structural determinants of arylacetic acid nonsteroidal anti-inflammatory drugs necessary for binding and activation of the prostaglandin d2 receptor crth2
an orphan receptor adopted by a family of transmitters
transfected 3- but not 2-adrenergic receptors regulate cystic fibrosis transmembrane conductance regulator activity via a new pathway involving the mitogen-activate..
role of the c terminus in neuropeptide y y receptor desensitization and internalization
modulation of udp-glucuronosyltransferase function by cytochrome p450: evidence for the alteration of ugt2b7-catalyzed glucuronidation of morphine by cyp3a4
urinary trypsin inhibitor protects against systemic inflammation induced by lipopolysaccharide
constitutive expression of peroxisome proliferator-activated receptor -regulated genes in dwarf mice
functional characterization of go signaling through g protein-regulated inducer of neurite outgrowth 1
tyr702 is an important determinant of agonist binding and domain closure of the ligand-binding core of glur2
the aryl hydrocarbon receptor is required for developmental closure of the ductus venosus in the neonatal mouse
differential regulation and relocalization of the platelet p2y receptors after activation: a way to avoid loss of hemostatic properties
pdzk1 directly regulates the function of organic cation/carnitine transporter octn2
activators of cation channels: potential in treatment of channelopathies
the nongenotropic synthetic ligand 4-estren-317-diol is a high-affinity genotropic androgen receptor agonist
a novel strategy for the enhancement of drug absorption using a claudin modulator
macrophage inflammatory protein 2 inhibits -amyloid peptide (1-42)-mediated hippocampal neuronal apoptosis through activation of mitogen-activated protein kinase an..
organotin compounds promote adipocyte differentiation as agonists of the peroxisome proliferator-activated receptor /retinoid x receptor pathway
cultured hippocampal pyramidal neurons express two kinds of gabaa receptors
regulation of serum response factor-dependent gene expression by proteasome inhibitors
activation of the melastatin-related cation channel trpm3 by d-erythro-sphingosine
phosphorylation of cytidine, deoxycytidine, and their analog monophosphates by human ump/cmp kinase is differentially regulated by atp and magnesium
identification of endogenous glucocorticoid repressed genes differentially regulated by a glucocorticoid receptor mutant able to separate between nuclear factor-b a..
residues met89 and ser160 in the human equilibrative nucleoside transporter 1 affect its affinity for adenosine, guanosine, s6-(4-nitrobenzyl)-mercaptopurine ribosi..
deorphanization of gprc6a: a promiscuous l--amino acid receptor with preference for basic amino acids
transcriptional regulation of human ugt1a1 gene expression: activated glucocorticoid receptor enhances constitutive androstane receptor/pregnane x receptor-mediated..
dna damage effects of a polyamide-cbi conjugate in sv40 virions
optimized targeting of polyethylene glycol-stabilized anti-intercellular adhesion molecule 1 oligonucleotide/lipid particles to liver sinusoidal endothelial cells
neuropeptide ff (npff) analogs functionally antagonize opioid activities in npff2 receptor-transfected sh-sy5y neuroblastoma cells
evidence for the functional expression and pharmacological characterization of adenine receptors in native cells and tissues
the hypolipidemic natural product guggulsterone is a promiscuous steroid receptor ligand
biochemical and proteomics approaches to characterize topoisomerase ii cysteines and dna as targets responsible for cisplatin-induced inhibition of topoisomerase ii
digitalis-induced signaling by na+/k+-atpase in human breast cancer cells
role of breast cancer resistance protein (bcrp1/abcg2) in the extrusion of glucuronide and sulfate conjugates from enterocytes to intestinal lumen
dexamethasone up-regulates the inhibitory adaptor protein dok-1 and suppresses downstream activation of the mitogen-activated protein kinase pathway in antigen-stim..
two 1-adrenergic receptor subtypes regulating the vasopressor response have differential roles in blood pressure regulation
differential sensitivities of the human atp-binding cassette transporters abcg2 and p-glycoprotein to cyclosporin a
inadequacy of the janus kinase 2/signal transducer and activator of transcription signal transduction pathway to mediate episodic growth hormone-dependent regulatio..
discovery of a small molecule activator of the human ether-a-go-go-related gene (herg) cardiac k+ channel
rsk4 and pak5 are novel candidate genes in diabetic rat kidney and brain
the aryl hydrocarbon receptor predisposes hepatocytes to fas-mediated apoptosis
in vivo mechanisms of tissue-selective drug toxicity: effects of liver-specific knockout of the nadph-cytochrome p450 reductase gene on acetaminophen toxicity in ki..
rgs2 is a mediator of nitric oxide action on blood pressure and vasoconstrictor signaling