the t cell receptor locus of the channel catfish, ictalurus punctatus, reveals unique features
cd8-independent tumor cell recognition is a property of the t cell receptor and not the t cell
differential kinetics and specificity of ebv-specific cd4 + and cd8 + t cells during primary infection
prime boost vaccination strategies: cd8 t cell numbers, protection, and th1 bias
reduced ctl response and increased viral burden in substance p receptor-deficient mice infected with murine -herpesvirus 68
activation of tgf- by leishmania chagasi : importance for parasite survival in macrophages
severe impairment in early host defense against listeria monocytogenes in mice deficient in acid sphingomyelinase
hiv-1 tat-mediated apoptosis in human brain microvascular endothelial cells
up-regulation of proteinase-activated receptor 1 expression in astrocytes during hiv encephalitis
essential role of phosphoinositide 3-kinase in neutrophil directional movement
il-17 promotes bone erosion in murine collagen-induced arthritis through loss of the receptor activator of nf- b ligand/osteoprotegerin balance
activation of peroxisome proliferator-activated receptors in human airway smooth muscle cells has a superior anti-inflammatory profile to corticosteroids: relevance..
divergence of mechanisms regulating respiratory burst in blood and sputum eosinophils and neutrophils from atopic subjects
synthesis and secretion of monocyte chemotactic protein-1 stimulated by the high affinity receptor for ige
lipoxin a 4 and aspirin-triggered 15-epi-lipoxin a 4 inhibit human neutrophil migration: comparisons between synthetic 15 epimers in chemotaxis and transmigration w..
anti-idiotype x anti-lfa-1 bispecific antibodies inhibit metastasis of b cell lymphoma
high expression of fas ligand by synovial fluid-derived t cells in lyme arthritis
t cell repertoire development in humans with scid after nonablative allogeneic marrow transplantation
celiac disease association with cd8 + t cell responses: identification of a novel gliadin-derived hla-a2-restricted epitope
synergistic anti-tumor responses after administration of agonistic antibodies to cd40 and il-2: coordination of dendritic and cd8 + cell responses
concomitant induction of cd4 + and cd8 + t cell responses in volunteers immunized with salmonella enterica serovar typhi strain cvd 908-htra
paralytic autoimmune myositis develops in nonobese diabetic mice made th1 cytokine-deficient by expression of an ifn- receptor -chain transgene
t cell-activated macrophages are capable of both recognition and rejection of pancreatic islet xenografts
host response to malaria during pregnancy: placental monocyte recruitment is associated with elevated chemokine expression
fine-scale mapping at igad1 and genome-wide genetic linkage analysis implicate hla-dq/dr as a major susceptibility locus in selective iga deficiency and common vari..
cutting edge: impairment of dendritic cells and adaptive immunity by ebola and lassa viruses
cutting edge: toll-like receptor 9 expression is not required for cpg dna-aided cross-presentation of dna-conjugated antigens but essential for cross-priming of cd8..
cutting edge: cd40 engagement eliminates the need for brutons tyrosine kinase in b cell receptor signaling for nf- b
cutting edge: mycobacterium tuberculosis blocks ca 2+ signaling and phagosome maturation in human macrophages via specific inhibition of sphingosine kinase
endogenous dendritic cells are required for amplification of t cell responses induced by dendritic cell vaccines in vivo
unresponsiveness to lymphoid-mediated signals at the neonatal follicular dendritic cell precursor level contributes to delayed germinal center induction and limitat..
il-1 receptor-associated kinase 1 regulates susceptibility to organ-specific autoimmunity
conditional expression of murine flt3 ligand leads to expansion of multiple dendritic cell subsets in peripheral blood and tissues of transgenic mice
low activation threshold as a mechanism for ligand-independent signaling in pre-t cells
the size of the synaptic cleft and distinct distributions of filamentous actin, ezrin, cd43, and cd45 at activating and inhibitory human nk cell immune synapses 1,
forced expression of the fc receptor -chain renders human t cells hyperresponsive to tcr/cd3 stimulation
t cell activation in vivo targets diacylglycerol kinase to the membrane: a novel mechanism for ras attenuation
detection of suppressor t lymphocytes and estimation of their frequency in limiting dilution assays by generalized linear regression modeling
vav-1 and the ikk subunit of i b kinase functionally associate to induce nf- b activation in response to cd28 engagement
role of the cytoplasmic tails of cxcr1 and cxcr2 in mediating leukocyte migration, activation, and regulation
provision of 4-1bb ligand enhances effector and memory ctl responses generated by immunization with dendritic cells expressing a human tumor-associated antigen
acute alcohol inhibits tnf- processing in human monocytes by inhibiting tnf/tnf- -converting enzyme interactions in the cell membrane
glucocorticoids alter the lipid and protein composition of membrane rafts of a murine t cell hybridoma
a pool of central memory-like cd4 t cells contains effector memory precursors
the role of the cd134-cd134 ligand costimulatory pathway in alloimmune responses in vivo
protein kinase a regulates gata-3-dependent activation of il-5 gene expression in th2 cells
secretion of il-2 and ifn-, but not il-4, by antigen-specific t cells requires extracellular atp
the cyclic adenosine 5‘-monophosphate response element modulator suppresses il-2 production in stimulated t cells by a chromatin-dependent mechanism
quantifying recruitment of cytosolic peptides for hla class i presentation: impact of tap transport
regulatory t cells control autoimmunity in vivo by inducing apoptotic depletion of activated pathogenic lymphocytes
cu/zn superoxide dismutase plays important role in immune response
cd28 signal enhances apoptosis of cd8 t cells after strong tcr ligation
a threshold for central t cell tolerance to an inducible serum protein
blockade of cd40-mediated signaling is sufficient for inducing islet but not skin transplantation tolerance
activation of alloreactive cd8 + t cells operates via cd4-dependent and cd4-independent mechanisms and is cd154 blockade sensitive
ca 2+ stores and ca 2+ entry differentially contribute to the release of il-1 and il-1 from murine macrophages
mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo
elimination of leukemia in the absence of lethal graft-versus-host disease after allogenic bone marrow transplantation
ige-mediated activation of nk cells through fc riii
the roles of toll-like receptor 9, myd88, and dna-dependent protein kinase catalytic subunit in the effects of two distinct cpg dnas on dendritic cell subsets
proline-rich tyrosine kinase 2 and rac activation by chemokine and integrin receptors controls nk cell transendothelial migration
differential distribution of hla-dq /dr epitopes in the two forms of guillain-barré syndrome, acute motor axonal neuropathy and acute inflammatory demyelinating po..
