hypoxia-inducible factor-1 (hif-1)
calpain mediates the dioxin-induced activation and down-regulation of the aryl hydrocarbon receptor
circumventing recombination events encountered with production of a clinical-grade adenoviral vector with a double-expression cassette
enhancement of hippocampal pyramidal cell excitability by the novel selective slow-afterhyperpolarization channel blocker 3-(triphenylmethylaminomethyl)pyridine (uc..
a three-dimensional quantitative structure-activity relationship study of the inhibition of the atpase activity and the strand passing catalytic activity of topoiso..
an inner pore residue (asn406) in the nav1.5 channel controls slow inactivation and enhances mibefradil block to t-type ca2+ channel levels
inhibition of in vivo glioma growth and invasion by peroxisome proliferator-activated receptor agonist treatment
overcoming trastuzumab resistance in her2-overexpressing breast cancer cells by using a novel celecoxib-derived phosphoinositide-dependent kinase-1 inhibitor
the concerted contribution of the s4-s5 linker and the s6 segment to the modulation of a kv channel by 1-alkanols
synergistic effects of peloruside a and laulimalide with taxoid site drugs, but not with each other, on tubulin assembly
transmembrane domain vii of the human apical sodium-dependent bile acid transporter asbt (slc10a2) lines the substrate translocation pathway
distinct signaling profiles of 1 and 2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of e..
roles for the trypanosoma brucei p2 transporter in db75 uptake and resistance
salvicine functions as novel topoisomerase ii poison by binding to atp pocket
functional genetic diversity in the high-affinity carnitine transporter octn2 (slc22a5)
cannabinoid receptor-mediated apoptosis induced by r(+)-methanandamide and win55,212-2 is associated with ceramide accumulation and p38 activation in mantle cell ly..
curcumin inhibits hypoxia-inducible factor-1 by degrading aryl hydrocarbon receptor nuclear translocator: a mechanism of tumor growth inhibition
a single decoy oligodeoxynucleotides targeting multiple oncoproteins produces strong anticancer effects
a comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/na+ symporters (nss) aids in the use of the leut structure to probe nss str..
intersectin regulates epidermal growth factor receptor endocytosis, ubiquitylation, and signaling
plitidepsin cellular binding and rac1/jnk pathway activation depend on membrane cholesterol content
electron spin resonance and chemiluminescence analyses to elucidate the vasodilating mechanism of sodium nitroprusside
transcriptional activation of cyp2c9, cyp1a1, and cyp1a2 by hepatocyte nuclear factor 4 requires coactivators peroxisomal proliferator activated receptor- coactivat..
heterogeneity of nicotinic cholinergic receptors in rat superior cervical and nodose ganglia
adenylyl cyclase 6 overexpression decreases the permeability of endothelial monolayers via preferential enhancement of prostacyclin receptor function
molecular aspects of antitumor effects of a new platinum(iv) drug
involvement of tissue plasminogen activator-plasmin system in depolarization-evoked dopamine release in the nucleus accumbens of mice
corticostriatal up-regulation of activity-regulated cytoskeletal-associated protein expression after repeated exposure to cocaine
modification of oatp2b1-mediated transport by steroid hormones
calmodulin-stimulated adenylyl cyclase gene deletion affects morphine responses
a critical role for the short intracellular c terminus in receptor activity-modifying protein function
voltage-dependent block of n-methyl-d-aspartate receptors by dopamine d1 receptor ligands
inhibitory gating modulation of small conductance ca2+-activated k+ channels by the synthetic compound (r)-n-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphtylamine (..
probing the existence of g protein-coupled receptor dimers by positive and negative ligand-dependent cooperative binding
nerve growth factor regulates adrenergic expression
monitoring the activation state of insulin/insulin-like growth factor-1 hybrid receptors using bioluminescence resonance energy transfer
induction of apoptosis in estrogen receptor-negative breast cancer cells by natural and synthetic cyclopentenones: role of the ib kinase/nuclear factor-b pathway
a 46-amino acid segment in phosphodiesterase-5 gaf-b domain provides for high vardenafil potency over sildenafil and tadalafil and is involved in phosphodiesterase-..
a new mechanism of methotrexate action revealed by target screening with affinity beads