differential selection of acridine resistance mutations in human dna topoisomerase ii is dependent on the acridine structure
the 1b-adrenoceptor exists as a higher-order oligomer: effective oligomerization is required for receptor maturation, surface delivery, and function
rgs4 modulates serotonin signaling in prefrontal cortex and links to serotonin dysfunction in a rat model of schizophrenia
n-terminal residues control proteasomal degradation of rgs2, rgs4, and rgs5 in human embryonic kidney 293 cells
brca1 contributes to cell cycle arrest and chemoresistance in response to the anticancer agent irofulven
high-throughput screening for small-molecule activators of neutrophils: identification of novel n-formyl peptide receptor agonists
voltage-sensitive oxonol dyes are novel large-conductance ca2+-activated k+ channel activators selective for 1 and 4 but not for 2 subunits
function of both sinusoidal and canalicular transporters controls the concentration of organic anions within hepatocytes
loss of the high-affinity pentamidine transporter is responsible for high levels of cross-resistance between arsenical and diamidine drugs in african trypanosomes
methylmercury-induced increase of intracellular ca2+ increases spontaneous synaptic current frequency in rat cerebellar slices
conjugated bile acids regulate hepatocyte glycogen synthase activity in vitro and in vivo via gi signaling
protein kinase c-dependent mitochondrial translocation of proapoptotic protein bax on activation of inducible nitric-oxide synthase in rostral ventrolateral medulla..
structure-based identification of novel human -glutamylcysteine synthetase inhibitors
in vivo regulation of homer1a expression in the striatum by cocaine
activation of camp-dependent signaling pathway induces mouse organic anion transporting polypeptide 2 expression
structure of the d(cgcgaattcgcg)2 complex of the minor groove binding alkylating agent alkamin studied by mass spectrometry
interaction of gq and kir3, g protein-coupled inwardly rectifying potassium channels
constitutive trafficking-more than just running in circles?
the highly conserved dry motif of class a g protein-coupled receptors: beyond the ground state
concurrent administration of neu2000 and lithium produces marked improvement of motor neuron survival, motor function, and mortality in a mouse model of amyotrophic..
an essential role for constitutive endocytosis, but not activity, in the axonal targeting of the cb1 cannabinoid receptor
genetic evidence for a protective role of heat shock factor 1 against irritant-induced gastric lesions
uncovering the pharmacology of the g protein-coupled receptor gpr40: high apparent constitutive activity in guanosine 5'-o-(3-[35s]thio)triphosphate binding studies..