the four tcr genes of teleost fish: the cdna and genomic dna analysis of japanese flounder ( paralichthys olivaceus ) tcr -, -, -, and -chains
ikaros isoform x is selectively expressed in myeloid differentiation
cd40-mediated transcriptional regulation of the il-6 gene in b lymphocytes: involvement of nf- b, ap-1, and c/ebp
role of nfatx (nfat4/nfatc3) in expression of immunoregulatory genes in murine peripheral cd4 + t cells
nf- b is required for surface ig-induced fas resistance in b cells
identification of a functionally impaired positive regulatory domain i binding factor 1 transcription repressor in myeloma cell lines
human igg2 can form covalent dimers
inhibition of nf- b activity in t and nk cells results in defective effector cell expansion and production of ifn- required for resistance to toxoplasma gondii
role of cd1d in coxsackievirus b3-induced myocarditis
human nkt cells express granulysin and exhibit antimycobacterial activity
immunogene therapy of tumors with vaccine based on xenogeneic epidermal growth factor receptor
dendritic cell (dc)-based protection against an intracellular pathogen is dependent upon dc-derived il-12 and can be induced by molecularly defined antigens
cd40 ligand trimer enhances the response of cd8 + t cells to mycobacterium tuberculosis
cd4 + t cell-induced differentiation of ebv-transformed lymphoblastoid cells is associated with diminished recognition by ebv-specific cd8 + cytotoxic t cells
the dendritic cell-specific chemokine, dendritic cell-derived cc chemokine 1, enhances protective cell-mediated immunity to murine malaria
perforin-mediated effector function within the central nervous system requires ifn- -mediated mhc up-regulation
serum-resistant strains of borrelia burgdorferi evade complement-mediated killing by expressing a cd59-like complement inhibitory molecule
lupus-prone mice have an abnormal response to thioglycolate and an impaired clearance of apoptotic cells
proinflammatory activities of s100: proteins s100a8, s100a9, and s100a8/a9 induce neutrophil chemotaxis and adhesion
pre-existing glomerular immune complexes induce polymorphonuclear cell recruitment through an fc receptor-dependent respiratory burst: potential role in the perpetu..
reduced macrophage recruitment, proliferation, and activation in colony-stimulating factor-1-deficient mice results in decreased tubular apoptosis during renal infl..
activation of stat3 by il-6 and il-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3
monocytes are potent facilitators of alveolar neutrophil emigration during lung inflammation: role of the ccl2-ccr2 axis
secretory phospholipases a 2 activate selective functions in human eosinophils
engineered recombinant peanut protein and heat-killed listeria monocytogenes coadministration protects against peanut-induced anaphylaxis in a murine model
a causative relationship exists between eosinophils and the development of allergic pulmonary pathologies in the mouse
il-4 down-regulates anaphylatoxin receptors in monocytes and dendritic cells and impairs anaphylatoxin-induced migration in vivo
ifn- reverses the stop signal allowing migration of antigen-specific t cells into inflammatory sites
redundancy of a functional melanocortin 1 receptor in the anti-inflammatory actions of melanocortin peptides: studies in the recessive yellow (e/e) mouse suggest an..
neutrophils promote mononuclear cell infiltration during viral-induced encephalitis
the cytokine macrophage migration inhibitory factor reduces pro-oxidative stress-induced apoptosis
cxcr2 regulates respiratory syncytial virus-induced airway hyperreactivity and mucus overproduction
down-regulation of proinflammatory capacity during apoptosis in human polymorphonuclear leukocytes
il-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis
macrophage metalloelastase as a major factor for glomerular injury in anti-glomerular basement membrane nephritis
a broad-spectrum caspase inhibitor attenuates allergic airway inflammation in murine asthma model
role of the chemokine stromal cell-derived factor 1 in autoantibody production and nephritis in murine lupus
ctla-4 blockade enhances the therapeutic effect of an attenuated poxvirus vaccine targeting p53 in an established murine tumor model
prothrombin binds to the surface of apoptotic, but not viable, cells and serves as a target of lupus anticoagulant autoantibodies
cytokine polymorphisms play a role in susceptibility to ultraviolet b-induced modulation of immune responses after hepatitis b vaccination
accumulation of b lymphocytes with a naive, resting phenotype in a subset of hepatitis c patients
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