molecular pharmacology in the postgenomic era
down-regulation of inhibitor of apoptosis proteins by deguelin selectively induces apoptosis in breast cancer cells
subunit-specific roles of glycine-binding domains in activation of nr1/nr3 n-methyl-d-aspartate receptors
µ-opioid receptor activation modulates transient receptor potential vanilloid 1 (trpv1) currents in sensory neurons in a model of inflammatory pain
interaction of the µ-opioid receptor with synaptophysin influences receptor trafficking and signaling
estrogen receptor antagonist fulvestrant (ici 182,780) inhibits the anti-inflammatory effect of glucocorticoids
role of dioxin response element and nuclear factor-b motifs in 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated regulation of fas and fas ligand expression
in silico prediction of pregnane x receptor activators by machine learning approache
identification of small-molecule inhibitors of rgs4 using a high-throughput flow cytometry protein interaction assay
regulation of human cone cyclic nucleotide-gated channels by endogenous phospholipids and exogenously applied phosphatidylinositol 3,4,5-trisphosphate
independent mechanistic inhibition of cdc25 phosphatases by a natural product caulibugulone
in vivo responsiveness to ezetimibe correlates with niemann-pick c1 like-1 (npc1l1) binding affinity: comparison of multiple species npc1l1 orthologs
motexafin gadolinium-induced cell death correlates with heme oxygenase-1 expression and inhibition of p450 reductase-dependent activities
repression of human gsta1 by interleukin-1 is mediated by variant hepatic nuclear factor-1c
embelin, an inhibitor of x chromosome-linked inhibitor-of-apoptosis protein, blocks nuclear factor-b (nf-b) signaling pathway leading to suppression of nf-b-regulat..
the dietary isothiocyanate sulforaphane is an antagonist of the human steroid and xenobiotic nuclear receptor
amphetamine induces a calcium/calmodulin-dependent protein kinase ii-dependent reduction in norepinephrine transporter surface expression linked to changes in synta..
the effect of low ph on breast cancer resistance protein (abcg2)-mediated transport of methotrexate, 7-hydroxymethotrexate, methotrexate diglutamate, folic acid, mi..
cellular retinoic acid bioavailability determines epithelial integrity: role of retinoic acid receptor agonists in colitis
human chorionic gonadotropin modulates prostate cancer cell survival after irradiation or hmg coa reductase inhibitor treatment
molecular basis for the antiproliferative effect of agmatine in tumor cells of colonic, hepatic, and neuronal origin
neurokinin 1 receptors trigger overlapping stimulation and inhibition of cav2.3 (r-type) calcium channels
characterization of the tritium-labeled analog of l-threo--benzyloxyaspartate binding to glutamate transporters
carbohydrate-binding agents efficiently prevent dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (dc-sign)-directed hiv-1 transmission..
pyrrolidine dithiocarbamate inhibits induction of immunoproteasome and decreases survival in a rat model of amyotrophic lateral sclerosis
phosphorylation of g11 protein contributes to agonist-induced desensitization of 5-ht2a receptor signaling
rasgrp1 confers the phorbol ester-sensitive phenotype to el4 lymphoma cells
short polybasic peptide sequences are potent inhibitors of pc5/6 and pc7: use of positional scanning-synthetic peptide combinatorial libraries as a tool for the opt..
zoledronic acid activates the dna s-phase checkpoint and induces osteosarcoma cell death characterized by apoptosis-inducing factor and endonuclease-g translocation..
geldanamycin interferes with the 90-kda heat shock protein, affecting lipopolysaccharide-mediated interleukin-1 expression and apoptosis within macrophages
reversion of structure-activity relationships of antitumor platinum complexes by acetoxime but not hydroxylamine ligands
an extract from the medicinal plant phyllanthus acidus and its isolated compounds induce airway chloride secretion: a potential treatment for cystic fibrosis
translational regulation of rat multidrug resistance-associated protein 2 expression is mediated by upstream open reading frames in the 5' untranslated region
structural determinants for high-affinity zolpidem binding to gaba-a receptors
comments on "calpain mediates the dioxin-induced activation and down-regulation of the aryl hydrocarbon receptor"
response to comments on "calpain mediates the dioxin-induced activation and down-regulation of the aryl hydrocarbon receptor"
characterization of 2-adrenergic receptor dephosphorylation: comparison with the rate of resensitization
c-abl kinase regulates curcumin-induced cell death through activation of c-jun n-terminal kinase
the positional influence of the helical geometry of the heteroduplex substrate on human rnase h1 catalysis
human rnase h1 discriminates between subtle variations in the structure of the heteroduplex substrate
amino acid residues in the p2x7 receptor that mediate differential sensitivity to atp and bzatp