baffled by bafilomycin: an anticancer agent that induces hypoxia-inducible factor-1 expression
nicotinic acid-induced flushing is mediated by activation of epidermal langerhans cells
[d-trp8]--melanocyte-stimulating hormone exhibits anti-inflammatory efficacy in mice bearing a nonfunctional mc1r (recessive yellow e/e mouse)
bafilomycin induces the p21-mediated growth inhibition of cancer cells under hypoxic conditions by expressing hypoxia-inducible factor-1
comparison of the activities of the truncated halichondrin b analog nsc 707389 (e7389) with those of the parent compound and a proposed binding site on tubulin
pharmacological inhibition of histone deacetylases by suberoylanilide hydroxamic acid specifically alters gene expression and reduces ischemic injury in the mouse b..
rapid and robust protection against cocaine-induced lethality in rats by the bacterial cocaine esterase
conformational constraining of inactive and active states of a seven transmembrane receptor by metal ion site engineering in the extracellular end of transmembrane ..
2,3,7,8-tetrachlorodibenzo-p-dioxin and epidermal growth factor cooperatively suppress peroxisome proliferator-activated receptor-1 stimulation and restore focal ad..
ginsenoside re, a main phytosterol of panax ginseng, activates cardiac potassium channels via a nongenomic pathway of sex hormones
stimulation of amp-activated protein kinase is essential for the induction of drug metabolizing enzymes by phenobarbital in human and mouse liver
insights into the cholecystokinin 2 receptor binding site and processes of activation
eriocalyxin b inhibits nuclear factor-b activation by interfering with the binding of both p65 and p50 to the response element in a noncompetitive manner
molecular interaction of serotonin 5-ht2a receptor residues phe339(6.51) and phe340(6.52) with superpotent n-benzyl phenethylamine agonists
dissecting the roles of checkpoint kinase 1/cdc2 and mitogen-activated protein kinase kinase 1/2/extracellular signal-regulated kinase 1/2 in relation to 7-hydroxys..
structural requirements of transmembrane domain 3 for activation by the m1 muscarinic receptor agonists ac-42, ac-260584, clozapine, and n-desmethylclozapine: evide..
determinants of 1-piperidinecarboxamide, n-[2-[[5-amino-l-[[4-(4-pyridinyl)-l-piperazinyl]carbonyl]pentyl]amino]-1-[(3,5-dibromo-4-hydroxyphenyl)methyl]-2-oxoethyl]..
camp inhibits transforming growth factor--stimulated collagen synthesis via inhibition of extracellular signal-regulated kinase 1/2 and smad signaling in cardiac fi..
essential role of c-rel in nitric-oxide synthase-2 transcriptional activation: time-dependent control by salicylate
2,3-butanedione monoxime affects cystic fibrosis transmembrane conductance regulator channel function through phosphorylation-dependent and phosphorylation-independ..
point mutations in the transmembrane region of gabab2 facilitate activation by the positive modulator n,n'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-dia..
role of the agonist binding site in up-regulation of neuronal nicotinic 42 receptors
molecular changes evoked by triethylenetetramine treatment in the extracellular matrix of the heart and aorta in diabetic rats
the mechanism of activity-dependent sodium channel inhibition by the antidepressants fluoxetine and desipramine
methamphetamine-induced sensitization differentially alters pcreb and fosb throughout the limbic circuit of the mammalian brain
ym-244769, a novel na+/ca2+ exchange inhibitor that preferentially inhibits ncx3, efficiently protects against hypoxia/reoxygenation-induced sh-sy5y neuronal cell d..
analysis of the dissociated steroid ru24858 does not exclude a role for inducible genes in the anti-inflammatory actions of glucocorticoids
endogenous hepatic expression of the hepatitis b virus x-associated protein 2 is adequate for maximal association with aryl hydrocarbon receptor-90-kda heat shock p..
the h+-linked monocarboxylate transporter (mct1/slc16a1): a potential therapeutic target for high-risk neuroblastoma
neurotoxicity of domoic acid in cerebellar granule neurons in a genetic model of glutathione deficiency
the important role of bcrp (abcg2) in the biliary excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in mice