functional selectivity through protean and biased agonism: who steers the ship?
go it alone no more—p2x7 joins the society of heteromeric atp-gated receptor channels
are 910 nicotinic acetylcholine receptors a pain target for -conotoxins?
substance p neurokinin 1 receptor activation within the dorsal raphe nucleus controls serotonin release in the mouse frontal cortex
in vivo oxidative damage in rats is associated with barbiturate response but not other cytochrome p450 inducers
myristyl trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are surface-active small molecule dynamin inhibitors that block endocytosis mediated by..
monitoring interactions between receptor tyrosine kinases and their downstream effector proteins in living cells using bioluminescence resonance energy transfer
evidence for functional p2x4/p2x7 heteromeric receptors
a dioxin-responsive enhancer 3' of the human cyp1a2 gene
mitochondria, calcium, and calpain are key mediators of resveratrol-induced apoptosis in breast cancer
transforming growth factor-1 impairs endothelin-1-mediated contraction of brain vessels by inducing mitogen-activated protein (map) kinase phosphatase-1 and inhibit..
roof and floor of the muscarinic binding pocket: variations in the binding modes of orthosteric ligands
identification of a postendocytic sorting sequence in ccr5
resveratrol (trans-3,5,4'-trihydroxystilbene) ameliorates experimental allergic encephalomyelitis, primarily via induction of apoptosis in t cells involving activat..
the molecular basis of high-affinity binding of the antiarrhythmic compound vernakalant (rsd1235) to kv1.5 channels
the n-terminal domains of both nr1 and nr2 subunits determine allosteric zn2+ inhibition and glycine affinity of n-methyl-d-aspartate receptors
docosahexaenoic acid induces increases in [ca2+]i via inositol 1,4,5-triphosphate production and activates protein kinase c and - via phosphatidylserine binding sit..
cb1 cannabinoid receptor activity is modulated by the cannabinoid receptor interacting protein crip 1a
identification of the substrate binding region of vesicular monoamine transporter-2 (vmat-2) using iodoaminoflisopolol as a novel photoprobe
inhibition of trpp3 channel by amiloride and analogs
aspirin enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in hormone-refractory prostate cancer cells through survivin down-regula..
mitochondrial expression of the drosophila melanogaster multisubstrate deoxyribonucleoside kinase
decursin suppresses human androgen-independent pc3 prostate cancer cell proliferation by promoting the degradation of -catenin
k252a prevents nigral dopaminergic cell death induced by 6-hydroxydopamine through inhibition of both mixed-lineage kinase 3/c-jun nh2-terminal kinase 3 (jnk3) and ..
regulation of tissue-specific expression of the human and mouse urate transporter 1 gene by hepatocyte nuclear factor 1 / and dna methylation
adenosine a2a receptor occupancy stimulates collagen expression by hepatic stellate cells via pathways involving protein kinase a, src, and extracellular signal-reg..
cystine-glutamate transporter slc7a11 mediates resistance to geldanamycin but not to 17-(allylamino)-17-demethoxygeldanamycin
repression of t-cell function by thionamides is mediated by inhibition of the activator protein-1/nuclear factor of activated t-cells pathway and is associated with..
incensole acetate, a novel anti-inflammatory compound isolated from boswellia resin, inhibits nuclear factor-b activation