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《分子药理学杂志》2005年第04期

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pharmacological differences between human and guinea pig histamine h1 receptors: asn84 (2.61) as key residue within an additional binding pocket in the h1 receptor
fusion polypeptides that inhibit exocytosis: fusing aptamer and cell-penetrating peptide technologies and pharmacologies
meclofenamic acid and diclofenac, novel templates of kcnq2/q3 potassium channel openers, depress cortical neuron activity and exhibit anticonvulsant properties
molecular determinants of substrate/inhibitor binding to the human and rabbit renal organic cation transporters hoct2 and rboct2
molecular determinants of the agonist binding domain of a p2x receptor channel
phosphatidylinositol-4,5-bisphosphate: actin dynamics and the regulation of atp-dependent and -independent secretion
extracellular loop 3 (el3) and el3-proximal transmembrane helix 7 of the mammalian type i and type ii gonadotropin-releasing hormone (gnrh) receptors determine diff..
glycosaminoglycans and protein disulfide isomerase-mediated reduction of hiv env
trpv1b, a functional human vanilloid receptor splice variant
molecular interactions between matrilysin and the matrix metalloproteinase inhibitor doxycycline investigated by deuterium exchange mass spectrometry
a novel class of fusion polypeptides inhibits exocytosis
src family kinase inhibitors block amphiregulin-mediated autocrine erbb signaling in normal human keratinocytes
the natural mutation encoding a c terminus-truncated 5-hydroxytryptamine2b receptor is a gain of proliferative functions
n-methyl-d-aspartate and brain-derived neurotrophic factor induce distinct profiles of extracellular signal-regulated kinase, mitogen- and stress-activated kinase, ..
cotreatment with suberanoylanilide hydroxamic acid and 17-allylamino 17-demethoxygeldanamycin synergistically induces apoptosis in bcr-abl+ cells sensitive and resi..
sphingosine 1-phosphate receptors mediate the lipid-induced camp accumulation through cyclooxygenase-2/prostaglandin i2 pathway in human coronary artery smooth musc..
selective inhibition of topoisomerase i and various steps of spliceosome assembly by diospyrin derivatives
involvement of gi/o proteins in nerve growth factor-stimulated phosphorylation and degradation of tuberin in pc-12 cells and cortical neurons
interaction of the insulin receptor with the receptor-like protein tyrosine phosphatases ptp and ptp in living cells
differential sensitivity of kir2 inward-rectifier potassium channels to a mitochondrial uncoupler: identification of a regulatory site
developmental changes of gaba synaptic transient in cerebellar granule cells
-arrestin 2-dependent angiotensin ii type 1a receptor-mediated pathway of chemotaxis
glycogen synthase kinase 3 activity mediates neuronal pentraxin 1 expression and cell death induced by potassium deprivation in cerebellar granule cells
-arrestin-dependent spontaneous 1a-adrenoceptor endocytosis causes intracellular transportation of -blockers via recycling compartments
arsenite inhibition of cyp1a1 induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin is independent of cell cycle arrest
regulation of human hepatic hydroxysteroid sulfotransferase gene expression by the peroxisome proliferator-activated receptor transcription factor
the ccr5 receptor-based mechanism of action of 873140, a potent allosteric noncompetitive hiv entry inhibitor
trace amines depress gabab response in dopaminergic neurons by inhibiting g--gated inwardly rectifying potassium channels
residue 33 of human equilibrative nucleoside transporter 2 is a functionally important component of both the dipyridamole and nucleoside binding sites
the xenobiotic-metabolizing enzymes arylamine n-acetyltransferases in human lens epithelial cells: inactivation by cellular oxidants and uvb-induced oxidative stress
cross-resistance to death ligand-induced apoptosis in cisplatin-selected hela cells associated with overexpression of ddb2 and subsequent induction of cflip
benzodiazepines affect channel opening of gabaa receptors induced by either agonist binding site
the new anticonvulsant retigabine favors voltage-dependent opening of the kv7.2 (kcnq2) channel by binding to its activation gate
nuclear factor-b decoy oligodeoxynucleotides prevent acute lung injury in mice with cecal ligation and puncture-induced sepsis
the size of a single residue of the sulfonylurea receptor dictates the effectiveness of katp channel openers
anuroctoxin, a new scorpion toxin of the -ktx 6 subfamily, is highly selective for kv1.3 over ikca1 ion channels of human t lymphocytes
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