the aryl hydrocarbon receptor sans xenobiotics: endogenous function in genetic model systems
the mirp2-kv3.4 potassium channel: muscling in on alzheimer's disease
localization of the mouse 5-hydroxytryptamine1a receptor in lipid microdomains depends on its palmitoylation and is involved in receptor-mediated signaling
transcription factor binding to a putative double e-box motif represses cyp3a4 expression in human lung cells
molecular analysis of the interaction of bordetella pertussis adenylyl cyclase with fluorescent nucleotides
the impact of hypoxic treatment on the expression of phosphoglycerate kinase and the cytotoxicity of troxacitabine and gemcitabine
philinopside e, a new sulfated saponin from sea cucumber, blocks the interaction between kinase insert domain-containing receptor (kdr) and v3 integrin via binding ..
dynamin 2 regulates riboflavin endocytosis in human placental trophoblasts
structural basis of spirolactone recognition by the mineralocorticoid receptor
discovery of a highly active ligand of human pregnane x receptor: a case study from pharmacophore modeling and virtual screening to "in vivo" biological activity
substrate specificities of g protein-coupled receptor kinase-2 and -3 at cardiac myocyte receptors provide basis for distinct roles in regulation of myocardial func..
human pregnane x receptor antagonists and agonists define molecular requirements for different binding sites
the human udp-glucuronosyltransferase: identification of key residues within the nucleotide-sugar binding site
a key role for diacylglycerol lipase- in metabotropic glutamate receptor-dependent endocannabinoid mobilization
interactions with filamin a stimulate surface expression of large-conductance ca2+-activated k+ channels in the absence of direct actin binding
a new steroid derivative stabilizes g-quadruplexes and induces telomere uncapping in human tumor cells
the phosphoinositide-dependent kinase-1 inhibitor 2-amino-n-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1h-pyrazol-1-yl]phenyl]-acetamide (osu-03012) prevents y-box..
exacerbation of dopaminergic terminal damage in a mouse model of parkinson's disease by the g-protein-coupled receptor protease-activated receptor 1
up-regulation and increased activity of kv3.4 channels and their accessory subunit mink-related peptide 2 induced by amyloid peptide are involved in apoptotic neuro..
apoptotic action of peroxisome proliferator-activated receptor- activation in human non–small-cell lung cancer is mediated via proline oxidase-induced reactive oxy..
interleukin-6 alters the cellular responsiveness to clopidogrel, irinotecan, and oseltamivir by suppressing the expression of carboxylesterases hce1 and hce2
stromal cell-derived factor-1 induces matrix metalloprotease-13 expression in human chondrocytes
low-dose bbr3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of epidermal growth factor receptor (erbb1)-phosphatidyl inositol 3 ki..
distinct profiles of 7 nachr positive allosteric modulation revealed by structurally diverse chemotypes
thiazolidinediones modulate the expression of -catenin and other cell-cycle regulatory proteins by targeting the f-box proteins of skp1-cul1-f-box protein e3 ubiqui..
functional characterization of the promoter of human carbonyl reductase 1 (cbr1). role of xre elements in mediating the induction of cbr1 by ligands of the aryl hyd..
perturbation of dopamine metabolism by 3-amino-2-(4'-halophenyl)propenes leads to increased oxidative stress and apoptotic sh-sy5y cell death
phosphorylation of gs influences its association with the µ-opioid receptor and is modulated by long-term morphine exposure
nicotine glucuronidation and the human udp-glucuronosyltransferase ugt2b10
signaling pathways involved in cyclooxygenase-2 induction by hepatocyte growth factor in non–small-cell lung cancer
modulation of presynaptic 3-containing gabaa receptors limits the immobilizing actions of gabaergic anesthetics
the multikinase inhibitor sorafenib induces apoptosis in highly imatinib mesylate-resistant bcr/abl+ human leukemia cells in association with signal transducer and ..