transient receptor potential channels and caveolin-1: good friends in tight spaces
is it go or no go for s-nitrosylation modification-based therapies of cystic fibrosis transmembrane regulator trafficking?
role of ectodomain lysines in the subunits of the heteromeric p2x2/3 receptor
the farnesoid x receptor promotes adipocyte differentiation and regulates adipose cell function in vivo
caveolin-1 regulates store-operated ca2+ influx by binding of its scaffolding domain to transient receptor potential channel-1 in endothelial cells
antioxidant down-regulates interleukin-18 expression in asthma
the bioreduction of a series of benzoquinone ansamycins by nad(p)h:quinone oxidoreductase 1 to more potent heat shock protein 90 inhibitors, the hydroquinone ansamy..
binding site of a novel kv1.5 blocker: a "foot in the door" against atrial fibrillation
in vivo activation of human pregnane x receptor tightens the blood-brain barrier to methadone through p-glycoprotein up-regulation
effects of potent inhibitors of the retinoid cycle on visual function and photoreceptor protection from light damage in mice
solution nmr of acetylcholine binding protein reveals agonist-mediated conformational change of the c-loop
cb1 receptor antagonism increases hippocampal acetylcholine release: site and mechanism of action
diabetes-induced mechanical hyperalgesia involves spinal mitogen-activated protein kinase activation in neurons and microglia via n-methyl-d-aspartate-dependent mec..
role in the selectivity of neonicotinoids of insect-specific basic residues in loop d of the nicotinic acetylcholine receptor agonist binding site
risperidone irreversibly binds to and inactivates the h5-ht7 serotonin receptor
on the mechanism of action of 9-o-arylalkyloxime derivatives of 6-o-mycaminosyltylonolide, a new class of 16-membered macrolide antibiotics
regulation of mouse hepatic -amino-β-carboxymuconate--semialdehyde decarboxylase, a key enzyme in the tryptophan-nicotinamide adenine dinucleotide pathway, by hepa..
endocrine regulation of gender-divergent mouse organic anion-transporting polypeptide (oatp) expression
the cannabinoid cb1 receptor antagonist rimonabant (sr141716) inhibits human breast cancer cell proliferation through a lipid raft-mediated mechanism
molecular determinants of pyrantel selectivity in nicotinic receptors
biophysical characterization of the new human ether-a-go-go-related gene channel opener ns3623 [n-(4-bromo-2-(1h-tetrazol-5-yl)-phenyl)-n'-(3'-trifluoromethylphenyl..
focal adhesion kinase and protein kinase b cooperate to suppress doxorubicin-induced apoptosis of breast tumor cells
liver x receptor (lxr)-β regulation in lxr-deficient mice: implications for therapeutic targeting
incorporation of the β3 subunit has a dominant-negative effect on the function of recombinant central-type neuronal nicotinic receptors
β3 subunits promote expression and nicotine-induced up-regulation of human nicotinic 6* nicotinic acetylcholine receptors expressed in transfected cell lines
role of endogenous xap2 protein on the localization and nucleocytoplasmic shuttling of the endogenous mouse ahb-1 receptor in the presence and absence of ligand
prevention of platelet glycoprotein iib/iiia activation by 3,4-methylenedioxy-β-nitrostyrene, a novel tyrosine kinase inhibitor
contribution of the major copper influx transporter ctr1 to the cellular accumulation of cisplatin, carboplatin, and oxaliplatin
jx401, a p38 inhibitor containing a 4-benzylpiperidine motif, identified via a novel screening system in yeast
point mutations in either subunit of the gabab receptor confer constitutive activity to the heterodimer
17β-estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the g protein-coupled receptor gpr30
inhibition of ca2+ influx is required for mitochondrial reactive oxygen species-induced endoplasmic reticulum ca2+ depletion and cell death in leukemia cells
s-nitrosylating agents: a novel class of compounds that increase cystic fibrosis transmembrane conductance regulator expression and maturation in epithelial cells
ras-dependent recruitment of c-myc for transcriptional activation of nucleophosmin/b23 in highly malignant u1 bladder cancer cells
sazetidine-a, a novel ligand that desensitizes 4β2 nicotinic acetylcholine receptors without activating them
the regulator of g protein signaling domain of axin selectively interacts with g12 but not g13