alternative translation initiation of human regulators of g-protein signaling-2 yields a set of functionally distinct proteins
conformational variations of both phosphodiesterase-5 and inhibitors provide the structural basis for the physiological effects of vardenafil and sildenafil
fp prostanoid receptor-mediated induction of the expression of early growth response factor-1 by activation of a ras/raf/mitogen-activated protein kinase signaling ..
peroxide is a key mediator of bcl-2 down-regulation and apoptosis induction by cisplatin in human lung cancer cells
a functional steroid-binding element in an atp-binding cassette multidrug transporter
induction of apoptosis by vinblastine via c-jun autoamplification and p53-independent down-regulation of p21waf1/cip1
p53 and atm/atr regulate 7,12-dimethylbenz[a]anthracene-induced immunosuppression
effect of cathepsin k inhibitor basicity on in vivo off-target activities
the investigational anticonvulsant lacosamide selectively enhances slow inactivation of voltage-gated sodium channels
enhancement of glucose transporter expression of brain endothelial cells by vascular endothelial growth factor derived from glioma exposed to hypoxia
β-arrestin-dependent µ-opioid receptor-activated extracellular signal-regulated kinases (erks) translocate to nucleus in contrast to g protein-dependent erk activ..
ahn s, shenoy sk, wei h, and lefkowitz rj (2004) differential kinetic and spatial patterns of β-arrestin and g protein-mediated erk activation by the angiotensin i..
17β-estradiol promotes breast cancer cell proliferation-inducing stromal cell-derived factor-1-mediated epidermal growth factor receptor transactivation: reversal ..
long-acting β2-adrenoceptor agonists synergistically enhance glucocorticoid-dependent transcription in human airway epithelial and smooth muscle cells
salicylate blocks lipolytic actions of tumor necrosis factor- in primary rat adipocytes
the unusual state-dependent affinity of p2x3 receptors can be explained by an allosteric two-open-state model
genistein induces phenotypic reversion of endoglin deficiency in human prostate cancer cells
disruption of camp and prostaglandin e2 transport by multidrug resistance protein 4 deficiency alters camp-mediated signaling and nociceptive response
identification of key residues coordinating functional inhibition of p2x7 receptors by zinc and copper
high mobility group protein b1 is an activator of apoptotic response to antimetabolite drugs
subcellular trafficking, pentameric assembly, and subunit stoichiometry of neuronal nicotinic acetylcholine receptors containing fluorescently labeled 6 and β3 sub..
inhibition of trpc5 channels by intracellular atp
high-affinity cation binding to organic cation transporter 1 induces movement of helix 11 and blocks transport after mutations in a modeled interaction domain betwe..
the differential interactions of peroxisome proliferator-activated receptor ligands with tyr473 is a physical basis for their unique biological activities
identification of a novel ligand binding residue arg38(1.35) in the human gonadotropin-releasing hormone receptor
inhibition of estrogen-mediated uterine gene expression responses by dioxin
constitutively active mutants of the histamine h1 receptor suggest a conserved hydrophobic asparagine-cage that constrains the activation of class a g protein-coupl..