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核酸研究医学期刊2003年第09期封面 购买


poly(adp-ribose) polymerase (parp-1) has a controlling role in homologous recombination
differences in replication of a dna template containing an ethyl phosphotriester by t4 dna polymerase and escherichia coli dna polymerase i
developmental defects by antisense-mediated inactivation of micro-rnas 2 and 13 in drosophila and the identification of putative target genes
ribozyme-mediated rev1 inhibition reduces the frequency of uv-induced mutations in the human hprt gene
thermodynamic criteria for high hit rate antisense oligonucleotide design
functional conservation of dhh1p, a cytoplasmic dexd/h-box protein present in large complexes
structural motifs in the rna encoded by the early nodulation gene enod40 of soybean
elongation by rna polymerase ii on chromatin templates requires topoisomerase activity
construction and analysis of cells lacking the hmga gene family
promoter choice affects the potency of hiv-1 specific rna interference
import of mitochondrial transcription factor a (tfam) into rat liver mitochondria stimulates transcription of mitochondrial dna
enzymatic repair of an expanded genetic information system
fission yeast rhp51 is required for the maintenance of telomere structure in the absence of the ku heterodimer
nuclear factories for signalling and repairing dna double strand breaks in living fission yeast
effect of polyamines on the inhibition of peptidyltransferase by antibiotics: revisiting the mechanism of chloramphenicol action
determination of dna minor groove width in distamycin-dna complexes by solid-state nmr
analysis of the dna joining repertoire of chlorella virus dna ligase and a new crystal structure of the ligase-adenylate intermediate
mg2+-induced triplex formation of an equimolar mixture of poly(ra) and poly(ru)
3dna: a software package for the analysis, rebuilding and visualization of three-dimensional nucleic acid structures
novel chimeric immunomodulatory compounds containing short cpg oligodeoxyribonucleotides have differential activities in human cells
solution measurement of dna curvature in papillomavirus e2 binding sites
activation of site-specific dna integration in human cells by a single chain integration host factor
clerocidin alkylates dna through its epoxide function: evidence for a fine tuned mechanism of action
simultaneous gene expression analysis of steady-state and actively translated mrna populations from osteosarcoma mg-63 cells in response to il-1 via an open express..
a positively charged side chain at position 154 on the ß8-e loop of hiv-1 rt is required for stable ternary complex formation
mfp1 is a thylakoid-associated, nucleoid-binding protein with a coiled-coil structure
on the importance of the primer activation signal for initiation of trnalys3-primed reverse transcription of the hiv-1 rna genome
comparative analysis of the base biases at the gene terminal portions in seven eukaryote genomes
phosphorylation of the pcna binding domain of the large subunit of replication factor c on thr506 by cyclin-dependent kinases regulates binding to pcna
isochores and tissue-specificity
dna supercoiling enables the type iis restriction enzyme bspmi to recognise the relative orientation of two dna sequences
rad52 and ku bind to different dna structures produced early in double-strand break repair
differential regulation of the glucose-6-phosphatase tata box by intestine-specific homeodomain proteins cdx1 and cdx
the structural integrity exerted by n-terminal pyroglutamate is crucial for the cytotoxicity of frog ribonuclease from rana pipiens
light-mediated regulation defines a minimal promoter region of top
ligand-independent activation of estrogen receptor by xbp-
on the mechanism of strand assimilation by the herpes simplex virus type-1 single-strand dna-binding protein (icp8)
cationic phosphoramidate -oligonucleotides efficiently target single-stranded dna and rna and inhibit hepatitis c virus ires-mediated translation
ten members of the arabidopsis gene family encoding methyl-cpg-binding domain proteins are transcriptionally active and at least one, atmbd11, is crucial for normal..
functional dissection of the c-terminal domain of type ii dna topoisomerase from the kinetoplastid hemoflagellate leishmania donovani
retrovirus silencer blocking by the chs4 insulator is ctcf independent
complete chloroplast dna sequence of the moss physcomitrella patens: evidence for the loss and relocation of rpoa from the chloroplast to the nucleus
poly(adp-ribosyl)ation accelerates dna repair in a pathway dependent on cockayne syndrome b protein
patterns of nucleotide substitution, insertion and deletion in the human genome inferred from pseudogenes
revisiting the mouse mitochondrial dna sequence
identification of daxx interacting with p73, one of the p53 family, and its regulation of p53 activity by competitive interaction with pml
stability of the sp3-dna complex is promoter-specific: sp3 efficiently competes with sp1 for binding to promoters containing multiple sp-sites
biochemical evidence for ku-independent backup pathways of nhej
the drosophila melanogaster btb proteins bric à brac bind dna through a composite dna binding domain containing a pipsqueak and an at-hook motif
human thymine dna glycosylase (tdg) and methyl-cpg-binding protein 4 (mbd4) excise thymine glycol (tg) from a tg:g mispair
a tissue-specific knockout reveals that gata1 is not essential for sertoli cell function in the mouse
identification and characterization of a novel cross-link lesion in d(cpc) upon 365-nm irradiation in the presence of 2-methyl-1,4-naphthoquinone
dna condensation by the nucleocapsid protein of hiv-1: a mechanism ensuring dna protection
patterns in interspecies similarity correlate with nucleotide composition in mammalian 3‘utrs
crystal structure of mboiia methyltransferase
crystal structure of a wild-type cre recombinase-loxp synapse reveals a novel spacer conformation suggesting an alternative mechanism for dna cleavage activation
an enhanced u6 promoter for synthesis of short hairpin rna
improved generation of recombinant baculovirus genomes in escherichia coli
mrna fusion constructs serve in a general cell-based assay to profile oligonucleotide activity
parallel gene analysis with allele-specific padlock probes and tag microarrays
quantitation of intracellular nad(p)h can monitor an imbalance of dna single strand break repair in base excision repair deficient cells in real time
kinetic outlier detection (kod) in real-time pcr
mgview: an alignment and visualization tool to enhance gap closure of microbial genomes
rapid generation of gene disruption constructs by in vitro transposition and identification of a dictyostelium protein kinase that regulates its rate of growth and ..
studies of temperature-dependent electronic transduction on dna hairpin loop sensor
optimizing spotting solutions for increased reproducibility of cdna microarrays
an improved method for the in vitro evolution of aptamers and applications in protein detection and purification
a real-time dnase assay (reda) based on picogreen® fluorescence
conversion of sub-megasized dna to desired structures using a novel bacillus subtilis genome vector
identification of a novel proliferation-inducing determinant using lentiviral expression cloning
ligation mediated pcr performed at low denaturation temperatures-pcr melting profiles
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