cutting edge: identification of the targets of clonal deletion in an unmanipulated thymus
il-10 modulates host responses and lung damage induced by pneumocystis carinii infection
autocrine type i ifn and contact with endothelium promote the presentation of influenza a virus by monocyte-derived apc
novel quantitative trait loci controlling development of experimental autoimmune encephalomyelitis and proportion of lymphocyte subpopulations
acceleration of human neutrophil apoptosis by trail
role of vesicle-associated membrane protein-2, through q-soluble n -ethylmaleimide-sensitive factor attachment protein receptor/r-soluble n -ethylmaleimide-sensitiv..
cyclooxygenase-2 expression by nonsteroidal anti-inflammatory drugs in human airway smooth muscle cells: role of peroxisome proliferator-activated receptors
cpg dna induces self and cross-hyporesponsiveness of raw264.7 cells in response to cpg dna and lipopolysaccharide: alterations in il-1 receptor-associated kinase ex..
new loci regulating rat myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis
innate immunity mediated by the cytokine il-1 homologue 4 (il-1h4/il-1f7) induces il-12-dependent adaptive and profound antitumor immunity
regulation of cyclooxygenase-2 expression by macrophages in response to double-stranded rna and viral infection
enhanced th2 cell-mediated allergic inflammation in tyk2-deficient mice
chemoattraction of human t cells by il-18
selective i b kinase expression in airway epithelium generates neutrophilic lung inflammation
cd8 t cells are not essential to the pathogenesis of arthritis or colitis in hla-b27 transgenic rats
diverse repertoire of hiv-1 p24-specific, ifn- -producing cd4 + t cell clones following immune reconstitution on highly active antiretroviral therapy
interaction of the estrogen receptors with the fas ligand promoter in human monocytes
detection of low-avidity cd4 + t cells using recombinant artificial apc: following the antiovalbumin immune response
a novel polymorphic caat/enhancer-binding protein element in the fasl gene promoter alters fas ligand expression: a candidate background gene in african american sy..
prostaglandins inhibit 5-lipoxygenase-activating protein expression and leukotriene b 4 production from dendritic cells via an il-10-dependent mechanism
cutting edge: bacterial lipoprotein induces endotoxin-independent tolerance to septic shock
induction of telomerase activity and maintenance of telomere length in virus-specific effector and memory cd8 + t cells
human -t lymphocytes express and synthesize connective tissue growth factor: effect of il-15 and tgf- 1 and comparison with -t lymphocytes
critical paracrine interactions between tnf- and il-10 regulate lipopolysaccharide-stimulated human choriodecidual cytokine and prostaglandin e 2 production
differential expression of platelet-activating factor acetylhydrolase in macrophages and monocyte-derived dendritic cells
high avidity cd8 + t cells are the initial population elicited following viral infection of the respiratory tract
models for antigen receptor gene rearrangement. iii. heavy and light chain allelic exclusion
cutting edge: induced expression of a rhoa-specific guanine nucleotide exchange factor, p190rhogef, following cd40 stimulation and wehi 231 b cell activation
toll-like receptor 2 ligands as adjuvants for human th1 responses
self-specific mhc class ii-restricted cd4 - cd8 - t cells that escape deletion and lack regulatory activity
a role for stat5 in cd8 + t cell homeostasis
regulation of mouse mammary tumor virus env transcriptional activator initiated mammary tumor virus superantigen transcripts in lymphomas of sjl/j mice: role of ika..
in vivo augmentation of tumor-specific ctl responses by class i/peptide antigen complexes on microspheres (large multivalent immunogen)
efficient induction of primary and secondary t cell-dependent immune responses in vivo in the absence of functional il-2 and il-15 receptors
cutting edge: dissociation between autoimmune response and clinical disease after vaccination with dendritic cells
a gammaherpesvirus g protein-coupled receptor homologue is required for increased viral replication in response to chemokines and efficient reactivation from latenc..
pre-b cell antigen receptor-mediated signal inhibits cd24-induced apoptosis in human pre-b cells
a division-linked mechanism for the rapid generation of ig-secreting cells from human memory b cells
il-4-induced arginase 1 suppresses alloreactive t cells in tumor-bearing mice
cd25 + immunoregulatory cd4 t cells mediate acquired central transplantation tolerance
cutting edge: l-selectin (cd62l) expression distinguishes small resting memory cd4 + t cells that preferentially respond to recall antigen
inhibition of calpain is a component of nitric oxide-induced down-regulation of human mast cell adhesion
coexpression of cd58 or cd48 with intercellular adhesion molecule 1 on target cells enhances adhesion of resting nk cells
activated stat4 and a functional role for il-12 in human peyers patches
roles of vasoactive intestinal peptide (vip) in the expression of different immune phenotypes by wild-type mice and t cell-targeted type ii vip receptor transgenic ..
induction of the early growth response gene 1 promoter by tcr agonists and partial agonists: ligand potency is related to sustained phosphorylation of extracellular..
