receptor-mediated activation of heterotrimeric g-proteins: current structural insights
challenges and opportunities of trapping ligands
brain-derived neurotrophic factor: linking fear learning to memory consolidation
trapping of a nonpeptide ligand by the extracellular domains of the gonadotropin-releasing hormone receptor results in insurmountable antagonism
erlotinib, an effective epidermal growth factor receptor tyrosine kinase inhibitor, induces p27kip1 up-regulation and nuclear translocation in association with cell..
apetx1 from sea anemone anthopleura elegantissima is a gating modifier peptide toxin of the human ether-a-go-go- related potassium channel
ur-1505, a new salicylate, blocks t cell activation through nuclear factor of activated t cells
molecular approximations between residues 21 and 23 of secretin and its receptor: development of a model for peptide docking with the amino terminus of the secretin..
a novel multivalent ligand that bridges the allosteric and orthosteric binding sites of the m2 muscarinic receptor
bradykinin-induced nuclear factor of activated t-cells-dependent transcription in rat dorsal root ganglion neurons
novel stable camptothecin derivatives replacing the e-ring lactone by a ketone function are potent inhibitors of topoisomerase i and promising antitumor drugs
characterization of an nbs1 c-terminal peptide that can inhibit ataxia telangiectasia mutated (atm)-mediated dna damage responses and enhance radiosensitivity
molecular interaction of a potent nonpeptide agonist with the chemokine receptor ccr8
critical role for sphingosine kinase-1 in regulating survival of neuroblastoma cells exposed to amyloid-β peptide
transcriptional regulation of brain-derived neurotrophic factor in the amygdala during consolidation of fear memory
β1 (kcnmb1) subunits mediate lithocholate activation of large-conductance ca2+-activated k+ channels and dilation in small, resistance-size arteries
5-androstenediol promotes survival of -irradiated human hematopoietic progenitors through induction of nuclear factor-b activation and granulocyte colony-stimulatin..
identification of the atypical l-type ca2+ channel blocker diltiazem and its metabolites as ghrelin receptor agonists
multidrug resistance proteins 2 and 3 provide alternative routes for hepatic excretion of morphine-glucuronides
caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human co..
glitazones induce astroglioma cell death by releasing reactive oxygen species from mitochondria: modulation of cytotoxicity by nitric oxide
suppression of osteoclastogenesis by n,n-dimethyl-d-erythro-sphingosine: a sphingosine kinase inhibition-independent action
n-ethylmaleimide-sensitive factor regulates β2 adrenoceptor trafficking and signaling in cardiomyocytes
inhibition of hypoxia-induced increase of blood-brain barrier permeability by yc-1 through the antagonism of hif-1 accumulation and vegf expression
desensitization of the dopamine d1 and d2 receptor hetero-oligomer mediated calcium signal by agonist occupancy of either receptor
structure-function studies of allosteric agonism at m2 muscarinic acetylcholine receptors
a selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis