potential therapeutic gene for the treatment of ischemic disease: ad2/hypoxia-inducible factor-1 (hif-1)/vp16 enhances b-type natriuretic peptide gene expression vi..
enantiomers of neuroactive steroids support a specific interaction with the gaba-c receptor as the mechanism of steroid action
decursin inhibits induction of inflammatory mediators by blocking nuclear factor-b activation in macrophages
ib kinase-2-independent and -dependent inflammation in airway disease models: relevance of ikk-2 inhibition to the clinic
development of a novel nitro-derivative of noscapine for the potential treatment of drug-resistant ovarian cancer and t-cell lymphoma
short- and long-term regulation of adenylyl cyclase activity by -opioid receptor are mediated by gi2 in neuroblastoma n2a cells
suppression and regression of choroidal neovascularization by systemic administration of an 51 integrin antagonist
phosphatase and tensin homolog deleted on chromosome 10 (pten) reduces vascular endothelial growth factor expression in allergen-induced airway inflammation
a novel vitamin d derivative activates bone morphogenetic protein signaling in mcf10 breast epithelial cells
determination of binding site residues responsible for the subunit selectivity of novel marine-derived compounds on kainate receptors
antieosinophilic activity of orazipone
novel compound 2-methyl-2h-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazo-phenyl)-amide (ch-223191) prevents 2,3,7,8-tcdd-induced toxicity by antagonizing the ar..
induction of apoptosis in renal cell carcinoma by reactive oxygen species: involvement of extracellular signal-regulated kinase 1/2, p38/, cyclooxygenase-2 down-reg..
mutations distal to the substrate site can affect varicella zoster virus thymidine kinase activity: implications for drug design
endoplasmic reticulum-associated degradation of cytochrome p450 cyp3a4 in saccharomyces cerevisiae: further characterization of cellular participants and structural..
the two-state dimer receptor model: a general model for receptor dimers
transactivation of rat apical sodium-dependent bile acid transporter and increased bile acid transport by 1,25-dihydroxyvitamin d3 via the vitamin d receptor
a common regulatory region functions bidirectionally in transcriptional activation of the human cyp1a1 and cyp1a2 genes
phoneutria nigriventer toxin 1: a novel, state-dependent inhibitor of neuronal sodium channels that interacts with µ conotoxin binding sites
suppression of the phosphorylation of receptor tyrosine phosphatase- on the src-independent site tyrosine 789 by reactive oxygen species
2-fluoro-3-(4-nitro-phenyl)deschloroepibatidine is a novel potent competitive antagonist of human neuronal 42 nachrs
a constitutively active hypoxia-inducible factor-1/vp16 hybrid factor activates expression of the human b-type natriuretic peptide gene
t-type calcium channels are inhibited by fluoxetine and its metabolite norfluoxetine
desensitization of no/cgmp signaling in smooth muscle: blood vessels versus airways
potentiation of native and recombinant p2x7-mediated calcium signaling by arachidonic acid in cultured cortical astrocytes and human embryonic kidney 293 cells
distinct receptor activity-modifying protein domains differentially modulate interaction with calcitonin receptors
the interaction of an impermeant cation with the sheep cardiac ryr channel alters ryanoid association
neurochemical characterization of a neuroprotective compound from parawixia bistriata spider venom that inhibits synaptosomal uptake of gaba and glycine
recombinant enzymes overexpressed in bacteria show broad catalytic specificity of human cytochrome p450 2w1 and limited activity of human cytochrome p450 2s1
dual potentiating and inhibitory actions of a benz[e]indene neurosteroid analog on recombinant 122 gabaa receptors
in vitro and in vivo nuclear factor-b inhibitory effects of the cell-penetrating penetratin peptide
modulation by ll-37 of the responses of salivary glands to purinergic agonists
ultrasound stimulates cyclooxygenase-2 expression and increases bone formation through integrin, focal adhesion kinase, phosphatidylinositol 3-kinase, and akt pathw..
the suramin analog 4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis (carbonylimino)))tetra-kis-benzenesulfonic acid (nf110) potently blocks p2x3 receptors: su..
g12/13- and rho-dependent activation of phospholipase c- by lysophosphatidic acid and thrombin receptors
the aryl hydrocarbon receptor agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin alters the circadian rhythms, quiescence, and expression of clock genes in murine hematopo..
sulfotransferase (sult) 1a1 polymorphic variants *1, *2, and *3 are associated with altered enzymatic activity, cellular phenotype, and protein degradation