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《核酸研究医学期刊》2004年第04期

chemical and biochemical strategies for the randomization of protein encoding dna sequences: library construction methods for directed evolution
in vivo interactions of the acanthamoeba tbp gene promoter
evidence for a subpopulation of conserved alternative splicing events under selection pressure for protein reading frame preservation
hiv-1 tat directly binds to nfb enhancer sequence: role in viral and cellular gene expression
roles of auf1 isoforms, hur and brf1 in are-dependent mrna turnover studied by rna interference
dna elements important for cag?ctg repeat thresholds in saccharomyces cerevisiae
leon: multiple alignment evaluation of neighbours
identification of cellular proteins enhancing activities of internal ribosomal entry sites by competition with oligodeoxynucleotides
transcriptional regulation of the drosophila catalase gene by the dre/dref system
the active form of xp54 rna helicase in translational repression is an rna-mediated oligomer
the helix
the dna-binding properties of the arid-containing subunits of yeast and mammalian swi/snf complexes
ctcf-dependent enhancer blockers at the upstream region of the chicken -globin gene domain
arb: a software environment for sequence data
detection of functional dna motifs via statistical over-representation
5'-untranslated regions with multiple upstream aug codons can support low-level translation via leaky scanning and reinitiation
paradigms for computational nucleic acid design
identifying secretomes in people, pufferfish and pigs
conformational change of pseudouridine 55 synthase upon its association with rna substrate
uv-c response of the ribonucleotide reductase large subunit involves both e2f-mediated gene transcriptional regulation and protein subcellular relocalization in tob..
a bipolar dna helicase gene, hera, clusters with rad50, mre11 and nura genes in thermophilic archaea
pkd1 intron 21: triplex dna formation and effect on replication
efficient rna interference depends on global context of the target sequence: quantitative analysis of silencing efficiency using eulerian graph representation of si..
the involvement of srs2 in post-replication repair and homologous recombination in fission yeast
ring1 inhibits transactivation of rbp-j by notch through interaction with lim protein kyot2
two-hybrid mpp10p interaction-defective imp4 proteins are not interaction defective in vivo but do confer specific pre-rrna processing defects in saccharomyces cere..
solid phase synthesis and binding affinity of peptidyl transferase transition state mimics containing 2'-oh at p-site position a76
modified u1 snrna suppresses expression of a targeted endogenous rna by inhibiting polyadenylation of the transcript
efficiency and pattern of uv pulse laser-induced rna
biochemical and random mutagenesis analysis of the region carrying the catalytic e152 amino acid of hiv-1 integrase
using pyrrolo-deoxycytosine to probe rna/dna hybrids containing the human immunodeficiency virus type-1 3' polypurine tract
interaction of human and bacterial alkb proteins with dna as probed through chemical cross-linking studies
integration of the 5' end of the retrotransposon, r2bm, can be complemented by homologous recombination
influence of in vitro manipulation on the stability of methylation patterns in the snurf/snrpn-imprinting region in mouse embryonic stem cells
myosin light chain 1 atrial isoform (mlc1a) is expressed in pre-b cells under control of the bob.1/obf.1 coactivator
dna dynamically directs its own transcription initiation
sequence-specific cleavage of rna in the absence of divalent metal ions by a dnazyme incorporating imidazolyl and amino functionalities
processing of clustered dna damage generates additional double-strand breaks in mammalian cells post-irradiation
a theophylline responsive riboswitch based on helix slipping controls gene expression in vivo
homologous gene targeting in caenorhabditis elegans by biolistic transformation
intensity-based analysis of two-colour microarrays enables efficient and flexible hybridization designs
straightforward detection of snps in double-stranded dna by using exonuclease iii/nuclease s1/pna system
quantitative high-throughput analysis of transcription factor binding specificities
a high-throughput method to monitor the expression of microrna precursors
identification and handling of artifactual gene expression profiles emerging in microarray hybridization experiments
snpwavetm: a flexible multiplexed snp genotyping technology
rnase h2 of saccharomyces cerevisiae is a complex of three proteins
a novel method for screening species-specific gdna probes for species identification
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