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《分子药理学杂志》2008年第02期

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revoking the privilege: targeting her2 in the central nervous system
prostaglandin-induced activation of nociceptive neurons via direct interaction with transient receptor potential a1 (trpa1)
cortical glutamatergic neurons mediate the motor sedative action of diazepam
distinct phosphorylation sites in the sst2a somatostatin receptor control internalization, desensitization, and arrestin binding
conformational flexibility of helix vi is essential for substrate permeation of the human apical sodium-dependent bile acid transporter
anandamide inhibition of 5-ht3a receptors varies with receptor density and desensitization
peroxisome proliferator-activated receptor- contributes to the anti-inflammatory activity of glucocorticoids
cellular and in vivo activity of jnj-28871063, a nonquinazoline pan-erbb kinase inhibitor that crosses the blood-brain barrier and displays efficacy against intracr..
characterization of g-protein coupled receptor kinase interaction with the neurokinin-1 receptor using bioluminescence resonance energy transfer
a novel actin-binding domain on slo1 calcium-activated potassium channels is necessary for their expression in the plasma membrane
the β1 subunit of l-type voltage-gated ca2+ channels independently binds to and inhibits the gating of large-conductance ca2+-activated k+ channels
functional characterization of a nucleoside-derived drug transporter variant (hcnt3c602r) showing altered sodium-binding capacity
repression of aryl hydrocarbon receptor (ahr) signaling by ahr repressor: role of dna binding and competition for ahr nuclear translocator
curcumin protects the rat liver from ccl4-caused injury and fibrogenesis by attenuating oxidative stress and suppressing inflammation
small molecule disruption of g protein β subunit signaling inhibits neutrophil chemotaxis and inflammation
bubr1 is required for a sustained mitotic spindle checkpoint arrest in human cancer cells treated with tubulin-targeting pyrrolo-1,5-benzoxazepines
role of extracellular domain dimerization in agonist-induced activation of natriuretic peptide receptor a
inhibition of human neutrophil chemotaxis by endogenous cannabinoids and phytocannabinoids: evidence for a site distinct from cb1 and cb2
dexamethasone-mediated up-regulation of human cyp2a6 involves the glucocorticoid receptor and increased binding of hepatic nuclear factor 4 to the proximal promoter
transport of cisplatin by the copper efflux transporter atp7b
cloning and functional expression of a novel gi protein-coupled receptor for adenine from mouse brain
structural analog of sildenafil identified as a novel corrector of the f508del-cftr trafficking defect
reduced expression of dna topoisomerase i in sf295 human glioblastoma cells selected for resistance to homocamptothecin and diflomotecan
impact of targeting the adenine- and uracil-rich element of bcl-2 mrna with oligoribonucleotides on apoptosis, cell cycle, and neuronal differentiation in shsy-5y c..
a peroxisome proliferator-activated receptor -retinoid x receptor heterodimer physically interacts with the transcriptional activator pax6 to inhibit glucagon gene ..
[3h]org 43553, the first low-molecular-weight agonistic and allosteric radioligand for the human luteinizing hormone receptor
multiple binding sites for substrates and modulators of semicarbazide-sensitive amine oxidases: kinetic consequences
functional characterization of bone morphogenetic protein binding sites and smad1/5 activation in human vascular cells
methyl 2-cyano-3,11-dioxo-18β-olean-1,12-dien-30-oate is a peroxisome proliferator-activated receptor- agonist that induces receptor-independent apoptosis in lncap..
mitogenic effects of cytokines on smooth muscle are critically dependent on protein kinase a and are unmasked by steroids and cyclooxygenase inhibitors
3-methylcholanthrene displays dual effects on estrogen receptor (er) and erβ signaling in a cell-type specific fashion
regulation of lysophosphatidic acid receptor expression and function in human synoviocytes: implications for rheumatoid arthritis?
efavirenz accelerates hiv-1 reverse transcriptase ribonuclease h cleavage, leading to diminished zidovudine excision
regulation of human 3-hydroxysteroid dehydrogenase (akr1c4) expression by the liver x receptor
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