minimal requirement of tyrosine residues of linker for activation of t cells in tcr signaling and thymocyte development
expression of the murine cd27 ligand cd70 in vitro and in vivo
regulation of cell type-specific mouse fc ri -chain gene expression by gata-1 via four gata motifs in the promoter
fibroblast growth factor-inducible 14 mediates multiple pathways of tweak-induced cell death
expression of the grb2-related protein of the lymphoid system in b cell subsets enhances b cell antigen receptor signaling through mitogen-activated protein kinase ..
serial analysis of gene expression in circulating t cell subsets defines distinct immunoregulatory phenotypes and unexpected gene expression profiles
src homology 2 domain-containing leukocyte phosphoprotein of 76 kda and phospholipase c 1 are required for nf- b activation and lipid raft recruitment of protein ki..
high affinity xenoreactive tcr:mhc interaction recruits cd8 in absence of binding to mhc
the role of ox40 ligand interactions in the development of the th2 response to the gastrointestinal nematode parasite heligmosomoides polygyrus 1,
cd4 + cd25 + regulatory t cells suppress differentiation and functions of th1 and th2 cells, leishmania major infection, and colitis in mice
human cd4 + t cells present within the microenvironment of human lung tumors are mobilized by the local and sustained release of il-12 to kill tumors in situ by ind..
guanine exchange-dependent and -independent effects of vav1 on integrin-induced t cell spreading 1,
identification of mouse md-2 residues important for forming the cell surface tlr4-md-2 complex recognized by anti-tlr4-md-2 antibodies, and for conferring lps and t..
transgenic expression of stromal cell-derived factor-1/cxc chemokine ligand 12 enhances myeloid progenitor cell survival/antiapoptosis in vitro in response to growt..
survival of mycobacterium tuberculosis in host macrophages involves resistance to apoptosis dependent upon induction of antiapoptotic bcl-2 family member mcl-1
toll-like receptor 2 participates in mediation of immune response in experimental pneumococcal meningitis
proteomics and immunological analysis of a novel shrimp allergen, pen m 2
chimeras of labile toxin one and cholera toxin retain mucosal adjuvanticity and direct th cell subsets via their b subunit
characterization of lung t cells following intranasal infection with mycobacterium bovis bacillus calmette-guérin
lack of c3 affects th2 response development and the sequelae of chemotherapy in schistosomiasis
ablation of cd8 and cd4 t cell responses by high viral loads
recognition of a specific self-peptide: self-mhc class ii complex is critical for positive selection of thymocytes expressing the d10 tcr
identification of heat shock protein 60 as the ligand on histoplasma capsulatum that mediates binding to cd18 receptors on human macrophages
hiv mucosal vaccine: nasal immunization with gp160-encapsulated hemagglutinating virus of japan-liposome induces antigen-specific ctls and neutralizing antibody res..
cutting edge: targeting of v to d rearrangement by rsss can be mediated by the v(d)j recombinase in the absence of additional lymphoid-specific factors
protective effects of il-6 blockade in sepsis are linked to reduced c5a receptor expression
induction of in vitro reprogramming by toll-like receptor (tlr)2 and tlr4 agonists in murine macrophages: effects of tlr “homotolerance“ versus “heterotolerance..
critical role of the 4 integrin/vcam-1 pathway in cerebral leukocyte trafficking in lupus-prone mrl/ fas lpr mice
house dust mite dermatophagoides farinae augments proinflammatory mediator productions and accessory function of alveolar macrophages: implications for allergic sen..
the ccr3 receptor is involved in eosinophil differentiation and is up-regulated by th2 cytokines in cd34 + progenitor cells
oncostatin m regulates eotaxin expression in fibroblasts and eosinophilic inflammation in c57bl/6 mice
strong differential regulation of serum and mucosal iga responses as revealed in cd28-deficient mice using cholera toxin adjuvant
oxidant-mediated mitochondrial injury in eosinophil apoptosis: enhancement by glucocorticoids and inhibition by granulocyte-macrophage colony-stimulating factor
repression of bleomycin-induced pneumopathy by tnf
by il-1 signaling, monocyte-derived cells dramatically enhance the epidermal antimicrobial response to lipopolysaccharide
ccr8 is not essential for the development of inflammation in a mouse model of allergic airway disease
antagonist of secondary lymphoid-tissue chemokine (ccr ligand 21) prevents the development of chronic graft-versus-host disease in mice
impaired accumulation and function of memory cd4 t cells in human il-12 receptor 1 deficiency
absence of il-4 facilitates the development of chronic autoimmune myasthenia gravis in c57bl/6 mice
il-4-producing cd8 + t cells with a cd62l ++( bright ) phenotype accumulate in a subgroup of older adults and are associated with the maintenance of intact humoral ..
impaired processing and presentation by mhc class ii proteins in human diabetic cells
autoimmune encephalomyelitis and uveitis induced by t cell immunity to self -synuclein
dichotomy of autoreactive th1 and th2 cell responses to desmoglein 3 in patients with pemphigus vulgaris (pv) and healthy carriers of pv-associated hla class ii all..
