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《分子药理学杂志》2007年第03期

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dna (cytosine-5) methyltransferase inhibitors: a potential therapeutic agent for schizophrenia
native rat hippocampal 5-ht1a receptors show constitutive activity
dna methyltransferase inhibitors coordinately induce expression of the human reelin and glutamic acid decarboxylase 67 genes
inhibition of the c-jun n-terminal kinase-mediated mitochondrial cell death pathway restores auditory function in sound-exposed animals
tumor necrosis factor and endothelin-1 increase p-glycoprotein expression and transport activity at the blood-brain barrier
isolation and structure-activity of µ-conotoxin tiiia, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels
protease-activated receptors differentially regulate human platelet activation through a phosphatidic acid-dependent pathway
the nucleotide analog cidofovir suppresses basic fibroblast growth factor (fgf2) expression and signaling and induces apoptosis in fgf2-overexpressing endothelial c..
amino-pyrrolidine tricarboxylic acids give new insight into group iii metabotropic glutamate receptor activation mechanism
analysis of mammalian carboxylesterase inhibition by trifluoromethylketone-containing compounds
identification of leu276 of the s1p1 receptor and phe263 of the s1p3 receptor in interaction with receptor specific agonists by molecular modeling, site-directed mu..
reactive oxygen species and p38 mitogen-activated protein kinase activate bax to induce mitochondrial cytochrome c release and apoptosis in response to malonate
benzo[a]pyrene-7,8-dihydrodiol promotes checkpoint activation and g2/m arrest in human bronchoalveolar carcinoma h358 cells
modulating the folding of p-glycoprotein and cystic fibrosis transmembrane conductance regulator truncation mutants with pharmacological chaperones
mutational disruption of a conserved disulfide bond in muscarinic acetylcholine receptors attenuates positive homotropic cooperativity between multiple allosteric s..
ca2+ permeability of the (4)3(2)2 stoichiometry greatly exceeds that of (4)2(2)3 human acetylcholine receptors
novel g423s mutation of human 7 nicotinic receptor promotes agonist-induced desensitization by a protein kinase c-dependent mechanism
pioglitazone inhibits androgen production in nci-h295r cells by regulating gene expression of cyp17 and hsd3b2
evidence for direct regulation of myocardial na+/h+ exchanger isoform 1 phosphorylation and activity by 90-kda ribosomal s6 kinase (rsk): effects of the novel and s..
transcriptional regulation of human cyp2a13 expression in the respiratory tract by ccaat/enhancer binding protein and epigenetic modulation
hepatic ischemia-reperfusion induces renal heme oxygenase-1 via nf-e2-related factor 2 in rats and mice
characterization and comparison of nicotine and cotinine metabolism in vitro and in vivo in dba/2 and c57bl/6 mice
dopamine transporter activity mediates amphetamine-induced inhibition of akt through a ca2+/calmodulin-dependent kinase ii-dependent mechanism
the antiestrogen tamoxifen activates bk channels and stimulates proliferation of mcf-7 breast cancer cells
identification of a molecular target mediating the general anesthetic actions of pentobarbital
up-regulation of 150-kda oxygen-regulated protein by celecoxib in human gastric carcinoma cells
4-hydroxy-2-nonenal adduction of extracellular signal-regulated kinase (erk) and the inhibition of hepatocyte erk-est-like protein-1-activating protein-1 signal tra..
the effects of central nervous system-active valproic acid constitutional isomers, cyclopropyl analogs, and amide derivatives on neuronal growth cone behavior
probing hiv-1 integrase inhibitor binding sites with position-specific integrase-dna cross-linking assays
neurokinin-3 receptor-specific antagonists talnetant and osanetant show distinct mode of action in cellular ca2+ mobilization but display similar binding kinetics a..
essential role for class ii phosphoinositide 3-kinase -isoform in ca2+-induced, rho- and rho kinase-dependent regulation of myosin phosphatase and contraction in is..
molecular interactions underlying the unusually high adenosine affinity of a novel trypanosoma brucei nucleoside transporter
activation of the cxcr3 chemokine receptor through anchoring of a small molecule chelator ligand between tm-iii, -iv, and -vi
atp6v0c competes with von hippel-lindau protein in hypoxia-inducible factor 1 (hif-1) binding and mediates hif-1 expression by bafilomycin a1
role of nuclear factor-b and protein kinase c signaling in the expression of the kinin b1 receptor in human vascular smooth muscle cells
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