ABSTRACT: Objective To find an ideal biomaterial for internal fixation. Methods Forty rabbits with fracture of the femur diaphysis (superiorcondyle) were treated by intramedullary nailing of femur with composites rod of resorbable DL-polylactic acid (PDLLA)-calcium metaphosphate (CMP), while steinmann's pin as control. The fracture healing, the material degradation and its mechanical properties were studied by X-ray films, macroscopic, microscopic and electron microscopic observations. Results
No significant inflammatory reaction was found, and all the osteotomies were healed, while material was resorbed. Conclusion
The PDLLA-CMP has excellent biocompatibility and mechanical properties, and it can be a promising implant material in orthopaedics surgery.
KEY WORDS: DL-polylactic acid(PLA); calcium metaphosphate(CMP); PDLLA/CMP fiber composites; resorb- able medical material; fracture healing; biocompatibility
CLC number: R873
Document code: A
Article ID: 1671-8267 (2004)01-0058-04
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原版页码：58,59,60,61原版全文