intracellular calcium waves accompany neutrophil polarization, formylmethionylleucylphenylalanine stimulation, and phagocytosis: a high speed microscopy study
cutting edge: proliferating fibroblasts respond to collagenous c1q with phosphorylation of p38 mitogen-activated protein kinase and apoptotic features
cutting edge: homeostatic proliferation of peripheral t lymphocytes is regulated by clonal competition
inhibition of metalloproteinase cleavage enhances the cytotoxicity of fas ligand
intrinsic differences in the proliferation of naive and memory human b cells as a mechanism for enhanced secondary immune responses
hypoxia regulates expression and activity of kv1.3 channels in t lymphocytes: a possible role in t cell proliferation
impaired lymphopoiesis and altered b cell subpopulations in mice overexpressing lnk adaptor protein
program death-1 engagement upon tcr activation has distinct effects on costimulation and cytokine-driven proliferation: attenuation of icos, il-4, and il-21, but no..
decreased e12 and/or e47 transcription factor activity in the bone marrow as well as in the spleen of aged mice
cd154 plays a central role in regulating dendritic cell activation during infections that induce th1 or th2 responses
cd19 function in early and late b cell development: i. maintenance of follicular and marginal zone b cells requires cd19-dependent survival signals
either il-2 or il-12 is sufficient to direct th1 differentiation by nonobese diabetic t cells
cd4 + t cells from lupus-prone mice avoid antigen-specific tolerance induction in vivo
down-modulation of responses to type i ifn upon t cell activation
mechanisms of enhanced macrophage-mediated prostaglandin e 2 production and its suppressive role in th1 activation in th2-dominant balb/c mice
protection against experimental autoimmune encephalomyelitis generated by a recombinant adenovirus vector expressing the v 8.2 tcr is disrupted by coadministration ..
long term maintenance of ige-mediated memory in mast cells in the absence of detectable serum ige
differential requirements for expression of cd80/86 and cd40 on b cells for t-dependent antibody responses in vivo
complement component 3 is required for optimal expansion of cd8 t cells during a systemic viral infection
endotoxin/lipopolysaccharide activates nf- b and enhances tumor cell adhesion and invasion through a 1 integrin-dependent mechanism
the intracellular granzyme b inhibitor, proteinase inhibitor 9, is up-regulated during accessory cell maturation and effector cell degranulation, and its overexpres..
microbial colonization drives lymphocyte accumulation and differentiation in the follicle-associated epithelium of peyers patches
indoleamine 2,3-dioxygenase is regulated by ifn- in the mouse placenta during listeria monocytogenes infection
nonmyelin-specific t cells accelerate development of central nervous system apc and increase susceptibility to experimental autoimmune encephalomyelitis
il-6 and matrix metalloproteinase-1 are regulated by the cyclin-dependent kinase inhibitor p21 in synovial fibroblasts
impaired antibody response to group b streptococcal type iii capsular polysaccharide in c3- and complement receptor 2-deficient mice
a critical role for syk protein tyrosine kinase in fc receptor-mediated antigen presentation and induction of dendritic cell maturation
ifn- production is specifically regulated by il-10 in mice made tolerant with anti-cd40 ligand antibody and intact active bone
a thyroid tumor-specific antigen formed by the fusion of two self proteins
detection of autoreactive myelin proteolipid protein 139-151-specific t cells by using mhc ii (ia s ) tetramers
suppressor of cytokine signaling-1 has ifn- -independent actions in t cell homeostasis
il-4 induces apoptosis in a549 lung adenocarcinoma cells: evidence for the pivotal role of 15-hydroxyeicosatetraenoic acid binding to activated peroxisome prolifera..
t cell chemokine receptor expression in aging
lipid raft-independent b cell receptor-mediated antigen internalization and intracellular trafficking
established t cell-driven germinal center b cell proliferation is independent of cd28 signaling but is tightly regulated through ctla-4
lipid raft distribution of cd4 depends on its palmitoylation and association with lck, and evidence for cd4-induced lipid raft aggregation as an additional mechanis..
the gtp-binding domain of class ii transactivator regulates its nuclear export
up-regulation of early growth response gene-1 via the cxcr3 receptor induces reactive oxygen species and inhibits na + /k + -atpase activity in an immortalized huma..
impaired transporter associated with antigen processing (tap) function attributable to a single amino acid alteration in the peptide tap subunit tap1
systematic analysis of the combinatorial nature of epitopes recognized by tcr leads to identification of mimicry epitopes for glutamic acid decarboxylase 65-specifi..
a single polymorphic residue within the peptide-binding cleft of mhc class i molecules determines spectrum of tapasin dependence
the gdp exchange factor and-34 is expressed in b cells, associates with hef1, and activates cdc42
a complex containing polypyrimidine tract-binding protein is involved in regulating the stability of cd40 ligand (cd154) mrna
targeting with bovine cd154 enhances humoral immune responses induced by a dna vaccine in sheep
ox40 ligand-transduced tumor cell vaccine synergizes with gm-csf and requires cd40-apc signaling to boost the host t cell antitumor response
identification of ifn regulatory factor-1 binding site in il-12 p40 gene promoter